David Gervais - Dissemin

All papers authored by David Gervais

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2020 David Gervais

Acidic isoforms of Erwinase form part of the product: Correlation with clinical experience

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2019 Angela Beckett

, David Gervais

What makes a good new therapeutic l-asparaginase?

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David Gervais

Quality Control and Downstream Processing of Therapeutic Enzymes

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2018 Charlotte Orphanou, David Gervais

Higher-order structure and conformational change in biopharmaceuticals

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2017 David Gervais

, Andrew Downer, Darryl King, Patrick Kanda, Nicholas Foote, Stuart Smith

Robust quantitation of basic-protein higher-order aggregates using size-exclusion chromatography

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David Gervais

, Justin Hayzen, Charlotte Orphanou, Alexandra McEntee, Christine Hallam, Rossalyn Brehm

Understanding the process-induced formation of minor conformational variants of Erwinia chrysanthemi l-asparaginase

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2015 David Gervais

Protein deamidation in biopharmaceutical manufacture: understanding, control and impact

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Michael J. McCluskie, Jennifer Thorn, David P. Gervais

, David R. Stead, Ningli Zhang, Michelle Benoit, Janna Cartier, In-Jeong Kim, Keshab Bhattacharya, Jari I. Finneman, James R. Merson, Heather L. Davis

Anti-nicotine vaccines: Comparison of adjuvanted CRM 197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates

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David Gervais

, Darryl King, Patrick Kanda, Nicholas Foote, Lucy Elliott, Phillip Brown

, Natacha O. Lee, Konstantinos Thalassinos, Claire Pizzey, Robert Rambo, Thomas C. Minshull, Mark J. Dickman, Stuart Smith

Structural Characterisation of Non-Deamidated Acidic Variants of Erwinia chrysanthemi L-asparaginase Using Small-Angle X-ray Scattering and Ion-Mobility Mass Spectrometry

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2014 David Gervais

, Darryl King

Capillary isoelectric focusing of a difficult-to-denature tetrameric enzyme using alkylurea–urea mixtures

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David Gervais

, Nicholas Foote

Recombinant Deamidated Mutants of Erwinia chrysanthemi l-Asparaginase Have Similar or Increased Activity Compared to Wild-Type Enzyme

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David Gervais

, Tim Corn, Andrew Downer, Stuart Smith, Alan Jennings

Measurement of Subvisible Particulates in Lyophilised Erwinia chrysanthemi l-asparaginase and Relationship with Clinical Experience

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2013 David C. Pryde, Lyn H. Jones, David P. Gervais

, David R. Stead, David C. Blakemore, Matthew D. Selby, Alan D. Brown, Jotham W. Coe, Matthew Badland, David M. Beal, Rebecca Glen, Yvonne Wharton, Gavin J. Miller, Phil White, Ningli Zhang and 6 other authors

Selection of a Novel Anti-Nicotine Vaccine: Influence of Antigen Design on Antibody Function in Mice

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David Gervais

, Jennifer O’Donnell, Mei-An Sung, Stuart Smith

Control of process-induced asparaginyl deamidation during manufacture of Erwinia chrysanthemi l-asparaginase

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Michael J. McCluskie, David C. Pryde, David P. Gervais

, David R. Stead, Ningli Zhang, Michelle Benoit, Karen Robertson, In-Jeong Kim, Tharsika Tharmanathan, James R. Merson, Heather L. Davis

Enhancing immunogenicity of a 3′aminomethylnicotine-DT-conjugate anti-nicotine vaccine with CpG adjuvant in mice and non-human primates

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2012 David Gervais

, Nigel Allison, Alan Jennings, Shane Jones, Trevor Marks

Validation of a 30-year-old process for the manufacture of l-asparaginase from Erwinia chrysanthemi

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1995 David P. Gervais

, W. Scott Laughinghouse, Giorgio Carta

Study of radial compression high-performance liquid chromatographic columns for preparative chromatography

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All papers authored by David Gervais