Michael Hay - Dissemin

Papers authored by Michael Hay

This paper is made freely available by the publisher.

2013 Satish K. Chitneni, Gerald T. Bida, Hong Yuan, Gregory M. Palmer, Michael P. Hay

, Thorsten Melcher, William R. Wilson, Michael R. Zalutsky, Mark W. Dewhirst

18F-EF5 PET Imaging as an Early Response Biomarker for the Hypoxia-Activated Prodrug SN30000 Combined with Radiation Treatment in a Non–Small Cell Lung Cancer Xenograft Model

Download from jnm.snmjournals.org

Laura K. Green, Sophie P. Syddall, Kendall M. Carlin, Glenn D. Bell, Christopher P. Guise, Alexandra M. Mowday, Michael P. Hay

, Jeffrey B. Smaill, Adam V. Patterson, David F. Ackerley

Pseudomonas aeruginosa NfsB and nitro-CBI-DEI – a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy

Download from link.springer.com

This paper is available in a repository.

Muriel Bonnet, Jack U. Flanagan, Denise A. Chan, Amato J. Giaccia, Michael P. Hay

Identifying novel targets in renal cell carcinoma: Design and synthesis of affinity chromatography reagents

Download from europepmc.org

2012 Michelle A. Hunt, Dan Li, Michael P. Hay

, Mj Currie, Bridget A. Robinson, Av Patterson, Gu Dachs

Characterisation of enzyme prodrug gene therapy combinations in coated spheroids and vascular networks in vitro

Download from www.researchgate.net

Fw Hunter, Jingli Wang, Rita Patel, Huai-Ling Hsu, Aj Hickey, Michael P. Hay

, Wr Wilson

Homologous recombination repair-dependent cytotoxicity of the benzotriazine di-N-oxide CEN-209: Comparison with other hypoxia-activated prodrugs

Download from www.researchgate.net

2011 Jingli Wang, Annika Foehrenbacher, Jiechuang Su, Rita Patel, Michael P. Hay

, Kevin O. Hicks, Wr R. Wilson

The 2-nitroimidazole EF5 is a biomarker for oxidoreductases that activate the bioreductive prodrug CEN-209 under hypoxia.

Download from aacrjournals.org

Denise A. Chan, Patrick D. Sutphin, Phuong Nguyen, Sandra Turcotte, Edwin W. Lai, Alice Banh, Gloria E. Reynolds, Jen-Tsan Chi

, Jason Wu, David E. Solow-Cordero, Muriel Bonnet, Jack U. Flanagan, Donna M. Bouley, Edward Ee Graves, William A. Denny and 2 other authors

Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality

Download from www.ncbi.nlm.nih.gov

Muriel Bonnet, Jack U. Flanagan, Denise A. Chan, Edwin W. Lai, Phuong Nguyen, Amato J. Giaccia, Michael P. Hay

SAR Studies of 4-Pyridyl Heterocyclic Anilines that Selectively Induce Autophagic Cell Death in von Hippel-Lindau-Deficient Renal Cell Carcinoma Cells

Download from www.ncbi.nlm.nih.gov

Wr Wilson, Michael P. Hay

Targeting hypoxia in cancer therapy

Download from www.nature.com

2010 Sujata Ss Shinde, Andrej Maroz, Michael P. Hay

, Av Patterson, Wa Denny, Rf Anderson

Characterization of radicals formed following enzymatic reduction of 3-substituted analogues of the hypoxia-selective cytotoxin 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine)

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Ko O. Hicks, Bg G. Siim, Jk K. Jaiswal, Fb B. Pruijn, Am M. Fraser, Rita Patel, Alison Hogg, Hds D. Sarath Liyanage, H. D. Sarath Liyanage, Mj J. Dorie, Jm Martin Brown, J. Martin Brown, Wa A. Denny, Michael P. Hay

, Wr R. Wilson

Pharmacokinetic/Pharmacodynamic Modeling Identifies SN30000 and SN29751 as Tirapazamine Analogues with Improved Tissue Penetration and Hypoxic Cell Killing in Tumors

Download from aacrjournals.org

Michael P. Hay

, Sandra Turcotte, Ju Flanagan, Muriel Bonnet, Da Chan, Pd Sutphin, Phuong Nguyen, Aj Giaccia, Wa Denny

4-Pyridylanilinothiazoles that selectively target von Hippel-Lindau deficient renal cell carcinoma cells by inducing autophagic cell death

Download from www.ncbi.nlm.nih.gov

2009 Sujata Ss Shinde, Andrej Maroz, Michael P. Hay

, Robert F. Anderson

One-Electron Reduction Potential of the Neutral Guanyl Radical in the GC Base Pair of Duplex DNA

Download from www.ncbi.nlm.nih.gov

2008 Michael P. Hay

, Kevin O. Hicks, Karin Pchalek, Ho H. Lee, Adrian Blaser, Frederik B. Pruijn, Robert F. Anderson, Sujata S. Shinde, William R. Wilson, William A. Denny

Tricyclic [1,2,4]Triazine 1,4-Dioxides As Hypoxia Selective Cytotoxins

Download from www.ncbi.nlm.nih.gov

Sandra Turcotte, Denise A. Chan, Patrick Da Sutphin, Michael P. Hay

, William A. Denny, Amato J. Giaccia

A molecule targeting VHL-deficient Renal Cell Carcinoma that induces autophagy

Download from www.ncbi.nlm.nih.gov

Frederik B. Pruijn, Wilson Wr, Kashyap Patel, Michael P. Hay

, William R. Wilson, Kevin O. Hicks, Hicks Ko

Prediction of tumour tissue diffusion coefficients of hypoxia-activated prodrugs from physicochemical parameters

Download from www.publish.csiro.au

2007 Michael P. Hay

, Ko Hicks, Fb Pruijn, Karin Pchalek, Bg Siim, Wr Wilson, Wa Denny

Pharmacokinetic/pharmacodynamic model-guided identification of hypoxia-selective 1,2,4-benzotriazine 1,4-dioxides with antitumor activity: The role of extravascular transport

Download from www.researchgate.net

Michael P. Hay

, Karin Pchalek, Fb Pruijn, Ko Hicks, Bg Siim, Rf Anderson, Sujata Ss Shinde, Victoria Phillips, Wa Denny, Wr Wilson

Hypoxia-selective 3-alkyl 1,2,4-benzotriazine 1,4-dioxides: The influence of hydrogen bond donors on extravascular transport and antitumor activity

Download from www.researchgate.net

2006 Karin Pchalek, Michael P. Hay

Stille Coupling Reactions in the Synthesis of Hypoxia-Selective 3-Alkyl-1,2,4-Benzotriazine 1,4-Dioxide Anticancer Agents

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Mg Billett, N. Guy Billett, Ag T. Phillis, L. Main, Bk K. Nicholson, Wa A. Denny, Hay

The 3-N-phenyl amide of all-cis-cyclopentane-1,2,3,4-tetracarboxylic acid as a potential pH-sensitive amine-releasing prodrug; intervention of imide formation around neutral pH.

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Papers authored by Michael Hay