Scott Armstrong
Dana Farber Cancer Institute
16 papers found
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Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery
Download from doi.orgEpitope editing enables targeted immunotherapy of acute myeloid leukaemia
UploadKDM6A epigenetically regulates subtype plasticity in small cell lung cancer
UploadMLL3 regulates the CDKN2A tumor suppressor locus in liver cancer
Download from doi.orgMEN1 mutations mediate clinical resistance to menin inhibition
UploadThe menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia
Download from www.nature.comMutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia
Download from aacrjournals.orgA Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin–MLL Inhibition
UploadYBX1 mediates translation of oncogenic transcripts to control cell competition in AML
Download from www.nature.comHigh-resolution characterization of gene function using single-cell CRISPR tiling screen
Download from www.nature.comTherapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia
UploadA dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies
UploadTargeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma
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