Hiromichi Ebi - Dissemin

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All papers authored by Hiromichi Ebi

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2024 Hideaki Bando

ORCID

, Kyoko Yamaguchi

ORCID

, Seiichiro Mitani, Kentaro Sawada, Saori Mishima

ORCID

, Keigo Komine, Yoshinaga Okugawa, Waki Hosoda

ORCID

, Hiromichi Ebi

ORCID

Japanese Society of Medical Oncology clinical guidelines: Molecular testing for colorectal cancer treatment, 5th edition

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2023 Yuta Adachi

ORCID

, Ryo Kimura, Kentaro Hirade, Shogo Yanase, Yuki Nishioka, Natsumi Kasuga, Rui Yamaguchi

ORCID

, Hiromichi Ebi

ORCID

Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS

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2021 Yoshiaki Nakamura, Wataru Okamoto, Takeshi Kato, Taito Esaki, Ken Kato

ORCID

, Yoshito Komatsu

ORCID

, Satoshi Yuki, Toshiki Masuishi, Tomohiro Nishina, Hiromichi Ebi

ORCID

, Kentaro Sawada, Hiroya Taniguchi, Nozomu Fuse, Shogo Nomura, Makoto Fukui and 12 other authors

Circulating tumor DNA-guided treatment with pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer: a phase 2 trial

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2020 Yuta Adachi, Kenatro Ito

ORCID

, Yuko Hayashi, Ryo Kimura, Tuan Zea Tan

ORCID

, Rui Yamaguchi, Hiromichi Ebi

ORCID

Epithelial to mesenchymal transition is a cause of both intrinsic and acquired resistance to KRAS G12C inhibitor in KRAS G12C mutant non-small cell lung cancer

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2016 Hidenori Kitai, Hiromichi Ebi

ORCID

Key roles of EMT for adaptive resistance to MEK inhibitor in KRAS mutant lung cancer

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Hidenori Kitai, Hiromichi Ebi

ORCID

, Shuta Tomida, Konstantinos V. Floros, Hiroshi Kotani, Yuta Adachi, Satoshi Oizumi, Masaharu Nishimura, Anthony C. Faber, Seiji Yano

Epithelial-to-Mesenchymal Transition Defines Feedback Activation of Receptor Tyrosine Kinase Signaling Induced by MEK Inhibition in KRAS-Mutant Lung Cancer

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Azusa Tanimoto, Shinji Takeuchi, Hiroshi Yaegashi, Hiroshi Kotani, Hidenori Kitai, Shigeki Nanjo, Kaname Yamashita, Hisatsugu Mouri, Hiromichi Ebi

ORCID

, Koushiro Ohtsubo, Hiroko Ikeda, Seiji Yano

Recurrence of renal cell carcinoma diagnosed using contralateral adrenal biopsy with endoscopic ultrasound-guided fine-needle aspiration

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2015 Shigeki Nanjo, Hiromichi Ebi

ORCID

, Sachiko Arai, Shinji Takeuchi, Tadaaki Yamada

ORCID

, Satsuki Mochizuki, Yasunori Okada, Mitsutoshi Nakada, Takashi Murakami, Seiji Yano

High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells

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Anthony C. Faber, Anna F. Farago, Carlotta Costa, Anahita Dastur, Maria Gomez-Caraballo, Rebecca Robbins, Bethany L. Wagner, William M. Rideout, Charles T. Jakubik, Jungoh Ham, Elena J. Edelman, Hiromichi Ebi

ORCID

, Alan T. Yeo, Aaron N. Hata, Youngchul Song and 15 other authors

Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer

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Hiromichi Ebi

ORCID

, Isao Oze, Takayuki Nakagawa, Hidemi Ito, Satoyo Hosono, Fumihiko Matsuda, Meiko Takahashi, Shinji Takeuchi, Yukinori Sakao, Toyoaki Hida, Anthony C. Faber, Hideo Tanaka, Yasushi Yatabe

ORCID

, Tetsuya Mitsudomi, Seiji Yano and 1 other authors

Lack of Association between the BIM Deletion Polymorphism and the Risk of Lung Cancer with and without EGFR Mutations

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H. Ebi

ORCID

Treatment strategies targeting lung cancer harboring KRAS or BRAF mutations

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2014 Carlotta Costa, Hiromichi Ebi

