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All papers authored by Thomas Hunt

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2018 Stephen T. Durant

ORCID

, Li Zheng

ORCID

, Yingchun Wang, Kan Chen, Lingli Zhang, Tianwei Zhang, Zhenfan Yang, Lucy Riches, Antonio G. Trinidad, Jacqueline H. L. Fok

ORCID

, Tom Hunt

ORCID

, Kurt G. Pike, Joanne Wilson, Aaron Smith, Nicola Colclough and 23 other authors

The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models

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Steve T. Durant, Kurt G. Pike, Nicola Colclough, Lucy Riches, Antonio Garcia-Trinidad, Thomas Hunt

ORCID

, Stephanie Ling, Jonathan Stott, Ian Barrett, Li Zheng, Yingchun Wang, Kan Chen, Tianwei Zhang, Venkatesh Pilla Reddy, Andrew Sykes and 9 other authors

Abstract A104: AZD1390, a potent and selective orally bioavailable blood-brain barrier-penetrant ATM inhibitor, radiosensitizes and improves survival of orthotopic glioma and metastatic brain tumor models

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2015 Rebecca Butler, Thomas Hunt

ORCID

, Nichola J. Smith

ENaC inhibitors for the treatment of cystic fibrosis

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2012 Thomas Hunt

ORCID

, Hazel C. Atherton-Watson, Stephen P. Collingwood, Kevin J. Coote, Sarah Czarnecki, Henry Danahay, Catherine Howsham, Peter Hunt, Derek Paisley, Alice Young

Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 2: α-Branched quaternary amines

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Thomas Hunt

ORCID

, Hazel C. Atherton-Watson, Jake Axford, Stephen P. Collingwood, Kevin J. Coote, Brian Cox, Sarah Czarnecki, Henry Danahay, Nick Devereux, Catherine Howsham, Peter Hunt, Victoria Paddock, Derek Paisley, Alice Young

Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 1: Quaternary amines

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2006 Thomas A. Hunt

ORCID

, Andrew F. Parsons, Robert Pratt

A diastereoselective radical cyclization approach to substituted quinuclidines

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Cheryl L. Hill, Gideon Grogan, Matthew McGrath, T. Hunt

ORCID

A Generic and Reproducible Route to Homo- and Heteroannular Bicyclic β-Diketones via Knochel-Type 1,4-Conjugate Additions to α,β-Unsaturated Cycloalkenones

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2005 Thomas Hunt

ORCID

, Andrew F. Parsons, Robert Pratt

Radion Reactions To Form Vinylphosphonothioates

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