All papers authored by Charles Lesburg
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2022
David A. Candito 
,
Vladimir Simov,
Anmol Gulati ,
Solomon Kattar ,
Ryan W. Chau,
Blair T. Lapointe,
Joey L. Methot ,
Duane E. DeMong,
Thomas H. Graham,
Ravi Kurukulasuriya,
Mitchell H. Keylor ,
Ling Tong ,
Gregori J. Morriello,
John J. Acton,
Barbara Pio
and 31 other authors
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,
Vladimir Simov,
Anmol Gulati ,
Solomon Kattar ,
Ryan W. Chau,
Blair T. Lapointe,
Joey L. Methot ,
Duane E. DeMong,
Thomas H. Graham,
Ravi Kurukulasuriya,
Mitchell H. Keylor ,
Ling Tong ,
Gregori J. Morriello,
John J. Acton,
Barbara Pio
and 31 other authors
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John A. McIntosh ,
Zhijian Liu,
Brian M. Andresen ,
Nastaran Salehi Marzijarani ,
Jeffrey C. Moore ,
Nicholas M. Marshall,
Margie Borra-Garske,
Jennifer V. Obligacion,
Patrick S. Fier,
Feng Peng,
Jacob H. Forstater,
Matthew S. Winston,
Chihui An,
Wonsuk Chang,
Jongwon Lim
and 46 other authors
,
Zhijian Liu,
Brian M. Andresen ,
Nastaran Salehi Marzijarani ,
Jeffrey C. Moore ,
Nicholas M. Marshall,
Margie Borra-Garske,
Jennifer V. Obligacion,
Patrick S. Fier,
Feng Peng,
Jacob H. Forstater,
Matthew S. Winston,
Chihui An,
Wonsuk Chang,
Jongwon Lim
and 46 other authors
A kinase-cGAS cascade to synthesize a therapeutic STING activator
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Derun Li,
David L. Sloman ,
Abdelghani Achab,
Hua Zhou,
Meredeth A. McGowan,
Catherine White ,
Craig Gibeau,
Hongjun Zhang ,
Qinglin Pu ,
Indu Bharathan,
Brett Hopkins,
Kun Liu,
Heidi Ferguson,
Xavier Fradera ,
Charles A. Lesburg
and 24 other authors
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,
Abdelghani Achab,
Hua Zhou,
Meredeth A. McGowan,
Catherine White ,
Craig Gibeau,
Hongjun Zhang ,
Qinglin Pu ,
Indu Bharathan,
Brett Hopkins,
Kun Liu,
Heidi Ferguson,
Xavier Fradera ,
Charles A. Lesburg
and 24 other authors
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2021
Mitchell H. Keylor ,
Anmol Gulati ,
Solomon D. Kattar,
Rebecca E. Johnson,
Ryan W. Chau,
Kaila A. Margrey,
Michael J. Ardolino ,
Cayetana Zarate,
Kelsey E. Poremba,
Vladimir Simov,
Gregori J. Morriello,
John J. Acton,
Barbara Pio,
Xin Yan ,
Rachel L. Palte
and 21 other authors
,
Anmol Gulati ,
Solomon D. Kattar,
Rebecca E. Johnson,
Ryan W. Chau,
Kaila A. Margrey,
Michael J. Ardolino ,
Cayetana Zarate,
Kelsey E. Poremba,
Vladimir Simov,
Gregori J. Morriello,
John J. Acton,
Barbara Pio,
Xin Yan ,
Rachel L. Palte
and 21 other authors
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors
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Derun Li ,
Hongjun Zhang ,
Thomas W. Lyons,
Min Lu ,
Abdelghani Achab,
Qinglin Pu ,
Matthew Childers,
Matthew J. Mitcheltree ,
Jialiang Wang,
Theodore A. Martinot ,
Spencer E. McMinn,
David L. Sloman ,
Anandan Palani,
Adam Beard,
Lisa Nogle
and 10 other authors
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,
Hongjun Zhang ,
Thomas W. Lyons,
Min Lu ,
Abdelghani Achab,
Qinglin Pu ,
Matthew Childers,
Matthew J. Mitcheltree ,