ORCID

, Miriam Martini

ORCID

, Sean A. Beausoleil, Anthony C. Faber, Charles T. Jakubik, Alan Huang, Youzhen Wang, Madhuri Nishtala, Ben Hall, Klarisa Rikova, Jean Zhao, Emilio Hirsch, Cyril H. Benes, Jeffrey A. Engelman

Measurement of PIP3 Levels Reveals an Unexpected Role for p110β in Early Adaptive Responses to p110α-Specific Inhibitors in Luminal Breast Cancer

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Azusa Tanimoto, Tadaaki Yamada

ORCID

, Shigeki Nanjo, Shinji Takeuchi, Hiromichi Ebi

ORCID

, Kenji Kita, Kunio Matsumoto, Seiji Yano

Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells

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Junya Nakade, Shinji Takeuchi, Takayuki Nakagawa, Daisuke Ishikawa, Takako Sano, Shigeki Nanjo, Tadaaki Yamada

ORCID

, Hiromichi Ebi

ORCID

, Lu Zhao, Kazuo Yasumoto, Kunio Matsumoto, Kazuhiko Yonekura, Seiji Yano

Triple Inhibition of EGFR, Met, and VEGF Suppresses Regrowth of HGF-Triggered, Erlotinib-Resistant Lung Cancer Harboring an EGFR Mutation

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2013 Shigeki Nanjo, Tadaaki Yamada

ORCID

, S. Nanjp, Hiroshi Nishihara, Shinji Takeuchi, Takako Sano, Lu Zhao, Takayuki Nakagawa, Daisuke Ishikawa, Kazuo Yasumoto, Hiromichi Ebi

ORCID

, Kunio Matsumoto, Seiji Yano

Ability of the Met Kinase Inhibitor Crizotinib and New Generation EGFR Inhibitors to Overcome Resistance to EGFR Inhibitors

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Hiromichi Ebi

ORCID

, Carlotta Costa, Anthony C. Faber, Madhuri Nishtala, Hiroshi Kotani, Dejan Juric, Patricia Della Pelle, Youngchul Song, Seiji Yano, Mari Mino-Kenudson, Cyril H. Benes, Jeffrey A. Engelman

PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1

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Anthony C. Faber, Erin M. Coffee, Carlotta Costa, Anahita Dastur, Hiromichi Ebi

ORCID

, Aaron N. Hata, Alan T. Yeo, Elena J. Edelman, Youngchul Song, Ah Ting Tam, Jessica L. Boisvert, Randy J. Milano, Jatin Roper, David P. Kodack, Rakesh K. Jain and 6 other authors

mTOR Inhibition Specifically Sensitizes Colorectal Cancers with KRAS or BRAF Mutations to BCL-2/BCL-XL Inhibition by Suppressing MCL-1

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Daisuke Ishikawa, Shinji Takeuchi, Takayuki Nakagawa, Takako Sano, Junya Nakade, Shigeki Nanjo, Tadaaki Yamada

ORCID

, Hiromichi Ebi

ORCID

, Lu Zhao, Kazuo Yasumoto, Takahiro Nakamura, Kunio Matsumoto, Hiroshi Kagamu, Hirohisa Yoshizawa, Seiji Yano

mTOR Inhibitors Control the Growth of EGFR Mutant Lung Cancer Even after Acquiring Resistance by HGF

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Takayuki Nakagawa, Shinji Takeuchi, Hiromichi Ebi

ORCID

, Tadaaki Yamada

ORCID

, Takako Sano, Shigeki Nanjo, Daisuke Ishikawa, Mitsuo Sato, Yoshinori Hasegawa, Yoshitaka Sekido, Seiji Yano

EGFR-TKI Resistance Due to BIM Polymorphism Can Be Circumvented in Combination with HDAC Inhibition

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2012 Ryan B. Corcoran, Katherine A. Cheng, Aaron N. Hata, Hiromichi Ebi

ORCID

, Anthony C. Faber, Erin M. Coffee, Patricia Greninger, Ronald D. Brown, Jason T. Godfrey, Travis J. Cohoon, Youngchul Song, Eugene Lifshits, Kenneth E. Hung, Toshi Shioda, Dora Dias-Santagata and 6 other authors

Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models

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