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All papers authored by Romina Alfonsi

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2021 Michele Signore

ORCID

, Romina Alfonsi

ORCID

, Giulia Federici, Simona Nanni, Antonio Addario, Lucia Bertuccini, Aurora Aiello

ORCID

, Anna Laura Di Pace, Isabella Sperduti, Giovanni Muto, Alessandro Giacobbe, Devis Collura, Lidia Brunetto, Giuseppe Simone, Manuela Costantini and 10 other authors

Diagnostic and prognostic potential of the proteomic profiling of serum-derived extracellular vesicles in prostate cancer

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2019 Ludovica Grassi, Romina Alfonsi

ORCID

, Federica Francescangeli

ORCID

, Michele Signore

ORCID

, Maria Laura De Angelis, Antonio Addario, Manuela Costantini, Elisabetta Flex, Andrea Ciolfi, Simone Pizzi, Alessandro Bruselles, Matteo Pallocca, Giuseppe Simone, Mustapha Haoui, Mario Falchi and 9 other authors

Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases

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2018 S. Di Martino, Simona di Martino, Gabriele De Luca, Ludovica Grassi, Giulia Federici, Romina Alfonsi

ORCID

, Michele Signore

ORCID

, Antonio Addario, Laura De Salvo, Federica Francescangeli

ORCID

, Massimo Sanchez, Valentina Tirelli, Giovanni Muto, Isabella Sperduti, Steno Sentinelli and 8 other authors

Renal cancer: new models and approach for personalizing therapy

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Isabella Romeo, Simone Berardozzi

ORCID

, Flavia Bernardi, Paola Infante, Cinzia Ingallina

ORCID

, Sara Toscano, Elisa De Paolis, Miriam Caimano, Romina Alfonsi

ORCID

, Bruno Botta, Mattia Mori

ORCID

, Lucia Di Marcotullio, Francesca Ghirga

Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold

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Romina Alfonsi

ORCID

, Ludovica Grassi, Michele Signore

ORCID

, Désirée Bonci

The Double Face of Exosome-Carried MicroRNAs in Cancer Immunomodulation

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Paola Infante, Roberta Faedda, Flavia Bernardi, Francesca Bufalieri, Ludovica Lospinoso Severini, Romina Alfonsi

ORCID

, Daniela Mazzà, Mariangela Siler, Sonia Coni, Agnese Po, Marialaura Petroni, Elisabetta Ferretti, Mattia Mori

ORCID

, Enrico De Smaele, Gianluca Canettieri and 8 other authors

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis

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Andrea Calcaterra, Valentina Iovine, Bruno Botta, Deborah Quaglio, Ilaria D’Acquarica, Alessia Ciogli, Antonia Iazzetti, Ludovica Lospinoso Severini, Paola Infante, Romina Alfonsi

ORCID

, Lucia Di Marcotullio, Mattia Mori, Francesca Ghirga

Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

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2017 Roberta De Mori, Marta Romani, Stefano D’Arrigo, Maha S. Zaki, Elisa Lorefice, Silvia Tardivo, Tommaso Biagini, Valentina Stanley, Damir Musaev, Joel Fluss, Alessia Micalizzi, Sara Nuovo, Barbara Illi, Luisa Chiapparini, Lucia Di Marcotullio and 15 other authors

Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects

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Romina Alfonsi

ORCID

ORCID

, Sandro Cacchi, Lucia Di Marcotullio, Giancarlo Fabrizi, Roberta Faedda, Antonella Goggiamani

ORCID

, Antonia Iazzetti, Mattia Mori

Design, palladium-catalyzed synthesis, and biological investigation of 2-substituted 3-aroylquinolin-4(1H)-ones as inhibitors of the Hedgehog signaling pathway.

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2016 Paola Infante, Romina Alfonsi

ORCID

, Cinzia Ingallina

ORCID

, Deborah Quaglio, Francesca Ghirga, Ilaria D'Acquarica, Flavia Bernardi, Laura Di Magno, Gianluca Canettieri, Isabella Screpanti, Alberto Gulino, Bruno Botta, Mattia Mori, Lucia Di Marcotullio

Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype

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Gessica Filocamo, Mirko Brunetti, Fabrizio Colaceci, Romina Sasso, Mirella Tanori, Emanuela Pasquali, Romina Alfonsi

ORCID

, Mariateresa Mancuso, Anna Saran, Armin Lahm, Lucia Di Marcotullio, Christian Steinkuhler, Simonetta Pazzaglia

MK-4101 - a potent inhibitor of the hedgehog pathway - is highly active against medulloblastoma and basal cell carcinoma

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2015 Giuseppe La Regina, Ruoli Bai, Antonio Coluccia, Valeria Famiglini, Sveva Pelliccia, Sara Passacantilli

ORCID

, Carmela Mazzoccoli, Vitalba Ruggieri, Annalisa Verrico, Andrea Miele, Ludovica Monti, Marianna Nalli, Romina Alfonsi

ORCID

, Lucia Di Marcotullio, Alberto Gulino and 18 other authors

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

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Paola Infante, Romina Alfonsi

ORCID

ORCID

, Mattia Mori, Lucia Di Marcotullio

Targeting GLI factors to inhibit the Hedgehog pathway

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Romina Alfonsi

ORCID

Click reaction as a useful tool to creatively combine pharmacophores: The case of Vismodegib

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Paola Infante, Romina Alfonsi

ORCID

, Lucia Di Marcotullio

Insights into Gli Factors Ubiquitylation Methods

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2014 Giuseppe La Regina, Ruoli Bai, Antonio Coluccia, Valeria Famiglini, Sveva Pelliccia, Sara Passacantilli

ORCID

, Carmela Mazzoccoli, Vitalba Ruggieri, Lorenza Sisinni, Alessio Bolognesi, Whilelmina Maria Rensen, Andrea Miele, Marianna Nalli, Romina Alfonsi

ORCID

, Lucia Di Marcotullio and 10 other authors

New Pyrrole Derivatives with Potent Tubulin Polymerization Inhibiting Activity As Anticancer Agents Including Hedgehog-Dependent Cancer

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2013 Daniele Mazzà, Paola Infante, Valeria Colicchia, Azzura Greco, Romina Alfonsi

ORCID

, M. Siler, Laura Antonucci, Agnese Po, Enrico De Smaele, Elisabetta Ferretti, Carlo Capalbo, Diana Bellavia, Gianluca Canettieri, Giuseppe Giannini

ORCID

, Isabella Screpanti and 2 other authors

PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress

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