Jialiang Wang,
Theodore A. Martinot ,
Spencer E. McMinn,
David L. Sloman ,
Anandan Palani,
Adam Beard,
Lisa Nogle
and 10 other authors
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Brett Hopkins,
Hongjun Zhang ,
Indu Bharathan,
Derun Li ,
Qinglin Pu ,
Hua Zhou,
Theodore A. Martinot ,
Xavier Fradera ,
Alfred Lammens,
Charles A. Lesburg ,
Ryan D. Cohen ,
Jeanine Ballard,
Ian Knemeyer,
Karin Otte,
Stella Vincent
and 8 other authors
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,
Indu Bharathan,
Derun Li ,
Qinglin Pu ,
Hua Zhou,
Theodore A. Martinot ,
Xavier Fradera ,
Alfred Lammens,
Charles A. Lesburg ,
Ryan D. Cohen ,
Jeanine Ballard,
Ian Knemeyer,
Karin Otte,
Stella Vincent
and 8 other authors
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Derun Li ,
Yongqi Deng,
Abdelghani Achab,
Indu Bharathan,
Brett Andrew Hopkins ,
Wensheng Yu ,
Hongjun Zhang ,
Sulagna Sanyal,
Qinglin Pu ,
Hua Zhou,
Kun Liu,
Jongwon Lim ,
Xavier Fradera ,
Charles A. Lesburg ,
Alfred Lammens
and 25 other authors
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,
Yongqi Deng,
Abdelghani Achab,
Indu Bharathan,
Brett Andrew Hopkins ,
Wensheng Yu ,
Hongjun Zhang ,
Sulagna Sanyal,
Qinglin Pu ,
Hua Zhou,
Kun Liu,
Jongwon Lim ,
Xavier Fradera ,
Charles A. Lesburg ,
Alfred Lammens
and 25 other authors
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2020
Joey L. Methot ,
Abdelghani Achab,
Matthew Christopher,
Hua Zhou,
Meredeth A. McGowan,
B. Wesley Trotter,
Xavier Fradera ,
Charles A. Lesburg ,
Peter Goldenblatt,
Armetta Hill,
Dapeng Chen,
Karin M. Otte,
Martin Augustin,
Sanjiv Shah,
Jason D. Katz
,
Abdelghani Achab,
Matthew Christopher,
Hua Zhou,
Meredeth A. McGowan,
B. Wesley Trotter,
Xavier Fradera ,
Charles A. Lesburg ,
Peter Goldenblatt,
Armetta Hill,
Dapeng Chen,
Karin M. Otte,
Martin Augustin,
Sanjiv Shah,
Jason D. Katz
Optimization of Versatile Oxindoles as Selective PI3Kδ Inhibitors
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Bo-Sheng Pan ,
Samanthi A. Perera ,
Jennifer A. Piesvaux ,
Jeremy P. Presland ,
Gottfried K. Schroeder ,
Jared N. Cumming ,
B. Wesley Trotter ,
Michael D. Altman,
Alexei V. Buevich ,
Brandon Cash ,
Saso Cemerski ,
Wonsuk Chang ,
Yiping Chen,
Peter J. Dandliker ,
Guo Feng
and 26 other authors
,
Samanthi A. Perera ,
Jennifer A. Piesvaux ,
Jeremy P. Presland ,
Gottfried K. Schroeder ,
Jared N. Cumming ,
B. Wesley Trotter ,
Michael D. Altman,
Alexei V. Buevich ,
Brandon Cash ,
Saso Cemerski ,
Wonsuk Chang ,
Yiping Chen,
Peter J. Dandliker ,
Guo Feng
and 26 other authors
An orally available non-nucleotide STING agonist with antitumor activity
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Zahid Hussain,
Andrew J. Cooke,
Santhosh Neelamkavil,
Lindsay Brown,
Emma Carswell,
Wayne M. Geissler,
Zhuyan Guo,
Brian Hawes,
Terri M. Kelly,
Yasuko Kiyoi,
KehDih Lai,
Charles Lesburg ,
Eleanor Pow,
Yi Zang,
Harold B. Wood
and 2 other authors
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,
Eleanor Pow,
Yi Zang,
Harold B. Wood
and 2 other authors
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