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Functional regulatory variants implicate distinct transcriptional networks in dementia
UploadBRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2
Download from www.nature.comGenome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
Download from www.nature.comMolecular characterization of selectively vulnerable neurons in Alzheimer’s disease
Download from www.nature.comRobust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding
UploadCRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma
Download from ashpublications.orgDeep mutational scanning reveals the structural basis for α-synuclein activity
Download from www.nature.comMitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway
Download from www.nature.comHeterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity
UploadValidation of the Hsp70-Bag3 Protein-Protein Interaction as a Potential Therapeutic Target in Cancer
Download from mct.aacrjournals.orgGenome-Scale CRISPR-Mediated Control of Gene Repression and Activation
Download from www.ncbi.nlm.nih.govUnraveling the mechanism of cell death induced by chemical fibrils
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