Philip Biggin
0000-0001-5100-8836
Oxford University
8 papers found
Refreshing results…
Small‐molecule positive allosteric modulation of homomeric kainate receptors GluK1‐3: development of screening assays and insight into GluK3 structure
Learning protein-ligand binding affinity with atomic environment vectors
A signal capture and proofreading mechanism for the KDEL-receptor explains selectivity and dynamic range in ER retrieval
State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane
A Refined Open State of the Glycine Receptor Obtained via Molecular Dynamics Simulations
Biomolecular simulations: From dynamics and mechanisms to computational assays of biological activity
Computational methods to examine conformational changes and ligand-binding properties: Examples in neurobiology
The startle disease mutation E103K impairs activation of human homomeric α1 glycine receptors by disrupting an intersubunit salt bridge across the agonist binding site
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