Siew Yeen Chai - Dissemin

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All papers authored by Siew Yeen Chai

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2018 Sudarsana Reddy Vanga, Jonas Sävmarker, Leelee Ng, Mats Larhed

ORCID

, Mathias Hallberg, Johan Åqvist

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, Anders Hallberg, Siew Yeen Chai

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, Hugo Gutiérrez-De-Terán

ORCID

Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides

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2017 Yijun Pan

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, Kwok H. C. Choy, Philip J. Marriott

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, Siew Y. Chai

ORCID

, Martin J. Scanlon, Christopher J. H. Porter, Jennifer L. Short, Joseph A. Nicolazzo

ORCID

Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets

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Anthony L. Albiston, Mauricio Cacador, Puspha Sinnayah, Peta Burns, Siew Yeen Chai

ORCID

Insulin-regulated aminopeptidase inhibitors do not alter glucose handling in normal and diabetic rats

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2016 Holly R. Yeatman, Anthony L. Albiston, Peta Burns, Siew Yeen Chai

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Forebrain neurone-specific deletion of insulin-regulated aminopeptidase causes age related deficits in memory

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Shanti Diwakarla, Erik Nylander, Alfhild Grönbladh, Sudarsana Reddy Vanga, Yasmin Shamsudin Khan, Yasmin Shamsudin, Hugo Gutiérrez-De-Terán, Jonas Sävmarker, Leelee Ng, Vi Pham, Thomas Lundbäck, Annika Jenmalm-Jensen, Richard Svensson, Per Artursson, Sofia Zelleroth and 6 other authors

Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures

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Benjamin Seyer

ORCID

, Vi Pham, Anthony L. Albiston, Siew Yeen Chai

ORCID

Cannula implantation into the lateral ventricle does not adversely affect recognition or spatial working memory

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Shanti Diwakarla, Erik Nylander, Alfhild Grönbladh, Sudarsana Reddy Vanga, Yasmin Shamsudin Khan, Hugo Gutiérrez-De-Terán, Leelee Ng, Vi Pham, Jonas Sävmarker, Thomas Lundbäck, Annika Jenmalm-Jensen, Hanna Andersson, Karin Engen, Ulrika Rosenström, Mats Larhed and 3 other authors

Binding to and Inhibition of Insulin-Regulated Aminopeptidase by Macrocyclic Disulfides Enhances Spine Density

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2015 D. De Bundel, De Bundel Dimitri, Assia Fafouri, Zsolt Csaba, Ellen Loyens, Sophie Lebon, V. El Ghouzzi, Vincent El Ghouzzi, Stéphane Peineau, Guilan Vodjdani, Foteini Kiagiadaki, Najat Aourz, Jessica Coppens, Laura Walrave, Jeanelle Portelli and 9 other authors

Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures

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2014 Stefan J. Hermans, David B. Ascher, Nancy C. Hancock, Jessica K. Holien, Belinda J. Michell, Siew Yeen Chai

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, Craig J. Morton, Michael W. Parker

ORCID

Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides

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Simon J. Mountford, Anthony L. Albiston, William N. Charman, Leelee Ng, Jessica K. Holien, Michael W. Parker, Joseph A. Nicolazzo, Philip E. Thompson, Siew Yeen Chai

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Synthesis, Structure–Activity Relationships and Brain Uptake of a Novel Series of Benzopyran Inhibitors of Insulin-Regulated Aminopeptidase

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Alexandros Nikolaou, Benoit Stijlemans

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, Damya Laoui, Elio Schouppe, Huyen Tt Tran, Dirk Tourwe, Siew Y. Chai

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, Patrick Ml Vanderheyden, Jo A. Van Ginderachter

Presence and regulation of insulin-regulated aminopeptidase in mouse macrophages

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2013 Ellen Loyens, S. Yeen Chai, Dimitri De Bundel, Heidi Demaegdt, Siew Yeen Chai

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, Patrick Vanderheyden, Yvette Michotte, Paul Gard, Ilse Smolders

Antidepressant-like effects of oxytocin in mice are dependent on the presence of insulin-regulated aminopeptidase

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2012 Vi Pham, Anthony L. Albiston, Catherine E. Downes, Connie H. Y. Wong

ORCID

, Shanti Diwakarla, Leelee Ng, Seyoung Lee, Peter J. Crack

ORCID

, Siew Yeen Chai

ORCID

Insulin-Regulated Aminopeptidase Deficiency Provides Protection against Ischemic Stroke in Mice

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2011 Anthony L. Albiston, Shanti Diwakarla, Ruani N. Fernando, Simon J. Mountford, Holly R. Yeatman, Broden Morgan, Vi Pham, Jessica K. Holien, Michael W. Parker, Philip E. Thompson, Siew Yeen Chai

ORCID

Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers

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David B. Ascher, Brett A. Cromer, Craig J. Morton, Irene Volitakis, Robert A. Cherny, Anthony L. Albiston, Siew Yeen Chai

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, Michael W. Parker

Regulation of Insulin-Regulated Membrane Aminopeptidase Activity by Its C-Terminal Domain

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E. Loyens, A. Schallier, Siew Y. Chai

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, Dimitri De Bundel, Patrick Vanderheyden, Yvette Michotte, Ilse Smolders

Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures

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Anthony L. Albiston, Holly R. Yeatman, Vi Pham, Stephanie J. Fuller, Shanti Diwakarla, Ruani N. Fernando, Siew Yeen Chai

ORCID

Distinct distribution of GLUT4 and insulin regulated aminopeptidase in the mouse kidney

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Rui Yang, Ilse Smolders, Patrick Vanderheyden, Heidi Demaegdt, Ann Van Eeckhaut

ORCID

, Georges Vauquelin, Aneta Lukaszuk, Dirk Tourwe, Siew Yeen Chai

ORCID

, Anthony L. Albiston, Clara Nahmias, Thomas Walther, Alain G. Dupont

Pressor and renal hemodynamic effects of the novel angiotensin A peptide are angiotensin II type 1A receptor dependent

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Broden J. Morgan, Siew Yeen Chai, Siew Yeen Chai

ORCID

, Anthony L. Albiston, Anthony Albiston

GLUT4 Associated Proteins as Therapeutic Targets for Diabetes

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2010 Anthony L. Albiston, Vi Pham, Siying Ye, Leelee Ng, Rebecca A. Lew, Philip E. Thompson, Jessica K. Holien, Craig J. Morton, Michael W. Parker, Siew Yeen Chai

ORCID

Phenylalanine-544 Plays a Key Role in Substrate and Inhibitor Binding by Providing a Hydrophobic Packing Point at the Active Site of Insulin-Regulated Aminopeptidase

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