Brad Sleebs - Dissemin

Papers authored by Brad Sleebs

This paper is available in a repository.

2012 Nghi H. Nguyen, Brad E. Sleebs

, Jonathan M. White, Andrew B. Hughes

Corrigendum to “Diastereoselective synthesis of highly functionalized β2,2,3-substituted amino acids from 4-substituted-1,3-oxazinan-6-ones” [Tetrahedron 68 (2012) 4745–4756]

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Nghi H. Nguyen, Nghi H.; Sleebs, Brad E. Sleebs

, Jonathan M. White, Brad E.; Hughes, B. Andrew, Andrew B. Hughes

Diastereoselective Synthesis of Highly Functionalized β2,2,3‐Substituted Amino Acids from 4‐Substituted‐1,3‐oxazinan‐6‐ones.

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Brad E. Sleebs

, George Nikolakopoulos, Ian P. Street, Hendrik Falk, Jonathan B. Baell

Corrigendum to “Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitors” [Bioorg. Med. Chem. Lett. 21 (2011) 5992–5994]

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This paper was not found in any repository, but could be made available legally by the author.

2011 Brad E. Sleebs

, Peter E. Czabotar, Wayne J. Fairbrother, W. Douglas Fairlie, John A. Flygare, David C. S. Huang, Wilhelmus J. A. Kersten, Michael F. T. Koehler, Guillaume Lessene, Kym Lowes, John P. Parisot, Brian J. Smith, Morey L. Smith, Andrew J. Souers, Ian P. Street and 2 other authors

Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity

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Brad E. Sleebs

, Alla Levit, Ian P. Street, Hendrik Falk, Timothy Hammonds, Ai Ching Wong, Mark D. Charles, Michael F. Olson, Jonathan B. Baell

Identification of 3-aminothieno[2,3-b]pyridine-2-carboxamides and 4-aminobenzothieno[3,2-d]pyrimidines as LIMK1 inhibitors

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Brad E. Sleebs

, George Nikolakopoulos, Ian P. Street, Hendrik Falk, Jonathan B. Baell

Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitors

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Brad E. Sleebs

, Danny Ganame, Alla Levit, Ian P. Street, Alison Gregg, Hendrik Falk, Jonathan B. Baell

Development of substituted 7-phenyl-4-aminobenzothieno[3,2-d] pyrimidines as potent LIMK1 inhibitors

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Benny J. Evison, Mile Pastuovic, Rebecca A. Bilardi, Robert A. Forrest, Paul P. Pumuye, Brad E. Sleebs

, Keith G. Watson, Don R. Phillips, Suzanne M. Cutts

M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe.

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This paper is made freely available by the publisher.

2010 Brad Sleebs

, Ian Street, Xian Bu, Jonathan Baell

De novo synthesis of a potent LIMK1 inhibitor

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Oula C. Mansour, Benny J. Evison, Brad E. Sleebs

, Keith G. Watson, Abraham Nudelman, Ada-D.-A. Rephaeli, Damian P. Buck, J. Grant Collins, Rebecca A. Bilardi, Don R. Phillips, Suzanne M. Cutts

New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation.

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2009 Erinna F. Lee, Peter E. Czabotar, Hong Yang, Brad E. Sleebs

, Guillaume Lessene, Peter M. Colman, Brian John Smith, W. Douglas Fairlie

Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands*

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Brad E. Sleebs

, T. T. Van Nguyen, Andrew B. Hughes

Recent Advances in Stereoselective Synthesis and Application of β-Amino Acids

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2008 Andrew B. Hughes, Brad E. Sleebs

Studies of 2-Substituted 1,3-Oxazolidin-5-ones and 1,3-Oxazinan-6-ones as Precursors for the Synthesis ofN-Alkyl-β-Amino Acids

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Andrew B. Hughes, Brad E. Sleebs

Exploitation of the Arndt-Eistert Homologation of N-Methyl-�-Amino Acids for Concomitant Ester and N-Methyl Peptide Formation

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2007 Brad E. Sleebs

, Andrew B. Hughes

Diastereoselective Synthesis of α-Methyl and α-Hydroxy-β-amino Acids via 4-Substituted-1,3-oxazinan-6-ones.

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2006 Andrew B. Hughes, Brad E. Sleebs

Effective Methods for the Synthesis ofN-Methylβ-Amino Acids from All Twenty Commonα-Amino Acids Using 1,3-Oxazolidin-5-ones and 1,3-Oxazinan-6-ones

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2005 Andrew B. Hughes, Brad E. Sleebs

Synthesis of New β-Amino Acids via 5-Oxazolidinones and the Arndt-Eistert Procedure.

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2000 Luigi Aurelio, Robert T. C. Brownlee, Hughes Ab, Andrew B. Hughes, Brad E. Sleebs

The Facile Production of N-Methyl Amino Acids via Oxazolidinones

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Papers authored by Brad Sleebs