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All papers authored by Andrea Testa

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2023 Alessio Ciulli

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, Suzanne O'Connor

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, Chun‐Wa Chung, Ingo V. Hartung

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, Andrea Testa

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, Danette L. Daniels

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, Laura H. Heitman

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The 17^th EFMC Short Course on Medicinal Chemistry on Small Molecule Protein Degraders

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2021 Chiara Tarantelli

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, Eleonora Cannas, Hillarie Ekeh, Carmelo Moscatello

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, Eugenio Gaudio, Luciano Cascione

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, Cesare Rech, Andrea Testa

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, Chiara Maniaci

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, Andrea Rinaldi, Emanuele Zucca

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, Anastasios Stathis, Alessio Ciulli

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, Francesco Bertoni

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The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type

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Kristin M. Riching

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, James D. Vasta

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, Scott J. Hughes, Vittoria Zoppi, Chiara Maniaci

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, Andrea Testa

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, Alessio Ciulli

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, Danette L. Daniels

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Translating PROTAC chemical series optimization into functional outcomes underlying BRD7 and BRD9 protein degradation

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2020 Luke M. Simpson

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, Thomas J. Macartney, Alice Nardin

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, Luke J. Fulcher

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, Sascha Röth, Andrea Testa

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, Chiara Maniaci

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, Alessio Ciulli

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, Ian G. Ganley, Gopal P. Sapkota

Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System

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Andrea Testa

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ORCID

, Alessio Ciulli

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Stereoselective synthesis of allele-specific BET inhibitors

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2019 Hannah Tovell

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, Andrea Testa

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, Chiara Maniaci

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, Houjiang Zhou, Alan R. Prescott, Thomas Macartney, Alessio Ciulli

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, Dario R. Alessi

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Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC Degrader

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2018 Vittoria Zoppi, Scott J. Hughes, Chiara Maniaci

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, Andrea Testa

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, Teresa Gmaschitz, Corinna Wieshofer, Manfred Koegl, Kristin M. Riching, Danette L. Daniels

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, Andrea Spallarossa, Alessio Ciulli

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Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7

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Andrea Testa

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, Marco Mingarelli, Lutz Schweiger, Andrew Welch

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, Charles S. Elmore

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, Pradeep Sharma

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, Sergio Dall’Angelo, Matteo Zanda

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, Andrea Augello

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Preclinical Evaluation of [18F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters

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Andrea Testa

ORCID

ORCID

, Guilherme V. Castro, Kwok-Ho Chan, Jane E. Wright, Andrew C. Runcie, Morgan S. Gadd, William T. A. Harrison, Eun-Jung Ko

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, Daniel Fletcher, Alessio Ciulli

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3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation

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