James Murphy
Walter and Eliza Hall Institute of Medical Research
19 papers found
Refreshing results…
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization
Download from doi.orgA common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
Download from doi.orgMLKL deficiency protects against low-grade, sterile inflammation in aged mice
Download from www.nature.comEndothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria
Download from www.nature.comUbiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
Download from doi.orgFerroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis
Download from www.nature.comHuman RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis
Download from doi.orgStructural and functional analysis of target recognition by the lymphocyte adaptor protein LNK
Download from www.nature.comMechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
Download from doi.orgBAK core dimers bind lipids and can be bridged by them
Download from www.nature.comStructure-based mechanism of preferential complex formation by apoptosis signal–regulating kinases
UploadThe anticonvulsive Phenhydan® suppresses extrinsic cell death
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