Irena Loryan - Dissemin

All papers authored by Irena Loryan

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2022 Irena Loryan

, Andreas Reichel, Bo Feng, Christoffer Bundgaard

, Christopher Shaffer, Cory Kalvass, Dallas Bednarczyk, Denise Morrison, Dominique Lesuisse, Edmund Hoppe, Georg C. Terstappen, Holger Fischer, Li Di, Nicola Colclough, Scott Summerfield and 3 other authors

Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain—a Game Changing Parameter for CNS Drug Discovery and Development

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2019 Elena Puris

, Mikko Gynther

, Elizabeth C. M. de Lange

, Seppo Auriola, Margareta Hammarlund-Udenaes, Kristiina M. Huttunen

, Irena Loryan

Mechanistic Study on the Use of the l-Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the Development of Prodrugs for Intracellular Targets

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2018 Siti R. Yusof

, Mahathir Mohd Uzid, Eng-Huat Teh, Nur Aziah Hanapi, Mazlin Mohideen, Ahmad Saifuddin Mohamad Arshad, Mohd Nizam Mordi, Irena Loryan

, Margareta Hammarlund-Udenaes

Rate and extent of mitragynine and 7-hydroxymitragynine blood-brain barrier transport and their intra-brain distribution: the missing link in pharmacodynamic studies

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2014 Achiel van Peer, Vikash Sinha, Irena Loryan

, Claire Mackie, Wilhelmus H. Drinkenburg, An Vermeulen, Donald Heald, Carola M. Wassvik, Margareta Hammarlund-Udenaes

Molecular Properties Determining Unbound Intracellular and Extracellular Brain Exposure of CNS Drug Candidates

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Xiaomei Chen, Maryam Payan, David E. Smith, Richard F. Keep, Irena Loryan

, Margareta Hammarlund-Udenaes

Effect of transporter inhibition on the distribution of cefadroxil in rat brain

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Irena Loryan

, Vikash Sinha, Claire Mackie, Achiel Van Peer, Wilhelmus Drinkenburg, An Vermeulen, Denise Morrison, Mario Monshouwer, Donald Heald, Margareta Hammarlund-Udenaes

Mechanistic understanding of brain drug disposition to optimize the selection of potential neurotherapeutics in drug discovery

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2013 Irena Loryan

, Margareta Hammarlund-Udenaes

Drug Discovery Methods for Studying Brain Drug Delivery and Distribution

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Eva Choong, Iren Loryan

, Marja Lindqvist, Asa Nordling, Samira Elbouazzaoui, Samira el Bouazzaoui, Ron H. van Schaik, Inger Johansson, Jan Jakobsson, Magnus Ingelman-Sundberg

Sex Difference in Formation of Propofol Metabolites: A Replication Study

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Irena Loryan

, Markus Fridén, Margareta Hammarlund-Udenaes

The brain slice method for studying drug distribution in the CNS

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2012 T. Haslemo, I. Loryan

, N. Ueda, B. Mannheimer, L. Bertilsson, M. Ingelman Sundberg, E. Molden, E. Eliasson

UGT1A4*3 Encodes Significantly Increased Glucuronidation of Olanzapine in Patients on Maintenance Treatment and in Recombinant Systems

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2011 Irena Loryan

, Marja Lindqvist, Inger Johansson, Masahiro Hiratsuka, Ilse van der Heiden, Ron Hn N. van Schaik, Jan Jakobsson, Magnus Ingelman-Sundberg

Influence of sex on propofol metabolism, a pilot study: Implications for propofol anesthesia

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All papers authored by Irena Loryan