Christopher Lord - Dissemin

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Papers authored by Christopher Lord

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2013 S. Postel Vinay, I. Bajrami, L. Friboulet

ORCID

, R. Elliott, Y. Fontebasso, N. Dorvault, K. A. Olaussen, F. André

ORCID

, J.-C. Soria, C. J. Lord

ORCID

, A. Ashworth

A high-throughput screen identifies PARP1/2 inhibitors as a potential therapy for ERCC1-deficient non-small cell lung cancer

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Joo Ern Ang, Charlie Gourley, C. Bethan Powell, Hilda High, Ronnie Shapira-Frommer, Vincent Castonguay, Jacques De Greve, Tina Atkinson, Timothy A. Yap, Shahneen Sandhu

ORCID

, Susana Banerjee

ORCID

, Lee-May Chen, Michael L. Friedlander, Bella Kaufman, Amit M. Oza and 12 other authors

Efficacy of Chemotherapy in BRCA1/2 Mutation Carrier Ovarian Cancer in the Setting of PARP Inhibitor Resistance: A Multi-Institutional Study

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Todd R. Mereniuk, Mohamed A. M. El Gendy, El Gendy, Ana M. Mendes-Pereira, Christopher J. Lord

ORCID

, Sunita Ghosh, Edan Foley, Alan Ashworth, Michael Weinfeld

Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase

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This paper is made freely available by the publisher.

Yuqiao Shen, Farah L. Rehman, Ying Feng, Julia Boshuizen

ORCID

, Ilirjana Bajrami, Richard Elliott, Bing Wang, Christopher J. Lord

ORCID

, Leonard E. Post, Alan Ashworth

BMN 673, a Novel and Highly Potent PARP1/2 Inhibitor for the Treatment of Human Cancers with DNA Repair Deficiency

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Sari Neijenhuis, Ilirjana Bajrami, Rowan Miller, Christopher J. Lord

ORCID

, Alan Ashworth

Identification of miRNA modulators to PARP inhibitor response

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Yari Fontebasso, Christopher J. Lord

ORCID

, Alan Ashworth

Abstract A09: Induced aggravation of oxidative DNA damage as a targeted synthetic lethal approach in mismatch repair-deficient tumors

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Tim Fenton, Rachel Brough, Luke Williams, Ilirjana Bajrami, Alan Ashworth, Chris Lord

ORCID

, Chris Boshoff

Abstract B28: Screening for kinase dependencies in HPV-associated cancer

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Stephen J. Pettitt, Farah L. Rehman, Ilirjana Bajrami, Helen Pemberton, Rachel Brough, Iwanka Kozarewa, Christopher J. Lord

ORCID

, Alan Ashworth

Abstract A36: A transposon-based genetic screen in haploid mouse embryonic stem cells identifies Parp1 as a major mediator of olaparib toxicity

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Stephen J. Pettitt, Farah L. Rehman, Ilirjana Bajrami, Rachel Brough, Fredrik Wallberg, Iwanka Kozarewa, Kerry Fenwick, Ioannis Assiotis, Lina Chen, James Campbell, Christopher J. Lord

ORCID

, Alan Ashworth

A Genetic Screen Using the PiggyBac Transposon in Haploid Cells Identifies Parp1 as a Mediator of Olaparib Toxicity

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Lynn Bjerke, Bjerke,Lynn, Alan Mackay, Meera Nandhabalan, Anna Burford, Alexa Jury, Sergey Popov, Dorine A. Bax, Diana Carvalho, Kathryn R. Taylor, Maria Vinci

ORCID

, Ilirjana Bajrami, Imelda M. McGonnell, Christopher J. Lord

ORCID

, Rui M. Reis and 4 other authors

Histone H3.3 mutations drive pediatric glioblastoma through upregulation of MYCN

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S. K. Sandhu

ORCID

, A. Omlin, L. Hylands, S. Miranda, L. J. Barber, R. Riisnaes, A. H. Reid, G. Attard, L. Chen, I. Kozarewa, H. Gevensleben, J. Campbell, K. Fenwick, I. Assiotis, D. Olmos and 9 other authors

Poly (ADP-ribose) polymerase (PARP) inhibitors for the treatment of advanced germline BRCA2 mutant prostate cancer

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D. Wetterskog, K.-K. Shiu, I. Chong, T. Meijer, A. Mackay, M. Lambros, D. Cunningham

ORCID

, J. S. Reis-Filho, C. J. Lord

ORCID

, A. Ashworth

Identification of novel determinants of resistance to lapatinib in ERBB2-amplified cancers

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Christopher Lord

ORCID

, Susan Ferro-Novick, Elizabeth A. Miller

ORCID

The Highly Conserved COPII Coat Complex Sorts Cargo from the Endoplasmic Reticulum and Targets It to the Golgi

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Neil Rajan, John Burn, James Langtry, Maya Sieber-Blum, Chris Lord

ORCID

, Alan Ashworth

Loss of organisation in CYLD defective tumours is associated with diminished DKK2 expression.

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M. Hewish, S. A. Martin, R. Elliott, D. Cunningham

ORCID

, C. J. Lord

ORCID

, A. Ashworth

Cytosine-based nucleoside analogs are selectively lethal to DNA mismatch repair-deficient tumour cells by enhancing levels of intracellular oxidative stress

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K.-K. Shiu, D. Wetterskog, A. Mackay, R. Natrajan, M. Lambros, D. Sims, I. Bajrami, R. Brough, J. Frankum, R. Sharpe, C. Marchio, H. Horlings, M. van der Vijver, F. Reyal, M. V. Der and 4 other authors

Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies.

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Sophie C. Postel-Vinay, Ilirjana Bajrami, Luc Friboulet, Marieke Aarts, Yari Fontebasso, Fabrice Andre, Ken Olaussen, Jean-Charles Soria, Chris Lord

ORCID

, Alan Ashworth

High-throughput screens identify PARP inhibition as being synthetically lethal with ERCC1 deficiency in non-small cell lung cancer cell lines.

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Cky Ng, A. Gauthier, Pm Wilkerson, Mb Lambros, L. Arnoud, M. Lacroix-Triki, F. Penault-Llorca, Mc Baranzelli, X. Sastre-Garau, Cj Lord

ORCID

Characterisation of the Genetic Heterogeneity of Invasive Breast Cancers with Heterogeneous HER2 Overexpression and Gene Amplification

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Diana Carvalho, Alan Mackay, Anna Burford, Lynn Bjerke, Lina Chen, Iwanka Kozarewa, Chris Lord

ORCID

, Alan Ashworth, Darren Hargrave

ORCID

, Rui Reis, Chris Jones

Integrated Whole Genome and Rna Sequencing Identifies Novel Expressed Fusion Transcripts in Paediatric High Grade Glioma

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2012 Elise Ruark, Katie Snape, Peter Humburg, Chey Loveday, Ilirjana Bajrami, Daniel Nava Rodrigues, Rachel Brough, Silvana Del Vecchio Duarte, Anthony Renwick, Rivas Ma, Silvana Del Vecchio Duarte, Sheila Seal, Rodrigues Dn, Manuel A. Rivas, Emma Ramsay and 68 other authors

Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer.

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