David J. A. Wyllie

Papers authored by David J. A. Wyllie

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2012 S. McKay, Nh H. Griffiths, Pa A. Butters, Eb B. Thubron, Ge E. Hardingham, Dja J. A. Wyllie

Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist

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Marc-André Martel, Tomás J. Ryan, Karen F. S. Bell, Jill H. Fowler, Aoife McMahon, Bashayer Al-Mubarak, Noboru H. Komiyama, Karen Horsburgh, Peter C. Kind, David J. A. Wyllie

, Seth G. N. Grant, Giles E. Hardingham

The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults

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Bilada Bilican, Andrea Serio, Sami J. Barmada, Agnes Lumi Nishimura, Gareth J. Sullivan, Monica Carrasco, Hemali P. Phatnani, Clare A. Puddifoot, David Story, Judy Fletcher, In-Hyun Park, Brad A. Friedman, George Q. Daley, David J. A. Wyllie

, Giles E. Hardingham and 5 other authors

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability

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David J. A. Wyllie

, Stephen F. Traynelis

NMDA receptor permeation: a light in the tunnel

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A. C. McMahon, M. W. Barnett, T. S. O'Leary, P. N. Stoney, M. O. Collins, S. Papadia, J. S. Choudhary

, N. H. Komiyama, S. G. N. Grant, G. E. Hardingham, D. J. A. Wyllie

, P. C. Kind

SynGAP isoforms exert opposing effects on synaptic strength

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2011 Timothy O'Leary, David J. A. Wyllie

Neuronal homeostasis: Time for a change?

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H. J. Otton, A. Lawson McLean

, M. A. Pannozzo, C. H. Davies, D. J. A. Wyllie

Quantification of the Mg2+-induced potency shift of amantadine and memantine voltage-dependent block in human recombinant GluN1/GluN2A NMDARs

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R. Patani, Aj J. Hollins, Tm M. Wishart, Ca A. Puddifoot, S. Álvarez, S. Alvarez, Ar R. de Lera, Dj J. A. Wyllie

, Da A. S. Compston, Ra A. Pedersen, Th H. Gillingwater, Ge E. Hardingham, Nd D. Allen, S. Chandran

Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state.

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2010 Emma Louise Clayton, Nancy Sue, Karen Janet Smillie, Timothy O’Leary, Nicolai Bache, Giselle Cheung, Adam Robert Cole, David J. Wyllie

, Calum Sutherland, Phillip James Robinson

, Michael Alan Cousin

Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles

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Giles E. Hardingham, Rickie Patani, Paul Baxter, David J. Wyllie

, Siddharthan Chandran

Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration

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Frédéric Léveillé, Sofia Papadia, Michael Fricker, Karen F. S. Bell, Francesc X. Soriano, Marc-André Martel, Clare Puddifoot, Marlen Habel, David J. Wyllie

, Chrysanthy Ikonomidou, Aviva M. Tolkovsky, Giles E. Hardingham

Suppression of the intrinsic apoptosis pathway by synaptic activity

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Timothy O’Leary, Mark C. W. van Rossum, David J. A. Wyllie

Homeostasis of intrinsic excitability in hippocampal neurones: dynamics and mechanism of the response to chronic depolarization

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2009 Timothy O'Leary, David J A. Wyllie

, David J. A. Wyllie

Single-channel properties of N-methyl-D-aspartate receptors containing chimaeric GluN2A/GluN2D subunits

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Hannah J Otton, Ariane Janssen, David J A. Wyllie

Inhibition of recombinant GluN1/GluN2A and GluN1/GluN2B N-methyl-D-aspartate receptors by single malt whiskies

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Rickie Patani, Alastair Compston, Clare A. Puddifoot, David J. A. Wyllie

, Giles E. Hardingham, Nicholas D. Allen, Siddharthan Chandran

Activin/Nodal Inhibition Alone Accelerates Highly Efficient Neural Conversion from Human Embryonic Stem Cells and Imposes a Caudal Positional Identity

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Hannah J. Otton, Ariane Janssen, Timothy O'Leary, Philip E. Chen, David J. A. Wyllie

Inhibition of rat recombinant GluN1/GluN2A and GluN1/GluN2B NMDA receptors by ethanol at concentrations based on the US/UK drink-drive limit

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Ca Puddifoot, Pe Chen, R. Schoepfer, Dja Wyllie

Pharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed inXenopus laevisoocytes

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M.-A. Martel, D. J. A. Wyllie

, G. E. Hardingham

In developing hippocampal neurons, NR2B-containing N-methyl-d-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death

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2008 Timothy O'Leary, David J. A. Wyllie

The ups and downs of synaptic plasticity: influences on this particular ‘market’

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Francesc X. Soriano, Marc-Andre Martel, Sofia Papadia, Anne Vaslin, Paul Baxter, Colin Rickman, Joan Forder, Michael Tymianski, Rory Duncan, Michelle Aarts, Peter G. H. Clarke, David J. A. Wyllie

, Giles E. Hardingham

Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand

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Papers authored by David J. A. Wyllie