Helge Dorfmueller

All papers authored by Helge Dorfmueller

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2021 Sowmya Ajay Castro, Sarah Thomson, Azul Zorzoli, Benjamin H. Meyer

, Mark Reglinski, Helge C. Dorfmueller

Recombinant Group A Carbohydrate backbone embedded into Outer Membrane Vesicles is a potent vaccine candidate targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

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Benjamin H. Meyer

, Ben A. Wagstaff, Panagiotis S. Adam, Sonja-Verena Albers, Helge C. Dorfmueller

N-glycan chitobiose core biosynthesis by Agl24 strengthens the hypothesis of an archaeal origin of the eukaryal N-glycosylation

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D. W. Arends

, W. R. Miellet, J. D. Langereis

, T. H. A. Ederveen, C. E. van der Gaast–de Jongh, M. van Scherpenzeel, M. J. Knol, N. M. van Sorge, D. J. Lefeber, K. Trzciński, E. A. M. Sanders, H. C. Dorfmueller

, H. J. Bootsma, M. I. de Jonge

Examining the Distribution and Impact of Single-Nucleotide Polymorphisms in the Capsular Locus of Streptococcus pneumoniae Serotype 19A

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Harley King, Sowmya Ajay Castro, Amol Arunrao Pohane, Cynthia M. Scholte, Vincent A. Fischetti, Natalia Korotkova, Daniel C. Nelson, Helge C. Dorfmueller

Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin

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This paper is made freely available by the publisher.

Sowmya Ajay Castro

, Helge C. Dorfmueller

A brief review on Group A Streptococcus pathogenesis and vaccine development

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Ben A. Wagstaff, Azul Zorzoli, Helge C. Dorfmueller

NDP-rhamnose biosynthesis and rhamnosyltransferases: building diverse glycoconjugates in nature

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2020 Megan D. Lenardon, Prashant Sood, Helge C. Dorfmueller

, Alistair J. P. Brown, Neil A. R. Gow

Scalar nanostructure of the Candida albicans cell wall; a molecular, cellular and ultrastructural analysis and interpretation

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2019 Azul Zorzoli

, Benjamin H. Meyer, Elaine Adair, Vladimir I. Torgov, Vladimir V. Veselovsky, Leonid L. Danilov, Dusan Uhrin, Helge C. Dorfmueller

Group A, B, C, and G Streptococcus Lancefield antigen biosynthesis is initiated by a conserved α-d-GlcNAc-β-1,4-l-rhamnosyltransferase

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2018 Samantha L. van der Beek, Azul Zorzoli

, Ebru Çanak, Robert N. Chapman, Kieron Lucas, Benjamin H. Meyer

, Dimitrios Evangelopoulos, Luiz Pedro S. de Carvalho, Geert-Jan P. H. Boons

, Helge C. Dorfmueller

, Nina M. van Sorge

Streptococcal dTDP-L-rhamnose biosynthesis enzymes: functional characterization and lead compound identification

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2014 Helge Christian Dorfmueller

, Andrew T. Ferenbach, Vladimir S. Borodkin, Daan M. F. van Aalten

A Structural and Biochemical Model of Processive Chitin Synthesis*

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Vladimir S. Borodkin, Daan M. F. vanAalten, Daan Mf F. van Aalten, Marianne Schimpl

, Mehmet Gundogdu, Karim Rafie, Helge Christian Dorfmueller

, Daan M. F. van Aalten, David A. Robinson

Bisubstrate UDP–peptide conjugates as human O-GlcNAc transferase inhibitors

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2013 Francesco V. Rao, Alexander W. Schüttelkopf, Helge C. Dorfmueller

, Andrew T. Ferenbach, Iva Navratilova, Daan M. F. van Aalten

Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

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2012 Helge C. Dorfmueller

, Wenxia Fang, Francesco V. Rao, David E. Blair, Helen Attrill

, Daan M. F. van Aalten

Structural and biochemical characterization of a trapped coenzyme A adduct ofCaenorhabditis elegansglucosamine-6-phosphateN-acetyltransferase 1

Download from www.ncbi.nlm.nih.gov

2010 Helge C. Dorfmueller

, Vladimir S. Borodkin, Marianne Schimpl

, Xiaowei Zheng, Robert Kime, Kevin D. Read, Daan M. F. van Aalten

Cell-Penetrant, Nanomolar O-GlcNAcase Inhibitors Selective against Lysosomal Hexosaminidases

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Helge C. Dorfmueller

, Vladimir S. Borodkin, David E. Blair, Shalini Pathak, Iva Navratilova, Daan M. F. van Aalten

Substrate and product analogues as human O-GlcNAc transferase inhibitors

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2009 Helge C. Dorfmueller

, Vladimir S. Borodkin, Marianne Schimpl

, Daan M. F. van Aalten

GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation

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2008 Ramon Hurtado-Guerrero, Helge C. Dorfmueller

, Daan Mf F. van Aalten

Molecular mechanisms of O-GlcNAcylation

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Shalini Pathak, Helge C. Dorfmueller

, Vladimir S. Borodkin, Daan M. F. van Aalten

Chemical Dissection of the Link between Streptozotocin, O-GlcNAc, and Pancreatic Cell Death

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2006 Helge C. Dorfmueller

, Vladimir S. Borodkin, Marianne Schimpl

, Sharon M. Shepherd, Natalia A. Shpiro, Daan M. F. van Aalten

GlcNAcstatin: a Picomolar, Selective O-GlcNAcase Inhibitor That Modulates Intracellular O-GlcNAcylation Levels

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All papers authored by Helge Dorfmueller