Richard Ward - Dissemin

All papers authored by Richard Ward

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2021 Nicola Colclough, Kan Chen, Peter Johnström, Nicole Strittmatter

, Yumei Yan, Gail L. Wrigley, Magnus Schou, Richard Goodwin

, Katarina Varnäs, Sally J. Adua, Minghui Zhao, Don X. Nguyen, Gareth Maglennon, Peter Barton, James Atkinson

and 20 other authors

Preclinical Comparison of the Blood–brain barrier Permeability of Osimertinib with Other EGFR TKIs

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2020 Richard A. Ward

, Stephen Fawell, Nicolas Floc’h, Vikki Flemington, Darren McKerrecher, Paul D. Smith

Challenges and Opportunities in Cancer Drug Resistance

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Kirsten McAulay, Emily A. Hoyt

, Morgan Thomas, Marianne Schimpl

, Michael Steven Bodnarchuk

, Hilary Jane Lewis

, Derek Barratt, Deepa Bhavsar, David M. Robinson, Michael J. Deery, Derek J. Ogg, Gonçalo J. L. Bernardes

, Richard A. Ward

, Michael J. Waring

, Jason Grant Kettle

Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors

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Xiang Zhai

, Richard A. Ward

, Peter Doig, Argyrides Argyrou

Insight into the Therapeutic Selectivity of the Irreversible EGFR Tyrosine Kinase Inhibitor Osimertinib through Enzyme Kinetic Studies

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2019 Richard A. Ward

, Mark J. Anderton, Paul Bethel, Jason Breed, Calum Cook, Emma J. Davies, Andrew Dobson, Zhiqiang Dong, Gary Fairley, Paul Farrington, Lyman Feron, Vikki Flemington, Francis D. Gibbons, Mark A. Graham, Ryan Greenwood and 23 other authors

Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC)

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This paper is made freely available by the publisher.

Iva Lukac

, Hend Abdelhakim

, Richard A. Ward

, Stephen A. St-Gallay

, Judith C. Madden

, Andrew G. Leach

Predicting protein–ligand binding affinity and correcting crystal structures with quantum mechanical calculations: lactate dehydrogenase A

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2017 Jonathan D. Wrigley

, Gerald Gavory, Iain Simpson, Marian Preston, Helen Plant, Jenna Bradley, Anne U. Goeppert, Ewelina Rozycka, Gareth Davies, Jarrod Walsh, Andrea Valentine, Keeva McClelland, Krzysztofa Ewa Odrzywol, Jonathan Renshaw, Joanna Boros and 6 other authors

Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily

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Richard Lonsdale

, Jonathan Burgess, Nicola Colclough, Nichola L. Davies, Eva M. Lenz, Alexandra L. Orton, Richard A. Ward

Expanding the Armory: Predicting and Tuning Covalent Warhead Reactivity

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Richard A. Ward

, Paul Bethel, Calum Cook, Emma Davies, Judit E. Debreczeni, Gary Fairley, Lyman Feron, Vikki Flemington, Mark A. Graham, Ryan Greenwood, Nicola Griffin, Lyndsey Hanson, Philip Hopcroft, Tina D. Howard, Julian Hudson and 14 other authors

Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point

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All papers authored by Richard Ward