All papers authored by Timo Otonkoski
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2024
Väinö Lithovius 
,
Salla Lahdenpohja ,
Hazem Ibrahim ,
Jonna Saarimäki-Vire ,
Lotta Uusitalo,
Hossam Montaser ,
Kirsi Mikkola ,
Cheng-Bin Yim,
Thomas Keller,
Johan Rajander ,
Diego Balboa ,
Tom Barsby ,
Olof Solin,
Pirjo Nuutila ,
Tove J. Grönroos
and 1 other authors
,
Salla Lahdenpohja ,
Hazem Ibrahim ,
Jonna Saarimäki-Vire ,
Lotta Uusitalo,
Hossam Montaser ,
Kirsi Mikkola ,
Cheng-Bin Yim,
Thomas Keller,
Johan Rajander ,
Diego Balboa ,
Tom Barsby ,
Olof Solin,
Pirjo Nuutila ,
Tove J. Grönroos
and 1 other authors
Non-invasive quantification of stem cell-derived islet graft size and composition
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Kristiina Pulli,
Jonna Saarimäki-Vire ,
Pekka Ahonen,
Xiaonan Liu,
Hazem Ibrahim ,
Vikash Chandra,
Alice Santambrogio,
Yafei Wang ,
Kirsi Vaaralahti,
Anna-Pauliina Iivonen,
Johanna Känsäkoski,
Johanna Tommiska,
Yasmine Kemkem,
Markku Varjosalo,
Sanna Vuoristo
and 3 other authors
Download from doi.org
,
Pekka Ahonen,
Xiaonan Liu,
Hazem Ibrahim ,
Vikash Chandra,
Alice Santambrogio,
Yafei Wang ,
Kirsi Vaaralahti,
Anna-Pauliina Iivonen,
Johanna Känsäkoski,
Johanna Tommiska,
Yasmine Kemkem,
Markku Varjosalo,
Sanna Vuoristo
and 3 other authors
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Hazem Ibrahim ,
Diego Balboa ,
Jonna Saarimäki-Vire ,
Hossam Montaser ,
Oleg Dyachok ,
Per-Eric Lund ,
Muhmmad Omar-Hmeadi ,
Jouni Kvist ,
Om P. Dwivedi ,
Väinö Lithovius ,
Tom Barsby ,
Vikash Chandra ,
Solja Eurola ,
Jarkko Ustinov,
Tiinamaija Tuomi
and 4 other authors
,
Diego Balboa ,
Jonna Saarimäki-Vire ,
Hossam Montaser ,
Oleg Dyachok ,
Per-Eric Lund ,
Muhmmad Omar-Hmeadi ,
Jouni Kvist ,
Om P. Dwivedi ,
Väinö Lithovius ,
Tom Barsby ,
Vikash Chandra ,
Solja Eurola ,
Jarkko Ustinov,
Tiinamaija Tuomi
and 4 other authors
RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function
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2022
Tom Barsby ,
Hazem Ibrahim ,
Väinö Lithovius,
Hossam Montaser,
Diego Balboa,
Eliisa Vähäkangas,
Vikash Chandra,
Jonna Saarimäki-Vire,
Timo Otonkoski
,
Hazem Ibrahim ,
Väinö Lithovius,
Hossam Montaser,
Diego Balboa,
Eliisa Vähäkangas,
Vikash Chandra,
Jonna Saarimäki-Vire,
Timo Otonkoski
Differentiating functional human islet-like aggregates from pluripotent stem cells
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Vikash Chandra ,
Hazem Ibrahim ,
Clémentine Halliez ,
Rashmi B. Prasad ,
Federica Vecchio,
Om Prakash Dwivedi ,
Jouni Kvist ,
Diego Balboa ,
Jonna Saarimäki-Vire ,
Hossam Montaser,
Tom Barsby,
Väinö Lithovius,
Isabella Artner ,
Swetha Gopalakrishnan,
Leif Groop
and 3 other authors
,
Hazem Ibrahim ,
Clémentine Halliez ,
Rashmi B. Prasad ,
Federica Vecchio,
Om Prakash Dwivedi ,
Jouni Kvist ,
Diego Balboa ,
Jonna Saarimäki-Vire ,
Hossam Montaser,
Tom Barsby,
Väinö Lithovius,
Isabella Artner ,
Swetha Gopalakrishnan,
Leif Groop
and 3 other authors
The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α
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Diego Balboa ,
Tom Barsby,
Väinö Lithovius ,
Jonna Saarimäki-Vire ,
Muhmmad Omar-Hmeadi ,
