Researcher
Dhirendra Simanshu
Frederick National Laboratory for Cancer Research
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9 papers found
All papers authored by Dhirendra Simanshu
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2023
Moon Hee Yang 
,
Timothy H. Tran ,
Bethany Hunt ,
Rebecca Agnor ,
Christian W. Johnson ,
Bing Shui ,
Timothy J. Waybright ,
Jonathan A. Nowak ,
Andrew G. Stephen ,
Dhirendra K. Simanshu ,
Kevin M. Haigis
,
Timothy H. Tran ,
Bethany Hunt ,
Rebecca Agnor ,
Christian W. Johnson ,
Bing Shui ,
Timothy J. Waybright ,
Jonathan A. Nowak ,
Andrew G. Stephen ,
Dhirendra K. Simanshu ,
Kevin M. Haigis
Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity
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Fa-An Chao,
Albert H. Chan,
Srisathiyanarayanan Dharmaiah ,
Charles D. Schwieters ,
Timothy H. Tran,
Troy Taylor,
Nitya Ramakrishnan,
Dominic Esposito ,
Dwight V. Nissley ,
Frank McCormick ,
Dhirendra K. Simanshu ,
Gabriel Cornilescu
,
Charles D. Schwieters ,
Timothy H. Tran,
Troy Taylor,
Nitya Ramakrishnan,
Dominic Esposito ,
Dwight V. Nissley ,
Frank McCormick ,
Dhirendra K. Simanshu ,
Gabriel Cornilescu
Reduced dynamic complexity allows structure elucidation of an excited state of KRASG13D
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2022
Helgi I. Ingólfsson,
Chris Neale,
Timothy S. Carpenter ,
Rebika Shrestha,
Cesar A. López ,
Timothy H. Tran ,
Tomas Oppelstrup,
Harsh Bhatia,
Liam G. Stanton,
Xiaohua Zhang,
Shiv Sundram,
Francesco Di Natale,
Animesh Agarwal,
Gautham Dharuman,
Sara I. L. Kokkila Schumacher
and 27 other authors
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,
Rebika Shrestha,
Cesar A. López ,
Timothy H. Tran ,
Tomas Oppelstrup,
Harsh Bhatia,
Liam G. Stanton,
Xiaohua Zhang,
Shiv Sundram,
Francesco Di Natale,
Animesh Agarwal,
Gautham Dharuman,
Sara I. L. Kokkila Schumacher
and 27 other authors
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2021
Pau Castel ,
Srisathiyanarayanan Dharmaiah,
Matthew J. Sale,
Simon Messing ,
Gabrielle Rizzuto ,
Antonio Cuevas-Navarro ,
Alice Cheng,
Michael J. Trnka ,
Anatoly Urisman ,
Dominic Esposito ,
Dhirendra K. Simanshu ,
Frank McCormick
,
Srisathiyanarayanan Dharmaiah,
Matthew J. Sale,
Simon Messing ,
Gabrielle Rizzuto ,
Antonio Cuevas-Navarro ,
Alice Cheng,
Michael J. Trnka ,
Anatoly Urisman ,
Dominic Esposito ,
Dhirendra K. Simanshu ,
Frank McCormick
RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity
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Timothy H. Tran,
Albert H. Chan,
Lucy C. Young,
Lakshman Bindu,
Chris Neale,
Simon Messing,
Srisathiyanarayanan Dharmaiah ,
Troy Taylor,
John-Paul Denson,
Dominic Esposito ,
Dwight V. Nissley ,
Andrew G. Stephen,
Frank McCormick ,
Dhirendra K. Simanshu
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,
Troy Taylor,
John-Paul Denson,
Dominic Esposito ,
Dwight V. Nissley ,
Andrew G. Stephen,
Frank McCormick ,
Dhirendra K. Simanshu
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2020
Que N. Van ,
Cesar A. López ,
Marco Tonelli ,
Troy Taylor ,
Ben Niu ,
Christopher B. Stanley ,
Debsindhu Bhowmik ,
Timothy H. Tran ,
Peter H. Frank ,
Simon Messing ,
Patrick Alexander ,
Daniel Scott ,
Xiaoying Ye ,
Matt Drew ,
Oleg Chertov
and 14 other authors
,
Cesar A. López ,
Marco Tonelli ,
Troy Taylor ,
Ben Niu ,
Christopher B. Stanley ,
Debsindhu Bhowmik ,
Timothy H. Tran ,
Peter H. Frank ,
Simon Messing ,
Patrick Alexander ,
Daniel Scott ,
Xiaoying Ye ,
Matt Drew ,
Oleg Chertov
and 14 other authors
Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane
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Wupeng Yan ,
Evan Markegard,
Srisathiyanarayanan Dharmaiah ,
Anatoly Urisman ,
Matthew Drew ,
Dominic Esposito ,
Klaus Scheffzek,
Dwight V. Nissley ,
Frank McCormick,
Dhirendra K. Simanshu
Download from doi.org
,
Evan Markegard,
Srisathiyanarayanan Dharmaiah ,
Anatoly Urisman ,
Matthew Drew ,
Dominic Esposito ,
Klaus Scheffzek,
Dwight V. Nissley ,
Frank McCormick,
Dhirendra K. Simanshu
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2019
G. Aaron Hobbs ,
Anne M. Miermont,
Ryan D. Thurman,
Mariaelena Pierobon,
Timothy H. Tran,
Andrew M. Waters ,
J. Nathaniel Diehl ,
Bjoern Papke ,
Richard G. Hodge ,
Jennifer E. Klomp ,
Craig M. Goodwin,
Jonathan M. DeLiberty,
Junning Wang,
Raymond W. S. Ng ,
Prson Gautam
and 13 other authors
,
Anne M. Miermont,
Ryan D. Thurman,
Mariaelena Pierobon,
Timothy H. Tran,
Andrew M. Waters ,
J. Nathaniel Diehl ,
Bjoern Papke ,
Richard G. Hodge ,
Jennifer E. Klomp ,
Craig M. Goodwin,
Jonathan M. DeLiberty,
Junning Wang,
Raymond W. S. Ng ,
Prson Gautam
and 13 other authors
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
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