Willem Joost Lesterhuis - Dissemin

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All papers authored by Willem Joost Lesterhuis

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2021 Jeroen H. A. Creemers

ORCID

, I. Jolanda M. de Vries

ORCID

, W. Joost Lesterhuis

ORCID

ORCID

, Winald R. Gerritsen

ORCID

, Carl G. Figdor

ORCID

, I. Jolanda M. de Vries, Johannes Textor

ORCID

A tipping point in cancer-immune dynamics leads to divergent immunotherapy responses and hampers biomarker discovery

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Nicola Principe, Joel Kidman, Richard A. Lake, Willem Joost Lesterhuis

ORCID

, Anna K. Nowak, Alison M. McDonnell, Jonathan Chee

Malignant Pleural Effusions—A Window Into Local Anti-Tumor T Cell Immunity?

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2020 Nicola Principe, Joel Kidman, Siting Goh, Caitlin M. Tilsed, Scott A. Fisher, Vanessa S. Fear, Catherine A. Forbes, Rachael M. Zemek, Abha Chopra, Mark Watson, Ian M. Dick, Louis Boon, Robert A. Holt, Richard A. Lake, Anna K. Nowak and 3 other authors

Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy

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Joel Kidman, Nicola Principe, Mark Watson, Timo Lassmann, Robert A. Holt, Anna K. Nowak, Willem Joost Lesterhuis

ORCID

, Richard A. Lake, Jonathan Chee

Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

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Anna K. Nowak, W. Joost Lesterhuis

ORCID

, Peey-Sei Kok, Chris Brown

ORCID

, Brett Gm Hughes, Deme J. Karikios, Thomas John, Steven C.-H. Kao, Connull Leslie, Alistair M. Cook, Nick Pavlakis, Karen Briscoe, Kenneth J. O'Byrne, Christos S. Karapetis, Wei-Sen Lam and 3 other authors

Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM): a multicentre, single-arm, phase 2 trial with a safety run-in

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Francois X. Rwandamuriye, Breana J. Weston, Terrance G. Johns, W. Joost Lesterhuis

ORCID

, Rachael M. Zemek

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

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Rachael M. Zemek

ORCID

, Vanessa S. Fear, Cath Forbes, Emma de Jong, Thomas H. Casey

ORCID

, Louis Boon, Timo Lassmann

ORCID

, Anthony Bosco, Michael J. Millward, Anna K. Nowak

ORCID

, Richard A. Lake, W. Joost Lesterhuis

ORCID

Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

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Rachael M. Zemek, Wee Loong Chin, Anna K. Nowak, Michael J. Millward, Richard A. Lake, W. Joost Lesterhuis

ORCID

Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy

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Steve Boudewijns

ORCID

, Martine Bloemendal

ORCID

, Nienke de Haas

ORCID

, Harm Westdorp

ORCID

, Kalijn F. Bol

ORCID

, Gerty Schreibelt

ORCID

, Erik H. J. G. Aarntzen

ORCID

, W. Joost Lesterhuis

ORCID

, Mark A. J. Gorris

ORCID

, Alexandra Croockewit, Lieke L. van der Woude, Michelle M. van Rossum, Marieke Welzen, Anna de Goede, Stanleyson V. Hato and 6 other authors

Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial

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2019 Rachael M. Zemek

ORCID

ORCID

, Wee Loong Chin, Iona S. Schuster, Vanessa S. Fear, Thomas H. Casey

ORCID

, Cath Forbes, Sarah J. Dart

ORCID

, Connull Leslie, Ayham Zaitouny, Michael Small, Louis Boon

ORCID

, Alistair R. R. Forrest

ORCID

, Daithi O. Muiri, Mariapia A. Degli-Esposti

ORCID

and 6 other authors

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

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Wayne J. Aston

ORCID

, Danika E. Hope

ORCID

, Alistair M. Cook

ORCID

ORCID

, Ian Dick

ORCID

, Anna K. Nowak

ORCID

, Richard A. Lake

ORCID

, W. Joost Lesterhuis

ORCID

Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment

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Wee Loong Chin

ORCID

, Rachael M. Zemek

ORCID

, W. Joost Lesterhuis

ORCID

, Timo Lassmann

ORCID

Functional genomics in cancer immunotherapy: computational approaches for biomarker and drug discovery

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2018 Jonathan Chee

ORCID

, Mark W. Watson, Abha Chopra, Bella Nguyen, Alistair M. Cook, Jenette Creaney, Willem J. Lesterhuis

ORCID

, Bruce W. Robinson, Y. C. Gary Lee, Anna K. Nowak, Richard A. Lake, Alison M. McDonnell

Tumour associated lymphocytes in the pleural effusions of patients with mesothelioma express high levels of inhibitory receptors

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2017 Wayne J. Aston, Danika E. Hope, Anna K. Nowak, Bruce W. Robinson, Richard A. Lake, W. Joost Lesterhuis

ORCID

A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice

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Eva A. Ebbing, Anne Steins, Evelyn Fessler, Phylicia Stathi, Willem Joost Lesterhuis

ORCID

, Kausilia K. Krishnadath, Louis Vermeulen, Jan Paul Medema, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven

Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition

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Stanleyson V. Hato, Carl G. Figdor, Susumu Takahashi, Anja E. Pen, Altuna Halilovic, Kalijn F. Bol

ORCID

, Angela Vasaturo

ORCID

, Yukie Inoue, Nienke de Haas, Dagmar Verweij, Carla M. L. Van Herpen, Johannes H. Kaanders, Johan H. J. M. van Krieken

ORCID

, Hanneke W. M. Van Laarhoven, Gerrit K. J. Hooijer

ORCID

and 4 other authors

Direct inhibition of STAT signaling by platinum drugs contributes to their anti-cancer activity

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W. Joost Lesterhuis

ORCID

, Anthony Bosco, Michael J. Millward, Michael Small, Anna K. Nowak, Richard A. Lake

Dynamic versus static biomarkers in cancer immune checkpoint blockade: unravelling complexity

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2016 Scott A. Fisher, Wayne J. Aston, Jonathan Chee

ORCID

, Andrea Khong, Amanda L. Cleaver, Jessica N. Solin, Shaokang Ma, W. Joost Lesterhuis

ORCID

, Ian Dick, Robert A. Holt, Jenette Creaney, Louis Boon, Bruce Robinson, Richard A. Lake

Transient Treg depletion enhances therapeutic anti‐cancer vaccination

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Alistair M. Cook

ORCID

, W. Joost Lesterhuis

ORCID

, Anna K. Nowak, Richard A. Lake

Chemotherapy and immunotherapy: mapping the road ahead

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