Leonard Schalkwyk - Dissemin

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All papers authored by Leonard Schalkwyk

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2021 Rebecca G. Smith, Ehsan Pishva

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, Gemma Shireby, Adam R. Smith

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, Janou A. Y. Roubroeks, Eilis Hannon

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, Gregory Wheildon, Diego Mastroeni

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, Gilles Gasparoni

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, Matthias Riemenschneider, Armin Giese, Andrew J. Sharp

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, Leonard Schalkwyk

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, Vahram Haroutunian

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, Wolfgang Viechtbauer

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and 13 other authors

A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex

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2019 Louis Y. El Khoury, Tyler Gorrie-Stone, Melissa Smart, Amanda Hughes, Yanchun Bao, Alexandria Andrayas, Joe Burrage, Eilis Hannon

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, Meena Kumari, Jonathan Mill, Leonard C. Schalkwyk

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Systematic underestimation of the epigenetic clock and age acceleration in older subjects

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2018 Eilis Hannon

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, Tyler J. Gorrie-Stone

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, Melissa C. Smart

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, Joe Burrage, Amanda Hughes, Yanchun Bao

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, Meena Kumari, Leonard C. Schalkwyk

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, Jonathan Mill

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Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits.

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2015 Helen Spiers, Eilis Hannon

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, Leonard C. Schalkwyk

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, Rebecca Smith, Chloe C. Y. Wong, Michael C. O'Donovan, Nicholas J. Bray, Jonathan Mill

Methylomic trajectories across human fetal brain development

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Charlotte Martin, Katherine E. Tansey, Leonard C. Schalkwyk

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, Timothy R. Powell

The inflammatory cytokines: molecular biomarkers for major depressive disorder?

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Marco P. M. Boks, Hans C. van Mierlo

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, Lot de Witte, Hans C. van Mierlo, Bart P. F. Rutten, Timothy R. D. J. Radstake, Lot D. De Witte, Timothy . D J. Radstake, Elbert Geuze

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, Steve Horvath, Leonard C. Schalkwyk

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, Christiaan H. Vinkers, Jasper C. A. Broen

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, Eric Vermetten

Longitudinal changes of telomere length and epigenetic age related to traumatic stress and post-traumatic stress disorder

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2014 Karim Malki, Oliver Pain, Ebba Du Rietz, Maria Grazia Tosto, Jose Paya-Cano, Kenneth N. Sandnabba, Sietse de Boer, Leonard C. Schalkwyk

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, Frans Sluyter

Genes and Gene Networks Implicated in Aggression Related Behaviour

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Katie Lunnon, Rebecca Smith, Eilis Hannon

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, Philip L. De Jager, Gyan Srivastava, Manuela Volta, Claire Troakes

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, Safa Al-Sarraj, Joe Burrage, Ruby Macdonald, Daniel Condliffe, Lorna W. Harries, Pavel Katsel, Vahram Haroutunian, Zachary Kaminsky and 6 other authors

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

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Daniel Condliffe, Andrew Wong, Claire Troakes

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, Petroula Proitsi, Yogen Patel, Leonidas Chouliaras, Cathy Fernandes, Jonathan Cooper, Simon Lovestone, Leonard C. Schalkwyk

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, Jonathan Mill, Katie Lunnon

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Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain

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Timothy R. Powell, Peter McGuffin, Ursula M. D'Souza, Sarah Cohen-Woods, Georgina M. Hosang

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, Charlotte Martin, Keith Matthews, Richard K. Day, Anne E. Farmer, Katherine E. Tansey, Leonard C. Schalkwyk

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Putative Transcriptomic Biomarkers in the Inflammatory Cytokine Pathway Differentiate Major Depressive Disorder Patients from Control Subjects and Bipolar Disorder Patients

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Nicholas E. Ilott, Tomasz Schneider, Jonathan Mill, Leonard C. Schalkwyk

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, Giovana Brolese, Lisiane Bizarro, Ian P. Stolerman, Emma Dempster, Philip Asherson

Long-Term Effects of Gestational Nicotine Exposure and Food-Restriction on Gene Expression in the Striatum of Adolescent Rats

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Timothy R. Powell, Georgia Powell-Smith, Kate Haddley, Peter McGuffin, John Quinn, Leonard C. Schalkwyk

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, Anne E. Farmer, Ursula M. D'Souza

Mood-stabilizers differentially affect housekeeping gene expression in human cells: Housekeeping Gene Expression

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J. T. Bell, A. K. Loomis, L. M. Butcher, F. Gao, B. Zhang, C. L. Hyde, J. Sun, H. Wu, Kourosh R. Ahmadi, K. Ward, Chrysanthi Ainali, Amy Barrett, J. Harris, Veronique Bataille, S. Scollen and 50 other authors

Differential methylation of the TRPA1 promoter in pain sensitivity

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Joana Viana, Ruth Pidsley, Claire Troakes

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, Helen Spiers, Chloe Cy Wong, Safa Al-Sarraj, Ian Craig, Leonard C. Schalkwyk

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, Jonathan Mill

Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain

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Rebecca G. Smith, Cathy Fernandes, Rachel Kember, Leonard C. Schalkwyk

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, Joseph Buxbaum, Abraham Reichenberg, Jonathan Mill

Transcriptomic changes in the frontal cortex associated with paternal age

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Karim Malki, Robert Keers, Maria Grazia Tosto, Anbarasu Lourdusamy, Lucia Carboni, Enrico Domenici, Rudolf Uher, Peter McGuffin, Leonard C. Schalkwyk

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The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder

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Ruth Pidsley, Joana Viana, Eilis Hannon

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, Helen H. Spiers, Claire Troakes

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, Safa Al-Saraj, Naguib Mechawar, Gustavo Turecki, Schalkwyk Lc, Leonard C. Schalkwyk

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, Nicholas J. Bray, Bray Nj, Jonathan Mill

Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

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2013 Karim Malki, Maria Grazia Tosto, Irfan Jumabhoy, Anbarasu Lourdusamy, Frans Sluyter, Ian Craig, Rudolf Uher, Peter McGuffin, Leonard C. Schalkwyk

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Integrative mouse and human mRNA studies using WGCNA nominates novel candidate genes involved in the pathogenesis of major depressive disorder

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Timothy R. Powell, R. G. Smith, S. Hackinger, Leonard C. Schalkwyk

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, Rudolf Uher, Peter McGuffin, J. Mill, Katherine E. Tansey

DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP

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Timothy R. Powell, Katherine E. Tansey, Gerome Breen, Anne E. Farmer, Ian W. Craig, Rudolf Uher, Peter McGuffin, Ursula M. D'Souza, Leonard C. Schalkwyk

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ATP-binding cassette sub-family F member 1 (ABCF1) is identified as a putative therapeutic target of escitalopram in the inflammatory cytokine pathway

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