Oleg Dyachok,
Hossam Montaser,
Per-Eric Lund,
Mingyu Yang ,
Hazem Ibrahim ,
Anna Näätänen,
Vikash Chandra ,
Helena Vihinen ,
Eija Jokitalo ,
Jouni Kvist
and 10 other authors
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,
Tom Barsby,
Väinö Lithovius ,
Jonna Saarimäki-Vire ,
Muhmmad Omar-Hmeadi ,
Oleg Dyachok,
Hossam Montaser,
Per-Eric Lund,
Mingyu Yang ,
Hazem Ibrahim ,
Anna Näätänen,
Vikash Chandra ,
Helena Vihinen ,
Eija Jokitalo ,
Jouni Kvist
and 10 other authors
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Julia Döhla,
Emilia Kuuluvainen,
Nadja Gebert,
Ana Amaral,
Johanna I. Englund ,
Swetha Gopalakrishnan,
Svetlana Konovalova,
Anni I. Nieminen,
Ella S. Salminen,
Rubén Torregrosa Muñumer,
Kati Ahlqvist,
Yang Yang,
Hien Bui,
Timo Otonkoski ,
Reijo Käkelä
and 4 other authors
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Swetha Gopalakrishnan,
Svetlana Konovalova,
Anni I. Nieminen,
Ella S. Salminen,
Rubén Torregrosa Muñumer,
Kati Ahlqvist,
Yang Yang,
Hien Bui,
Timo Otonkoski ,
Reijo Käkelä
and 4 other authors
Metabolic determination of cell fate through selective inheritance of mitochondria
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Bernat Elvira,
Valerie Vandenbempt,
Julia Bauzá-Martinez ,
Raphaël Crutzen,
Javier Negueruela,
Hazem Ibrahim ,
Matthew L. Winder,
Manoja K. Brahma,
Beata Vekeriotaite,
Pieter-Jan Martens,
Sumeet Pal Singh,
Fernando Rossello,
Pascale Lybaert,
Timo Otonkoski ,
Conny Gysemans
and 2 other authors
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,
Raphaël Crutzen,
Javier Negueruela,
Hazem Ibrahim ,
Matthew L. Winder,
Manoja K. Brahma,
Beata Vekeriotaite,
Pieter-Jan Martens,
Sumeet Pal Singh,
Fernando Rossello,
Pascale Lybaert,
Timo Otonkoski ,
Conny Gysemans
and 2 other authors
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2021
Hossam Montaser,
Kashyap A. Patel ,
Diego Balboa,
Hazem Ibrahim ,
Väinö Lithovius,
Anna Näätänen,
Vikash Chandra,
Korcan Demir,
Sezer Acar,
Tawfeg Ben-Omran,
Kevin Colclough,
Jonathan M. Locke ,
Matthew Wakeling,
Maria Lindahl ,
Andrew T. Hattersley
and 2 other authors
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Diego Balboa,
Hazem Ibrahim ,
Väinö Lithovius,
Anna Näätänen,
Vikash Chandra,
Korcan Demir,
Sezer Acar,
Tawfeg Ben-Omran,
Kevin Colclough,
Jonathan M. Locke ,
Matthew Wakeling,
Maria Lindahl ,
Andrew T. Hattersley
and 2 other authors
Loss of MANF causes childhood onset syndromic diabetes due to increased endoplasmic reticulum stress
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Lithovius V.,
Barsby T.,
Otonkoski T.,
Väinö Lithovius ,
Jonna Saarimäki-Vire ,
Saarimaki-Vire J.,
Diego Balboa ,
Balboa D.,
Hazem Ibrahim ,
Ibrahim H.,
Montaser H.,
Hossam Montaser,
Tom Barsby,
Timo Otonkoski
,
Jonna Saarimäki-Vire ,
Saarimaki-Vire J.,
Diego Balboa ,
Balboa D.,
Hazem Ibrahim ,
Ibrahim H.,
Montaser H.,
Hossam Montaser,
Tom Barsby,
Timo Otonkoski
SUR1-mutant iPS cell-derived islets recapitulate the pathophysiology of congenital hyperinsulinism
Download from link.springer.com
2020
Elisa De Franco ,
Cai Y.,
Lithovius V.,
Laver Tw,
Maria Lytrivi ,
Sawatani T.,
Hazem Ibrahim ,
Matthew N. Wakeling,
Hossam Montaser,
Godbole T.,
