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Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2
UploadHuman T-bet governs the generation of a distinct subset of CD11c high CD21 low B cells
UploadThe expansion of human T-bet high CD21 low B cells is T cell dependent
UploadActivated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production
Download from rupress.orgGermline-activating mutations in PIK3CD compromise B cell development and function
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