Gabriella Guerrini

Papers authored by Gabriella Guerrini

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2015 Maria Paola Giovannoni, Igor A. Schepetkin, Letizia Crocetti, Giovanna Ciciani, Agostino Cilibrizzi

, Gabriella Guerrini

, Andrei I. Khlebnikov

, Mark T. Quinn, Claudia Vergelli

Cinnoline derivatives as human neutrophil elastase inhibitors

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Maria Paola Giovannoni, Giovanna Ciciani, Agostino Cilibrizzi

, Letizia Crocetti, Simona Daniele, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Chiara Giacomelli

, Gabriella Guerrini

, Claudia Martini

, Maria Letizia Trincavelli

, Claudia Vergelli

Further studies on pyrazolo[1′,5′:1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists

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2013 Gabriella Guerrini

, Giovanna Ciciani, Annarella Costanzo, Simona Daniele, Claudia Martini

, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Samuele Ciattini

Synthesis of novel cognition enhancers with pyrazolo[5,1- c ][1,2,4]benzotriazine core acting at γ-aminobutyric acid type A (GABA A ) receptor

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Gabriella Guerrini

, Giovanna Ciciani

Benzodiazepine receptor ligands: A patent review (2006-2012)

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2011 Gabriella Guerrini

, Giovanna Ciciani, Fabrizio Bruni, Silvia Selleri, Claudia Martini

, Simona Daniele, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Annarella Costanzo

Development of ligands at γ-aminobutyrric acid type A (GABAA) receptor subtype as new agents for pain relief

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Gabriella Guerrini

, Giovanna Ciciani, Fabrizio Bruni, Silvia Selleri, Fabrizio Melani, Simona Daniele, Claudia Martini

, Annarella Costanzo

New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the γ-aminobutyric acid type A (GABAA) receptor

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2010 Gabriella Guerrini

, Giovanna Ciciani, Fabrizio Bruni, Silvia Selleri, Chiara Guarino, Fabrizio Melani, Marina Montali, Simona Daniele, Claudia Martini

, Carla Ghelardini, Monica Norcini, Samuele Ciattini

, Annarella Costanzo

New Fluoro Derivatives of the Pyrazolo[5,1-c][1,2,4]benzotriazine 5-Oxide System: Evaluation of Fluorine Binding Properties in the Benzodiazepine Site on γ-Aminobutyrric Acid Type A (GABAA) Receptor. Design, Synthesis, Biological, and Molecular Modeling Investigation

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2009 Gabriella Guerrini

, Giovanna Ciciani, Giovanni Cambi, Fabrizio Bruni, Silvia Selleri, Chiara Guarino, Fabrizio Melani, Marina Montali, Claudia Martini

, Carla Ghelardini, Monica Norcini, Annarella Costanzo

Synthesis, in Vivo Evaluation, and Molecular Modeling Studies of New Pyrazolo[5,1-c][1,2,4]benzotriazine 5-Oxide Derivatives. Identification of a Bifunctional Hydrogen Bond Area Related to the Inverse Agonism

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2008 Giovanna Ciciani, Marcella Coronnello, Gabriella Guerrini

, Silvia Selleri, Miriam Cantore, Paola Failli, Enrico Mini, Annarella Costanzo

Synthesis of new pyrazolo[5,1-c][1,2,4] benzotriazines, pyrazolo[5,1-c]pyrido[4,3-e][1,2,4] triazines and their open analogues as cytotoxic agents in normoxic and hypoxic conditions

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Gabriella Guerrini

, Giovanna Ciciani, Giovanni Cambi, Fabrizio Bruni, Silvia Selleri, Fabrizio Melani, Marina Montali, Claudia Martini

, Carla Ghelardini, Monica Norcini, Annarella Costanzo

Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: Synthesis, pharmacological and molecular modeling studies

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Stefano Chimichi, Marco Boccalini, Silvia Selleri, Camilla Costagli, Gabriella Guerrini

, Giampietro Viola

On the reactivity of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidines with 1,3- and 1,4-bisnucleophiles

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2007 Gabriella Guerrini

, Giovanna Ciciani, Giovanni Cambi, Fabrizio Bruni, Silvia Selleri, François Besnard, Marina Montali, Claudia Martini

, Carla Ghelardini, Nicoletta Galeotti, Annarella Costanzo

Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of α5-inverse agonist useful tools for therapy of mnemonic damage

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2006 Gabriella Guerrini

, Annarella Costanzo, Giovanna Ciciani, Fabrizio Bruni, Silvia Selleri, Camilla Costagli, François Besnard, Barbara Costa, Claudia Martini

, Gaetano De Siena, Petra Malmberg-Aiello

Benzodiazepine receptor ligands. 8: Synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3-and 8-disubstituted: High affinity ligands endowed with inverse-agonist pharmacological efficacy

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2005 Silvia Selleri, Paola Gratteri, Camilla Costagli, Claudia Bonaccini, Annarella Costanzo, Fabrizio Melani, Gabriella Guerrini

, Giovanna Ciciani, Barbara Costa, Francesca Spinetti, Claudia Martini

, Fabrizio Bruni

Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: Synthesis, biological evaluation and 3D-QSAR investigation

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Marcella Coronnello, Giovanna Ciciani, Enrico Mini, Gabriella Guerrini

, Barbara Caciagli, Silvia Selleri, Annarella Costanzo, Teresita Mazzei

Cytotoxic activity of 3-nitropyrazolo[5,1-c][1,2,4]benzotriazine derivatives: a new series of anti-proliferative agents:

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2002 Silvia Selleri, Fabrizio Bruni, Camilla Costagli, Annarella Costanzo, Gabriella Guerrini

, Giovanna Ciciani, Paola Gratteri, Claudia Bonaccini, Petra Malmberg Aiello, François Besnard, Stephane Renard, Barbara Costa, Claudia Martini

Synthesis and Benzodiazepine Receptor Affinity of Pyrazolo[1,5-a]pyrimidine Derivatives. 3. New 6-(3-Thienyl) Series as α1 Selective Ligands

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Annarella Costanzo, Gabriella Guerrini

, Giovanna Ciciani, Fabrizio Bruni, Camilla Costagli, Silvia Selleri, François Besnard, Barbara Costa, Claudia Martini

, Petra Malmberg-Aiello

Benzodiazepine Receptor Ligands. 7. Synthesis and Pharmacological Evaluation of New 3-Esters of the 8-Chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide. 3-(2-Thienylmethoxycarbonyl) Derivative: An Anxioselective Agent in Rodents

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A. Costanzo, G. Guerrini

, G. Ciciani, F. Bruni, C. Costagli, S. Selleri, B. Costa, C. Martini

, P. Malmberg-Aiello

Synthesis and pharmacological evaluation of 3-(2-furyl)- and 3-(3-furyl)8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides, new 3-heteroaryl substituted Benzodiazepine Receptor ligands

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2001 Silvia Selleri, Fabrizio Bruni, Camilla Costagli, Annarella Costanzo, Gabriella Guerrini

, Giovanna Ciciani, Barbara Costa, Claudia Martini

2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands

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A. Costanzo, G. Guerrini

, G. Ciciani, F. Bruni, C. Costagli, S. Selleri, B. Costa, C. Martini

, P. Malmberg Aiello

Benzodiazepine receptor (BZR) ligands. 6 New 3-(2-, 3- or 4-substituted benzyloxycarbonyl) derivatives of the 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide: Receptor affinity and in vivo testing

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Papers authored by Gabriella Guerrini