Senee V.,
Otonkoski T.,
Federica Fantuzzi,
De Franco E.,
Kashyap Patel
and 63 other authors
,
Cai Y.,
Lithovius V.,
Laver Tw,
Maria Lytrivi ,
Sawatani T.,
Hazem Ibrahim ,
Matthew N. Wakeling,
Hossam Montaser,
Godbole T.,
Senee V.,
Otonkoski T.,
Federica Fantuzzi,
De Franco E.,
Kashyap Patel
and 63 other authors
YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress
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Olof Asplund ,
Petter Storm,
Vikash Chandra ,
Gad Hatem,
Emilia Ottosson-Laakso,
Dina Mansour-Aly,
Ulrika Krus,
Hazem Ibrahim ,
Emma Ahlqvist,
Tiinamaija Tuomi ,
Erik Renström,
Olle Korsgren,
Nils Wierup,
Mark Ibberson,
Michele Solimena
and 9 other authors
,
Petter Storm,
Vikash Chandra ,
Gad Hatem,
Emilia Ottosson-Laakso,
Dina Mansour-Aly,
Ulrika Krus,
Hazem Ibrahim ,
Emma Ahlqvist,
Tiinamaija Tuomi ,
Erik Renström,
Olle Korsgren,
Nils Wierup,
Mark Ibberson,
Michele Solimena
and 9 other authors
Islet Gene View - A Tool to Facilitate Islet Research
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2019
Om Prakash Dwivedi ,
Mikko Lehtovirta,
Benoit Hastoy ,
Nicole A. J. Krentz ,
Vikash Chandra ,
Sandra Kleiner,
Fernando Abaitua,
Deepak Jain,
Nicola L. Beer,
Dwivedi Op,
Ann-Marie Richard,
Anu Suoranta,
Antje Grotz ,
Rashmi B. Prasad ,
Soren K. Thomsen
and 36 other authors
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Mikko Lehtovirta,
Benoit Hastoy ,
Nicole A. J. Krentz ,
Vikash Chandra ,
Sandra Kleiner,
Fernando Abaitua,
Deepak Jain,
Nicola L. Beer,
Dwivedi Op,
Ann-Marie Richard,
Anu Suoranta,
Antje Grotz ,
Rashmi B. Prasad ,
Soren K. Thomsen
and 36 other authors
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
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Henna Kallionpää,
Juhi Somani,
Soile Tuomela,
Ubaid Ullah,
Rafael de Albuquerque,
Tapio Lönnberg,
Elina Komsi,
Heli Siljander,
Jarno Honkanen,
Taina Härkönen,
Aleksandr Peet,
Vallo Tillmann,
Vikash Chandra,
Mahesh Kumar Anagandula,
Gun Frisk
and 6 other authors
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2018
Diego Balboa ,
Jonna Saarimäki-Vire,
Daniel Borshagovski,
Mantas Survila,
Päivi Lindholm ,
Emilia Galli ,
Solja Eurola,
Jarkko Ustinov,
Heli Grym,
Hanna Huopio,
Juha Partanen,
Kirmo Wartiovaara ,
Timo Otonkoski
,
Jonna Saarimäki-Vire,
Daniel Borshagovski,
Mantas Survila,
Päivi Lindholm ,
Emilia Galli ,
Solja Eurola,
Jarkko Ustinov,
Heli Grym,
Hanna Huopio,
Juha Partanen,
Kirmo Wartiovaara ,
Timo Otonkoski
Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes
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2017
Marta Martin-Lopez ,
Laura Maeso-Alonso,
Sandra Fuertes-Alvarez,
Diego Balboa ,
Virginia Rodríguez-Cortez,
Jere Weltner,
Inmaculada Diez-Prieto,
Andrew Davis,
Yaning Wu,
Timo Otonkoski ,
Elsa R. Flores,
Pablo Menéndez ,
Margarita M. Marques,
Maria C. Marin
Download from www.nature.com
,
Laura Maeso-Alonso,
Sandra Fuertes-Alvarez,
Diego Balboa ,
Virginia Rodríguez-Cortez,
Jere Weltner,
Inmaculada Diez-Prieto,
Andrew Davis,
Yaning Wu,
Timo Otonkoski ,
Elsa R. Flores,
Pablo Menéndez ,
Margarita M. Marques,
Maria C. Marin
Download from www.nature.com
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