Stuart Conway - Dissemin

All papers authored by Stuart Conway

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2017 Christos Pliotas, Samuel C. Grayer, Silvia Ekkerman, Anthony K. N. Chan, Jess Healy, Phedra Marius, Wendy Bartlett, Amjad Khan, Wilian A. Cortopassi, Shane A. Chandler, Tim Rasmussen

, Justin L. P. Benesch, Robert S. Paton

, Timothy D. W. Claridge

, Samantha Miller and 3 other authors

Adenosine Monophosphate Binding Stabilizes the KTN Domain of the Shewanella denitrificans Kef Potassium Efflux System

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This paper is available in a repository.

2016 Kyle C. Costa, Nathaniel R. Glasser, Stuart J. Conway

, Dianne K. Newman

Pyocyanin degradation by a tautomerizing demethylase inhibits Pseudomonas aeruginosa biofilms

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Michael Brand, Angelina R. Measures, Brian G. Wilson, Wilian A. Cortopassi, Rikki Alexander, Matthias Höss, David S. Hewings, Timothy P. C. Rooney, Robert S. Paton, Stuart J. Conway

Correction to Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions

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This paper is made freely available by the publisher.

Jess Healy, Tim Rasmussen

, Samantha Miller, Ian R. Booth, Stuart J. Conway

The photochemical thiol-ene reaction as a versatile method for the synthesis of glutathione S-conjugates targeting the bacterial potassium efflux system Kef

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2015 C.-H. Wu, L. Kong, M. Bialecka-Fornal, S. Park, A. L. Thompson, G. Kulkarni, S. J. Conway

, D. K. Newman

Quantitative hopanoid analysis enables robust pattern detection and comparison between laboratories

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Mark Gregory, Meng-Xin Yin, Malcolm J. McConville, Eleanor Williams, Alex N. Bullock, Stuart J. Conway

, Antony W. Burgess, Bruno Catimel, Andrew B. Holmes

Synthesis of Highly Water-Soluble Adamantyl Phosphoinositide Derivatives

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David S. Hewings, Timothy P. C. Rooney, Stuart J. Conway

Emerging Epigenetic Therapies—Bromodomain Ligands

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Liam J. O'Connor, Cindy Cazares-Körner, Jaideep Saha, Charles N. G. Evans, Michael R. L. Stratford, Ester M. Hammond, Stuart J. Conway

Efficient synthesis of 2-nitroimidazole derivatives and the bioreductive clinical candidate Evofosfamide (TH-302)

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2014 Michael Brand, Angelina M. Measures, Brian G. Wilson, Wilian A. Cortopassi, Rikki Alexander, Matthias Höss, David S. Hewings, Timothy P. C. Rooney, Robert S. Paton, Stuart J. Conway

Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions

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Sj Conway

, Pm Woster, William J. Greenlee, Jing-Kang Shen, Gunda Georg, Shaomeng Wang

Epigenetics: Novel Therapeutics Targeting Epigenetics.

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Duncan A. Hay, Oleg Fedorov, Sarah Martin, Dean C. Singleton, Cynthia Tallant, Christopher Wells, Sarah Picaud, Martin Philpott, Octovia P. Monteiro, Catherine M. Rogers, Stuart J. Conway

, Timothy P. C. Rooney, Anthony Tumber, Clarence Yapp, Panagis Filippakopoulos and 5 other authors

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

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Tp Rooney, Panagis Filippakopoulos, Oleg Fedorov, Sarah Picaud, Wa Cortopassi, Da Hay, Sarah Martin, Anthony Tumber, Cm Rogers, Martin Philpott, Minghua Wang, Al Thompson, Td Heightman, Dc Pryde, Andrew Cook and 5 other authors

A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction.

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Jessica Healy, Silvia Ekkerman, Christos Pliotas

, Morgiane Richard, Wendy Bartlett, Samuel C. Grayer, Garrett M. Morris, Samantha Miller, Ian Rylance Booth, Stuart J. Conway

, Tim Rasmussen

Understanding the Structural Requirements for Activators of the Kef Bacterial Potassium Efflux System

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Laura E. Jennings, Angelina R. Measures, Brian G. Wilson, Stuart J. Conway

Phenotypic screening and fragment-based approaches to the discovery of small-molecule bromodomain ligands

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2013 Cindy Cazares-Körner, Isabel M. Pires, Id Diane Swallow, I. Diane Swallow, Samuel C. Grayer, Liam J. O'Connor, Liam J. O’Connor, Monica Mm Olcina, Martin Christlieb, Stuart J. Conway

, Ester M. Hammond

CH-01 is a Hypoxia-Activated Prodrug That Sensitizes Cells to Hypoxia/Reoxygenation Through Inhibition of Chk1 and Aurora A

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David S. Hewings, Oleg Fedorov, Panagis Filippakopoulos, Sarah Martin, Sarah Picaud, Anthony Tumber, Christopher Wells, Monica M. Olcina, Katherine Freeman, Andrew Gill, Alison J. Ritchie, David W. Sheppard, Angela J. Russell, Ester M. Hammond, Stefan Knapp and 2 other authors

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

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Duncan Hay, Oleg Fedorov, Panagis Filippakopoulos, Sarah Martin, Martin Philpott, Sarah Picaud, Ds Hewings, Sagar Uttakar, Td Heightman, Sj Conway

, Stefan Knapp, Pe Brennan

The design and synthesis of 5-and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains

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2012 Lc Davis, Aj Morgan, Jl Chen, Cm Snead, Duncan Bloor-Young, Eugene Shenderov, Mn Stanton-Humphreys, Sj Conway

, Gc Churchill, John Parrington, Vincenzo Cerundolo, Antony Galione

NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing.

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Ds Hewings, Tp Rooney, Le Jennings, Da Hay, Cj Schofield, Pe Brennan, Stefan Knapp, Sj Conway

Progress in the development and application of small molecule inhibitors of bromodomain-acetyl-lysine interactions.

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Stuart J. Conway

Bromodomains: Are Readers Right for Epigenetic Therapy?

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All papers authored by Stuart Conway