Claudio Grosman - Dissemin

All papers authored by Claudio Grosman

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2020 Pramod Kumar

, Yuhang Wang

, Zhening Zhang, Zhiyu Zhao

, Gisela D. Cymes

, Emad Tajkhorshid

, Claudio Grosman

Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer

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2019 Tyler J. Harpole, Claudio Grosman

A Crucial Role for Side-Chain Conformation in the Versatile Charge Selectivity of Cys-Loop Receptors

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2016 Gisela D. Cymes, Claudio Grosman

Identifying the elusive link between amino acid sequence and charge selectivity in pentameric ligand-gated ion channels

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2015 Giovanni Gonzalez-Gutierrez, Claudio Grosman

The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold

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Gisela D. Cymes, Claudio Grosman

Engineered Ionizable Side Chains

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2014 Tyler J. Harpole, Claudio Grosman

Side-chain conformation at the selectivity filter shapes the permeation free-energy landscape of an ion channel

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David Papke, Claudio Grosman

The Role of Intracellular Linkers in Gating and Desensitization of Human Pentameric Ligand-Gated Ion Channels

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2013 Giovanni Gonzalez-Gutierrez, Luis G. Cuello, Satish K. Nair, Claudio Grosman

Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography

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2012 Gisela D. Cymes, Claudio Grosman

The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors

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Giovanni Gonzalez-Gutierrez, Tiit Lukk, Vinayak Agarwal, David Papke, Satish K. Nair, Claudio Grosman

Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals

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2011 Gisela D. Cymes, Claudio Grosman

Estimating the pKa values of basic and acidic side chains in ion channels using electrophysiological recordings: A robust approach to an elusive problem

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Gisela D. Cymes, Claudio Grosman

Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors

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David Papke, Giovanni Gonzalez-Gutierrez, Claudio Grosman

Desensitization of neurotransmitter-gated ion channels during high-frequency stimulation: a comparative study of Cys-loop, AMPA and purinergic receptors

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2010 Giovanni Gonzalez-Gutierrez, Claudio Grosman

Bridging the gap between structural models of nicotinic-receptor superfamily ion channels and their corresponding functional states

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2009 Sergio Elenes, Michael Decker, Gisela D. Cymes, Claudio Grosman

Response to the Letter: “About a new method to measure fractional Ca2+ currents through ligand-gated ion channels”

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Sergio Elenes, Michael Decker, Gisela D. Cymes, Claudio Grosman

Decremental Response to High-Frequency Trains of Acetylcholine Pulses but Unaltered Fractional Ca2+ Currents in a Panel of “Slow-Channel Syndrome” Nicotinic Receptor Mutants

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2008 Gisela D. Cymes, Claudio Grosman

Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer

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2006 Sergio Elenes, Ying Ni, Gisela D. Cymes, Claudio Grosman

Desensitization Contributes to the Synaptic Response of Gain-of-Function Mutants of the Muscle Nicotinic Receptor

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Yamini Purohit, Claudio Grosman

Block of Muscle Nicotinic Receptors by Choline Suggests that the Activation and Desensitization Gates Act as Distinct Molecular Entities

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Yamini Purohit, Claudio Grosman

Estimating Binding Affinities of the Nicotinic Receptor for Low-efficacy Ligands Using Mixtures of Agonists and Two-dimensional Concentration–Response Relationships

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All papers authored by Claudio Grosman