Zachary Pursell - Dissemin

All papers authored by Zachary Pursell

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2020 Melissa A. Galati, Karl P. Hodel, Miki S. Gams, Sumedha Sudhaman, Taylor Bridge, Walter J. Zahurancik, Nathan A. Ungerleider, Vivian S. Park, Ayse B. Ercan

, Lazar Joksimovic, Iram Siddiqui, Robert Siddaway, Melissa Edwards, Richard de Borja

, Dana Elshaer and 21 other authors

Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade

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Karl P. Hodel, Meijuan J. S. Sun, Nathan Ungerleider, Vivian S. Park, Leonard G. Williams, David L. Bauer, Victoria E. Immethun, Jieqiong Wang, Zucai Suo, Hua Lu, James B. McLachlan, Zachary F. Pursell

POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status

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2019 Pravin Pathak, Wei Yao, Katherine Delaney Hook, Ryan Vik, Fernaldo Richtia Winnerdy, Jonathon Quincy Brown, Bruce C. Gibb

, Zachary F. Pursell

, Anh Tuân Phan

, Janarthanan Jayawickramarajah

Bright G-Quadruplex Nanostructures Functionalized with Porphyrin Lanterns

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Vivian S. Park, Zachary F. Pursell

POLE proofreading defects: Contributions to mutagenesis and cancer

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This paper is made freely available by the publisher.

2017 Harrison M. Penrose, Sandra Heller, Chloe Cable, Hani Nakhoul, Nate Ungerleider, Melody Baddoo, Zachary F. Pursell

, Erik K. Flemington, Susan E. Crawford, Suzana D. Savkovic

In colonic ρ0 (rho0) cells reduced mitochondrial function mediates transcriptomic alterations associated with cancer

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2015 Sarah Eddy, Leena Maddukuri, Amit Ketkar, Maroof K. Zafar, Erin E. Henninger, Zachary F. Pursell

, Robert L. Eoff

Evidence for the Kinetic Partitioning of Polymerase Activity on G-Quadruplex DNA

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Peter van Loo, Richard de Borja, A. Yasemin Göksenin, Adam Shlien, Brittany B. Campbell, R. De Borja, Ludmil B. Alexandrov

, Daniele Merico, David Wedge, P. Van Loo, Patrick S. Tarpey, Paul Coupland, Sam Behjati, Aaron Pollett, Tatiana Lipman and 53 other authors

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

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2014 Eve Shinbrot, A. Yasemin Göksenin, Erin E. Henninger, Nils Weinhold, Kyle R. Covington, A. Yasemin Göksenin, Nikolaus Schultz, Hsu Chao, HarshaVardhan Doddapaneni, Donna M. Muzny, Richard A. Gibbs, Chris Sander, Zachary F. Pursell

, David A. Wheeler

Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication

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Erin E. Henninger, Zachary F. Pursell

DNA polymerase ε and its roles in genome stability

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2013 Anderson Ayuk Agbor, A. Yasemin Göksenin, A. Yasemin Göksenin, Kimberly G. LeCompte, Samuel H. Hans, Zachary F. Pursell

Human Pol ε-Dependent Replication Errors and the Influence of Mismatch Repair on Their Correction

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2012 A. Yasemin Göksenin, A. Yasemin Goksenin, Walter Zahurancik, Kimberly G. LeCompte, David J. Taggart, Zucai Suo, Zachary F. Pursell

Human DNA Polymerase ϵ Is Able to Efficiently Extend from Multiple Consecutive Ribonucleotides*

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Scott A. Lujan

, Jessica S. Williams, Zachary F. Pursell

, Amy A. Abdulovic-Cui, Alan B. Clark, Stephanie A. Nick McElhinny, Thomas A. Kunkel

Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity

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2010 Anna Aksenova, Kirill Volkov, Jaroslaw Maceluch, Zachary F. Pursell

, Igor B. Rogozin, Thomas A. Kunkel, Youri I. Pavlov, Erik Johansson

Mismatch Repair–Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of DNA Polymerase ε

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D. A. Korona, K. G. LeCompte, Z. F. Pursell

The high fidelity and unique error signature of human DNA polymerase

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2008 Z. F. Pursell

, J. T. McDonald

, C. K. Mathews, T. A. Kunkel

Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase replication fidelity

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Zachary F. Pursell

, Thomas A. Kunkel

DNA Polymerase ε: A Polymerase Of Unusual Size (and Complexity)

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2007 Zachary F. Pursell

, Isabelle Isoz, Else-Britt Lundström, Erik Johansson, Thomas A. Kunkel

Yeast DNA Polymerase ε Participates in Leading-Strand DNA Replication

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Z. F. Pursell

, I. Isoz, E.-B. Lundstrom, E. Johansson, T. A. Kunkel

Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase

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2005 Shiwei Song, Zachary F. Pursell

, William C. Copeland, Matthew J. Longley, Thomas A. Kunkel, Christopher K. Mathews

DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity

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2000 Ying Li, Zachary F. Pursell

, Stuart Linn

Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase ε.

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All papers authored by Zachary Pursell