Pascal Kienlen-Campard

All papers authored by Pascal Kienlen-Campard

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2018 Caroline Evrard, Pascal Kienlen-Campard

, Mathilde Coevoet, Rémi Opsomer, Bernadette Tasiaux, Patricia Melnyk, Jean-Noël Octave, Luc Buée

Contribution of the endosomal-lysosomal and proteasomal systems in Amyloid-β Precursor Protein derived fragments processing

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2017 Serena Stanga, Céline Vrancx, Bernadette Tasiaux, Claudia Marinangeli, Helena Karlström, Pascal Kienlen-Campard

Specificity of presenilin-1- and presenilin-2-dependent γ-secretases towards substrate processing

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Anna Doshina, Florian Gourgue, Michiho Onizuka, Remi Opsomer, Peng Wang, Kunie Ando, Bernadette Tasiaux, Ilse Dewachter, Pascal Kienlen-Campard

, Jean-Pierre Brion, Philippe Gailly, Jean-Noël Octave, Nathalie Pierrot

Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

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Peng Wang, Gerard Joberty, Arjan Buist, Alexandre Vanoosthuyse, Ilie-Cosmin Stancu, Bruno Barbosa de Vasconcelos, Bruno Vasconcelos, Nathalie Pierrot, Maria Faelth-Savitski, Pascal Kienlen-Campard

, Jean-Noël Octave, Marcus Bantscheff, Gerard Drewes, Diederik Moechars, Ilse Dewachter

Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.

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2016 Julien Couturier, Ilie-Cosmin Stancu, Olivier Schakman, Nathalie Pierrot, François Huaux, Pascal Kienlen-Campard

, Ilse Dewachter, Jean-Noël Octave

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

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Bruno Barbosa de Vasconcelos, Bruno Vasconcelos, Ilie-Cosmin Stancu, Arjan Buist, Matthew Bird, Peng Wang, Alexandre Vanoosthuyse, Kristof Van Kolen, An Verheyen, Pascal Kienlen-Campard

, Jean-Noël Octave, Peter Baatsen, Diederik Moechars, Ilse Dewachter

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

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Marie Decock, Serena Stanga, Jean-Noël Octave, Ilse Dewachter, Steven O. Smith, Stefan N. Constantinescu, Pascal Kienlen-Campard

Glycines from the APP GXXXG/GXXXA transmembrane motifs promote formation of pathogenic AB oligomers in cells

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2015 Ilie-Cosmin Stancu, Bruno Barbosa de Vasconcelos, Bruno Vasconcelos, Laurence Ris, Peng Wang, Agnès Villers, Eve Peeraer, Arjan Buist, Dick Terwel, Peter Baatsen, Tutu Oyelami, Nathalie Pierrot, Cindy Casteels, Guy Bormans, Pascal Kienlen-Campard

and 3 other authors

Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice

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This paper is available in a repository.

Salim Hage

, Serena Stanga

, Claudia Marinangeli, Jean-Noël Octave, Ilse Dewachter, Joëlle Quetin-Leclercq, Pascal Kienlen-Campard

Characterization of Pterocarpus erinaceus kino extract and its gamma-secretase inhibitory properties

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Claudia Marinangeli, Bernadette Tasiaux, Rémi Opsomer, Salim Hage, Alejandro O. Sodero, Ilse Dewachter, Jean-Noël Octave, Steven O. Smith, Stefan N. Constantinescu, Pascal Kienlen-Campard

Presenilin Transmembrane Domain 8 conserved AxxxAxxxG Motifs Are Required for the Activity of the γ-Secretase Complex.

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Marie Decock, Laetitia El Haylani, Serena Stanga, Ilse Dewachter, Jean-Noël Octave, Steven O. Smith, Stefan N. Constantinescu, Pascal Kienlen-Campard

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing.

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Serena Stanga, Bidossessi Nadège Zanou

, Emilie Audouard, Bernadette Tasiaux, Sabrina Contino, Gaëlle Vandermeulen, Frédérique Rene, Jean-Philippe Loeffler, Frédéric Clotman, Philippe Gailly, Ilse Dewachter, Use Dewachter, Jean-Noël Octave, Pascal Kienlen-Campard

APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation.

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2014 Aurélie Hendrickx, Nathalie Pierrot, Bernadette Tasiaux, Olivier Schakman, Pascal Kienlen-Campard

, Charles De Smet, Jean-Noël Octave

Epigenetic Regulations of Immediate Early Genes Expression Involved in Memory Formation by the Amyloid Precursor Protein of Alzheimer Disease

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Ilie-Cosmin Stancu, Laurence Ris, Bruno Vasconcelos, Bruno Barbosa de Vasconcelos, Claudia Marinangeli, Léonie Goeminne, Vincent Laporte, Laetitia El Haylani, Laetitia E. Haylani, Julie Couturier, Olivier Schakman, Philippe Gailly, Nathalie Pierrot, Pascal Kienlen-Campard

, Jean-Noel Octave and 1 other authors

Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer’s disease

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Tzu-Chun Tang, Yi Hu, Pascal Kienlen-Campard

, Laetitia El Haylani, Laetitia El Haylani, Marie Decock, Joanne Van Hees, Ziao Fu, Jean-Noel Octave, Stefan N. Constantinescu, Steven O. Smith

Conformational Changes Induced by the A21G Flemish Mutation in the Amyloid Precursor Protein Lead to Increased Aβ Production

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2013 Aurélie Hendrickx, Nathalie Pierrot, Bernadette Tasiaux, Olivier Schakman, Jean-Pierre Brion, Pascal Kienlen Kienlen-Campard

, Charles De Smet, Jean-Noël Octave

Epigenetic Induction of EGR-1 Expression by the Amyloid Precursor Protein during Exposure to Novelty

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Nathalie Pierrot, Donatienne Tyteca, Ludovic D'auria, Ilse Dewachter, Philippe Gailly, Aurélie Hendrickx, Bernadette Tasiaux, Laetitia El Haylani, Laetitia El Haylani, Nathalie Muls, Francisca N'kuli, Annie Laquerrière, Jean-Baptiste Demoulin, Dominique Campion, Jean-Pierre Brion and 3 other authors

Amyloid precursor protein controls cholesterol turnover needed for neuronal activity.

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2012 Naouel Ben Khalifa, Donatienne Tyteca, Pierre J. Courtoy, Jean-Christophe Renauld

, Stefan N. Constantinescu, Jean-Noël Octave, Pascal Kienlen-Campard

Contribution of Kunitz protease inhibitor and transmembrane domains to amyloid precursor protein homodimerization

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2011 Naouel Ben Khalifa, Naouel Ben Khalifa, Donatienne Tyteca, Claudia Marinangeli, Mathieu Depuydt, Jean-François Collet, Pierre J. Courtoy, Jean-Christophe Renauld

, Stefan N. Constantinescu, Jean-Noël Octave, Pascal Kienlen-Campard

Structural features of the KPI domain control APP dimerization, trafficking, and processing

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2010 Salim Hage, Pascal Kienlen-Campard

, Jean-Noël Octave, Joëlle Quetin-Leclercq

In vitro screening on β-amyloid peptide production of plants used in traditional medicine for cognitive disorders

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All papers authored by Pascal Kienlen-Campard