Lars Wortmann - Dissemin

All papers authored by Lars Wortmann

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2021 Lars Wortmann

, Simon J. Holton, Horst Irlbacher, Jörg Weiske, Christian Lechner, Robin Meier, Jakob Karén, Catrine Berthold Siöberg, Vera Pütter, Clara D. Christ

, Antonius ter Laak, Philip Lienau, Ralf Lesche, Barbara Nicke and 6 other authors

Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A

Upload

Markus Berger

, Lars Wortmann

, Philipp Buchgraber, Ulrich Lücking

, Sabine Zitzmann-Kolbe, Antje M. Wengner, Benjamin Bader, Ulf Bömer, Hans Briem, Knut Eis

, Hartmut Rehwinkel, Florian Bartels, Dieter Moosmayer, Uwe Eberspächer, Philip Lienau and 7 other authors

BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies

Upload

2020 Laura M. Luh, Ulrike Scheib, Katrin Juenemann, Lars Wortmann

, Michael Brands, Philipp M. Cromm

Beute für das Proteasom: Gezielter Proteinabbau aus medizinalchemischer Perspektive

Upload

Ulrich Lücking

, Lars Wortmann

, Antje M. Wengner, Julien Lefranc

, Philip Lienau, Hans Briem, Gerhard Siemeister, Ulf Bömer, Karsten Denner, Martina Schäfer, Marcus Koppitz, Knut Eis

, Florian Bartels

, Benjamin Bader, Wilhelm Bone and 8 other authors

Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models

Upload

This paper was not found in any repository, but could be made available legally by the author.

Giacomo Cossa, Isabelle Roeschert, Florian Prinz, Raphael Silveira Vidal, Christina Schülein-Völk, Yun-Chien Chang, Guido Mastrobuoni, Amit Kumar, Cyrille Girard, Lars Wortmann

, Apoorva Baluapuri

, Susanne Walz, Reinhard Lührmann, Carsten Patrick Ade, Stefan Kempa and 4 other authors

Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription

Upload

2019 Lars Wortmann

, Bernhard Lindenthal, Peter Muhn, Alexander Walter, Reinhard Nubbemeyer, Dieter Heldmann, Lothar Sobek, Federica Morandi, Anna K. Schrey, Dieter Moosmayer, Judith Günther, Joachim Kuhnke, Marcus Koppitz, Ulrich Lücking, Ulrike Röhn and 5 other authors

Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo

Upload

Antje M. Wengner, Gerhard Siemeister, Ulrich Lücking

, Julien Lefranc

, Lars Wortmann

, Philip Lienau, Benjamin Bader, Ulf Bömer, Dieter Moosmayer, Uwe Eberspächer, Sven Golfier, Christoph A. Schatz, Simon J. Baumgart, Bernard Haendler, Pascale Lejeune and 5 other authors

The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage–Inducing or Repair–Compromising Therapies in Preclinical Cancer Models

Upload

Roman C. Hillig, Brice Sautier, Jens Schroeder, Dieter Moosmayer, André Hilpmann, Christian M. Stegmann, Nicolas D. Werbeck, Hans Briem, Ulf Boemer, Joerg Weiske, Volker Badock, Julia Mastouri, Kirstin Petersen, Gerhard Siemeister, Jan D. Kahmann and 7 other authors

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction

Upload

2018 Duy Nguyen

, Clara Lemos, Lars Wortmann

, Knut Eis, Simon J. Holton, Ulf Boemer, Dieter Moosmayer, Uwe Eberspaecher, Joerg Weiske, Christian Lechner, Stefan Prechtl, Detlev Suelzle, Franziska Siegel, Florian Prinz, Ralf Lesche and 8 other authors

Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2-d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5

Upload

Daniel Hog, Robin Meier, Henriette Lämmermann, Alexander Sudau, Daniel Rackl, Hilmar Weinmann, Karl Collins, Lars Wortmann

, Lisa Candish

Late-Stage Sulfoximidation of Electron-Rich Arenes by Photoredox Catalysis

Upload

2016 Brice Sautier

, Carl F. Nising, Lars Wortmann

Fortschritte bei der Ras-Inhibition aus medizinisch-chemischer Perspektive

Upload

2013 Jayne L. Kenwright, Warren R. J. D. Galloway, Lars Wortmann

, David R. Spring

Mild and Efficient Synthesis of Benzo-Fused Seven- and Eight-membered Ring Lactams: A Convenient Approach to Biologically Interesting Chemotypes

Upload

This paper is available in a repository.

2011 Jayne L. Kenwright, Warren R. J. D. Galloway, David T. Blackwell, Albert Isidro-Llobet, James Hodgkinson

, Lars Wortmann

, Steven D. Bowden, Martin Welch, David R. Spring

Novel and Efficient Copper-Catalysed Synthesis of Nitrogen-Linked Medium-Ring Biaryls

Download from www.researchgate.net

This paper is made freely available by the publisher.

2007 Anna Santamaria, Rüdiger Neef, Uwe Eberspächer, Knut Eis, Manfred Husemann, Dominik Mumberg, Stefan Prechtl, Volker Schulze, Gerhard Siemeister, Lars Wortmann

, Francis A. Barr, Erich A. Nigg

Use of the Novel Plk1 Inhibitor ZK-Thiazolidinone to Elucidate Functions of Plk1 in Early and Late Stages of Mitosis

Download from www.molbiolcell.org

2004 Dieter Enders, Lars Wortmann

, Gerhard Raabe, Barbara Dücker

A Highly Flexible Route to 1,2,3,4,5,6- Hexahydro-5-hydroxypyrimidin-2-ones as Potential HIV Protease Inhibitors

Upload

2003 Frank Würthner, Stefan Bräse, Norbert Sewald, Rainer Herges, Matthias O. Senge, Thorsten Bach, Thomas Gottwald, Thomas Kopf, Kristina Ŝpehar, Jens Hartung, Dietmar Plattner, Andreas Gansäuer, Martin Oestreich, Reinhard Brückner, Jörg Pietruszka and 11 other authors

Organische Chemie 2002

Upload

2002 Dieter Enders, Lars Wortmann

Asymmetric Synthesis of 4,6-Disubstituted 1,2,3,4,5,6-Hexahydro-5-hydroxypyrimidin-2-ones as Potential HIV-Protease-Inhibitors

Upload

2000 Dieter Enders, Lars Wortmann

, René Peters

Recovery of Carbonyl Compounds from N,N-Dialkylhydrazones

Upload