Heledd Jarosz-Griffiths

All papers authored by Heledd Jarosz-Griffiths

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2019 Samuel Lara-Reyna, Thomas Scambler, Jonathan Holbrook, Chi Wong, Heledd H. Jarosz-Griffiths

, Fabio Martinon, Sinisa Savic, Daniel Peckham, Michael F. McDermott

Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation

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H. Jarosz-Griffiths

, T. Scambler, S. Lara-Reyna, J. Holbrook, C. Wong, S. Pathak, F. Martinon, S. Savic, M. F. McDermott, D. Peckham

ePS1.09 Inhibition of autoinflammation in cystic fibrosis using small molecule therapy

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Heledd H. Jarosz-Griffiths

, Nicola J. Corbett, Helen A. Rowland, Kate Fisher, Alys C. Jones, Jennifer Baron, Gareth J. Howell, Sally A. Cowley, Satyan Chintawar

, M. Zameel Cader

, Katherine A. B. Kellett, Nigel M. Hooper

Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers

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Heledd H. Jarosz-Griffiths

, Jonathan Holbrook, Samuel Lara-Reyna, Michael F. McDermott

TNF receptor signalling in autoinflammatory diseases

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Jonathan Holbrook, Samuel Lara-Reyna, Heledd Jarosz-Griffiths

, Michael F. McDermott

Tumour necrosis factor signalling in health and disease

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2018 Thomas Scambler, Heledd H. Jarosz-Griffiths

, Samuel Lara-Reyna, Shelly Pathak, Chi Wong, Jonathan Holbrook, Fabio Martinon, Sinisa Savic

, Daniel Peckham, Michael F. McDermott

Excessive ENaC-mediated sodium influx drives NLRP3 inflammasome-dependent autoinflammation in Cystic Fibrosis

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Samuel Lara-Reyna, Thomas Scambler, Jonathan Holbrook, Heledd H. Jarosz-Griffiths

, Daniel Peckham, Michael F. McDermott

Regulation of the Unfolded Protein Response in Disease: Cellular Stress and microRNAs

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2017 Katherine J. Sellers, Christina Elliott, Joshua Jackson, Anshua Ghosh, Elena Ribe, Ana I. Rojo, Heledd H. Jarosz-Griffiths

, Iain A. Watson, Weiming Xia, Mikhail Semenov, Peter Morin, Nigel M. Hooper, Rod Porter, Jane Preston, Raya Al-Shawi and 7 other authors

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil

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2015 Heledd H. Jarosz Griffiths

, Elizabeth Noble, Jo V. Rushworth, Nigel M. Hooper

Amyloid-β receptors: the good, the bad and the prion protein

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2014 N. T. Hettiarachchi, M. L. Dallas, M. M. Al-Owais, H. H. Griffiths

, N. M. Hooper, J. L. Scragg, J. P. Boyle, C. Peers

Heme oxygenase-1 protects against Alzheimer's amyloid-β1-42-induced toxicity via carbon monoxide production

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Nicole T. Watt, Heledd H. Griffiths

, Nigel M. Hooper

Lipid rafts: linking prion protein to zinc transport and amyloid-Î² toxicity in Alzheimer's disease

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Jo V. Rushworth, Asif Ahmed, Heledd H. Griffiths

, Niall M. Pollock, Nigel M. Hooper, Paul A. Millner

A label-free electrical impedimetric biosensor for the specific detection of Alzheimer's amyloid-beta oligomers

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2013 Nicole T. Watt, Heledd H. Griffiths

, Nigel M. Hooper

Neuronal zinc regulation and the prion protein

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Jo V. Rushworth, Heledd H. Griffiths

, Nicole T. Watt, Nigel M. Hooper

Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1*

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2012 Heledd H. Griffiths

, Isobel J. Whitehouse, Nigel M. Hooper

Regulation of amyloid-β production by the prion protein

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Nicole T. Watt, David R. Taylor, Talitha L. Kerrigan, Heledd H. Griffiths

, Jo V. Rushworth, Isobel J. Whitehouse, Nigel M. Hooper

Prion protein facilitates uptake of zinc into neuronal cells

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2011 Heledd H. Griffiths

, Isobel J. Whitehouse, Herbert Baybutt, Debbie Brown, Katherine A. B. Kellett, Carolyn D. Jackson, Anthony J. Turner, Pedro Piccardo, Jean C. Manson, Nigel M. Hooper

Prion Protein Interacts with BACE1 Protein and Differentially Regulates Its Activity toward Wild Type and Swedish Mutant Amyloid Precursor Protein*

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2008 R. Smith, R. D. O. Jones, P. G. Ballard, H. H. Griffiths

Determination of microsome and hepatocyte scaling factors forin vitro/in vivoextrapolation in the rat and dog

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Heledd H. Griffiths

, Isobel J. Morten, Nigel M. Hooper

Emerging and potential therapies for Alzheimer's disease

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All papers authored by Heledd Jarosz-Griffiths