P. Ross Wilderman

All papers authored by P. Ross Wilderman

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2016 Manish B. Shah, Hyun-Hee Jang, P. Ross Wilderman

, David Lee, Sheng Li, Qinghai Zhang, C. David Stout, James R. Halpert

Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry

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Jingbao Liu, Manish B. Shah, Qinghai Zhang, C. David Stout, James Robert Halpert, P. Ross Wilderman

Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations

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2015 Hyun-Hee Jang, Jingbao Liu, Ga-Young Lee, James R. Halpert, P. Ross Wilderman

Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes

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Manish B. Shah, P. Ross Wilderman

, Jingbao Liu, Hyun-Hee Jang, Qinghai Zhang, C. David Stout, James R. Halpert

Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison

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2013 P. Ross Wilderman

, Hyun-Hee Jang, Jael R. Malenke, Mariam Salib, Elizabeth Angermeier, Sonia Lamime

, M. Denise Dearing, James R. Halpert

Functional characterization of cytochromes P450 2B from the desert woodrat Neotoma lepida

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P. Ross Wilderman

, Manish B. Shah, Hyun-Hee Jang, C. David Stout, James R. Halpert

Structural and Thermodynamic Basis of (+)-α-Pinene Binding to Human Cytochrome P450 2B6

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2012 Manish B. Shah, P. Ross Wilderman

, Jaime Pascual, Qinghai H. Zhang, C. David Stout, James R. Halpert

Conformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed Upon Binding Multiple Amlodipine Molecules⊥

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P. Ross Wilderman

, James R. Halpert

Plasticity of CYP2B Enzymes: Structural and Solution Biophysical Methods

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P. Ross Wilderman

, Hyun-Hee Jang, Elizabeth Angermeier, Jael R. Malenke, M. Denise Dearing, James R. Halpert

Functional Characterization of Cytochromes P450 2B from Woodrats

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Hyun-Hee Jang, P. Ross Wilderman

, Deepak Dalvie, James R. Halpert

Functional analysis of cytochrome P450 2B isoforms using ticlopidine as an active site probe

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2011 Sean C. Gay, Haoming Zhang, P. Ross Wilderman

, Arthur G. Roberts, Tong Liu, Sheng Li, Hsia-Lien Lin, Qinghai Zhang, Virgil L. Woods, C. David Stout, Paul F. Hollenberg, James R. Halpert

Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivatortert-Butylphenylacetylene: Insight into Partial Enzymatic Activity

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2010 P. Ross Wilderman

, Manish B. Shah, Tong Liu, Sheng Li, Simon Hsu, Arthur G. Roberts, David R. Goodlett, Qinghai Zhang, Virgil L. Woods, C. David Stout, James R. Halpert

Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography*

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Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, P. Ross Wilderman

, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout, C. David Stout, James R. Halpert

Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution

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S. C. Gay, M. B. Shah, J. C. Talakad, K. Maekawa, A. G. Roberts, P. R. Wilderman

, L. Sun, J. Y. Yang, S. C. Huelga, Q. H. Zhang, C. D. Stout, J. R. Halpert

Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl) imidazole at 2.0 angstrom Resolution

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Paul Ross Wilderman

, Sean Gay, Arthur Roberts, Sheng Li, Tong Liu, Virgil Woods, James Halpert

Ligand-Induced Conformational Changes in Cytochrome P450 2B4: A Multi-Technique Approach

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Jyothi C. Talakad, P. Ross Wilderman

, Dmitri R. Davydov, Santosh Kumar, James R. Halpert

Structural importance of residue 334 in the stability of cytochromes P450 2B6 and 2B11

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2009 Jyothi C. Talakad, P. Ross Wilderman

, P. Ross Wilderman, Dmitri R. Davydov, Santosh Kumar, James R. Halpert

Rational Engineering of Cytochromes P450 2B6 and 2B11 for Enhanced Stability: Insights Into Structural Importance of Residue 334

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2007 P. Ross Wilderman

, Reuben J. Peters

A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase

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Arnab Roy, Frank G. Roberts, P. Ross Wilderman

, Ke Zhou, Reuben J. Peters, Robert M. Coates

16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: Potent Mechanism-Based Inhibitors of Recombinantent-Kaurene Synthase fromArabidopsis thaliana

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Anthony Cyr, P. Ross Wilderman

, Mara Determan, Reuben J. Peters

A Modular Approach for Facile Biosynthesis of Labdane-Related Diterpenes

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All papers authored by P. Ross Wilderman