Valerie Sim - Dissemin

All papers authored by Valerie Sim

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2021 Leonardo M. Cortez

, Satish K. Nemani

, Camilo Duque Velásquez, Aishwarya Sriraman

, YongLiang Wang, Holger Wille

, Debbie McKenzie

, Valerie L. Sim

Asymmetric-flow field-flow fractionation of prions reveals a strain-specific continuum of quaternary structures with protease resistance developing at a hydrodynamic radius of 15 nm

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Hailey Pineau, Valerie L. Sim

From Cell Culture to Organoids-Model Systems for Investigating Prion Strain Characteristics

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2020 Satish K. Nemani, Jennifer L. Myskiw, Lise Lamoureux, Stephanie A. Booth, Valerie L. Sim

Exposure Risk of Chronic Wasting Disease in Humans

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Kristina Jeon, Jeffrey T. Joseph, Gerard H. Jansen

, Anne Peterson, J. David Knox, Valerie L. Sim

Creutzfeldt–Jakob Disease with a Five-Year Clinical Course, Multicentric Cerebellar Prion Plaques and Prior History of Biopsy-Proven Primary Angiitis of the Central Nervous System: A Case for Iatrogenic Exposure?

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Hailey Pineau, Valerie Sim

POSCAbilities: The Application of the Prion Organotypic Slice Culture Assay to Neurodegenerative Disease Research

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This paper was not found in any repository, but could be made available legally by the author.

2018 B. V. Foroutanpay, J. Kumar, S. G. Kang, N. Danaei, D. Westaway, V. L. Sim

, S. Kar

The Effects of N-terminal Mutations on β-amyloid Peptide Aggregation and Toxicity

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2016 Amar Nath Gupta, Krishna Neupane

, Negar Rezajooei, Leonardo M. Cortez, Valerie L. Sim

, Michael T. Woodside

Pharmacological chaperone reshapes the energy landscape for folding and aggregation of the prion protein

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Emily Mostofi, Wouter I. Schievink, Valerie L. Sim

Dural Reduction Surgery: A Treatment Option for Frontotemporal Brain Sagging Syndrome

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Sang-Gyun Kang, Chiye Kim, Leonardo M. Cortez, María Carmen Garza, Jing Yang, Holger Wille, Valerie L. Sim

, David Westaway, Debbie McKenzie, Judd Aiken

Toll-like receptor-mediated immune response inhibits prion propagation

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2015 Jitendra Kumar, Risa Namsechi, Valerie L. Sim

Structure-Based Peptide Design to Modulate Amyloid Beta Aggregation and Reduce Cytotoxicity

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Leonardo M. Cortez, Jody Campeau, Grant Norman, Marian Kalayil, Jacques Van der Merwe, Debbie McKenzie, Valerie L. Sim

Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Samia Hannaoui, Barbara Killy, Stefanie Czub, Valerie Sim

, Sabine Gilch

Biochemical properties of chronic wasting disease prions and relationship with prion shedding

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Jitendra Kumar, Stephanie Czub, Sabine Gilch, Valerie Sim

Profiling infectious elk prion protein distribution based on size using asymmetrical flow field-flow fractionation

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Sang-Gyun Kang, Chiye Kim, Leonardo M. Cortez, Jing Yang, Maria Carmen Garza, Holger Wille, Valerie L. Sim

, David Westaway, Debbie McKenzie, Judd Aiken

Neuroprotective role of innate immunity in prion infection

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M. Carmen Garza, Pamela Banser, Leonardo Cortez, Jacques van der Merwe, David A. Kramer, Nathalie Daude, Richard Fahlman, Valerie Sim

, David Westaway, Judd Aiken, Debbie McKenzie, Holger Wille

Myotube cultures as a prion source for structural investigations

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2014 Leonardo Cortez, Valerie Sim

The therapeutic potential of chemical chaperones in protein folding diseases

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Patrick Walsh, Gillian Vanderlee, Jason Yau, Jody Campeau, Valerie L. Sim

, Christopher M. Yip, Simon Sharpe

The Mechanism of Membrane Disruption by Cytotoxic Amyloid Oligomers Formed by Prion Protein(106–126) Is Dependent on Bilayer Composition*

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Penelope Smyth, Valerie Sim

Objective Structured Clinical Examination (OSCE) Station on Communicating Poor Prognosis to the Family in a Neurological Acute Care Setting

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Jody L. Campeau, Grant Norman, Debbie McKenzie, Valerie L. Sim

Adaptation of prion-infected brain organotypic cultures to other species and brain regions

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Jitendra Kumar, Valerie Sim

D-amino acid-based peptide inhibitors as early or preventative therapy in Alzheimer disease

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All papers authored by Valerie Sim