Roger Frigério Castilho

All papers authored by Roger Frigério Castilho

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2024 Annelise Francisco

, Ayse Mine Yilmaz Goler, Claudia Daniele Carvalho Navarro, Asan Onder

, Melek Yildiz

, Yasemin Kendir Demirkol

, Betul Karademir Yilmaz, Tuba Seven Menevse

, Tülay Güran

, Roger Frigério Castilho

Lack of NAD(P)+ transhydrogenase activity in patients with primary adrenal insufficiency due to NNT variants

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2021 Annelise Francisco

, Tiago Rezende Figueira, Roger Frigério Castilho

Mitochondrial NAD(P)+ Transhydrogenase: From Molecular Features to Physiology and Disease

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Tiago R. Figueira

, Annelise Francisco

, Juliana A. Ronchi, Guilherme R. R. M. dos Santos, William dos Santos

, Jason R. Treberg, Roger F. Castilho

NADPH supply and the contribution of NAD(P)+ transhydrogenase (NNT) to H2O2 balance in skeletal muscle mitochondria

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Marina Rincon Sartori

, J. Lerchner

, R. F. Castilho

, P. O. Volpe, F. Mertens, A. E. Vercesi

Chip-calorimetric assessment of heat generation during Ca2+ uptake by digitonin-permeabilized Trypanosoma cruzi

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Tiago R. Figueira

, Annelise Francisco, Jason R. Treberg, Roger F. Castilho

Can NAD(P)+ transhydrogenase (NNT) mediate a physiologically meaningful increase in energy expenditure by mitochondria during H2O2 removal?

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2020 Rafaela Bicego, Annelise Francisco

, Juliana S. Ruas

, Edilene S. Siqueira-Santos, Roger F. Castilho

Undesirable effects of chemical inhibitors of NAD(P)+ transhydrogenase on mitochondrial respiratory function

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Annelise Francisco

, Daiane F. Engel, Tiago R. Figueira, Fábio Rogério, Andreza F. de Bem, Roger F. Castilho

Mitochondrial NAD(P)+ Transhydrogenase is Unevenly Distributed in Different Brain Regions, and its Loss Causes Depressive-like Behavior and Motor Dysfunction in Mice

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Ana Cristina Roginski, Alessandro Wajner, Cristiane Cecatto, Simone Magagnin Wajner, Roger Frigério Castilho

, Moacir Wajner, Alexandre Umpierrez Amaral

Disturbance of bioenergetics and calcium homeostasis provoked by metabolites accumulating in propionic acidemia in heart mitochondria of developing rats

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Cristiane Cecatto, Alexandre Umpierrez Amaral, Ana Cristina Roginski, Róger Frigério Castilho

, Moacir Wajner

Impairment of mitochondrial bioenergetics and permeability transition induction caused by major long-chain fatty acids accumulating in VLCAD deficiency in skeletal muscle as potential pathomechanisms of myopathy

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Cristiane Cecatto, Alexandre Umpierrez Amaral, Alessandro Wajner, Simone Magagnin Wajner, Roger Frigério Castilho

, Moacir Wajner

Disturbance of mitochondrial functions associated with permeability transition pore opening induced by cis-5-tetradecenoic and myristic acids in liver of adolescent rats

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2019 Ana Cristina Roginski, Cristiane Cecatto, Simone Magagnin Wajner, Fernanda Dal’Maso Camera, Roger Frigério Castilho

, Moacir Wajner, Alexandre Umpierrez Amaral

Experimental evidence that maleic acid markedly compromises glutamate oxidation through inhibition of glutamate dehydrogenase and α-ketoglutarate dehydrogenase activities in kidney of developing rats

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2018 Pedro H. L. Bonfitto, Ana C. Antunes Naime, M. Elisa Lopes-Pires, Gisele Goulart, Camila B. Mendes-Silverio, Paulo I. Bueno, Roger F. Castilho

, Edson Antunes, Sisi Marcondes

Platelet activity is negatively modulated by tumor necrosis factor alpha through reductions of cytosolic calcium levels and integrin alphaIIbbeta3 phosphorylation

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Anibal E. Vercesi, Roger F. Castilho

, Alicia J. Kowaltowski, Helena C. F. de Oliveira, Nadja C. de Souza-Pinto, Tiago R. Figueira

, Estela N. B. Busanello

Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition

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This paper is made freely available by the publisher.

Juliana S. Ruas, Edilene S. Siqueira-Santos, Erika Rodrigues-Silva, Roger F. Castilho

High glycolytic activity of tumor cells leads to underestimation of electron transport system capacity when mitochondrial ATP synthase is inhibited

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Annelise Francisco

, Juliana A. Ronchi, Claudia D. C. Navarro, Tiago R. Figueira

, Roger F. Castilho

Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high‐fat diet

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Cristiane Cecatto, Alexandre Umpierrez Amaral, Janaína Camacho Silva, Alessandro Wajner, Mariana de Oliveira Vargas Schimit, Lucas Henrique Rodrigues Silva, Simone Magagnin Wajner, Ângela Zanatta, Roger Frigério Castilho

, Moacir Wajner

Metabolite accumulation inVLCADdeficiency markedly disrupts mitochondrial bioenergetics and Ca2+homeostasis in the heart

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2017 Claudia D. C. Navarro, Tiago R. Figueira

, Annelise Francisco

, Genoefa A. Dal'Bó, Juliana A. Ronchi, Juliana C. Rovani, Cecilia A. F. Escanhoela, Helena C. F. Oliveira, Roger F. Castilho

, Anibal E. Vercesi

Redox imbalance due to the loss of mitochondrial NAD(P)-transhydrogenase markedly aggravates high fat diet-induced fatty liver disease in mice

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Gustavo Facchini, Raffaela Silvestre Ignarro, Erika Rodrigues-Silva, André Schwambach Vieira, Iscia Lopes-Cendes, Roger Frigério Castilho

, Fabio Rogerio

Toxic effects of phytol and retinol on human glioblastoma cells are associated with modulation of cholesterol and fatty acid biosynthetic pathways

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Evellyne de Oliveira Figueirôa, Mary Ângela Aranda-Souza, Nathalia Varejão, Franco Aparecido Rossato, Rute Alves Pereira Costa, Tiago Rezende Figueira

, Luís Cláudio Nascimento da Silva

, Roger Frigério Castilho

, Aníbal Eugênio Vercesi, Maria Tereza dos Santos Correia

pCramoll and rCramoll lectins induce cell death in human prostate adenocarcinoma (PC-3) cells by impairment of mitochondrial homeostasis

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Erika Rodrigues-Silva, Edilene S. Siqueira-Santos, Juliana S. Ruas, Raffaela S. Ignarro, Tiago R. Figueira

, Fábio Rogério, Roger F. Castilho

Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity

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All papers authored by Roger Frigério Castilho