Thibault Mesplède

All papers authored by Thibault Mesplède

This paper is made freely available by the publisher.

2023 Cynthia Lungu

, Ronald J. Overmars, Esmée Grundeken, Patrick H. M. Boers, Marchina E. van der Ende, Thibault Mesplède

, Rob A. Gruters

Genotypic and Phenotypic Characterization of Replication-Competent HIV-2 Isolated from Controllers and Progressors

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Henrieke A. B. Prins

, Raquel Crespo

, Cynthia Lungu

, Shringar Rao, Letao Li

, Ronald J. Overmars, Grigorius Papageorgiou

, Yvonne M. Mueller

, Mateusz Stoszko

, Tanvir Hossain

, Tsung Wai Kan, Bart J. A. Rijnders

, Hannelore I. Bax, Eric C. M. van Gorp, Jan L. Nouwen

and 16 other authors

The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy

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2022 Jeroen J. A. van Kampen, Hanh Thi Pham, Sunbin Yoo, Ronald J. Overmars, Cynthia Lungu

, Rizwan Mahmud, Carolina A. M. Schurink, Sander van Boheemen

, Rob A. Gruters

, Pieter L. A. Fraaij, David M. Burger

, Jolanda J. C. Voermans, Casper Rokx

, David A. M. C. van de Vijver

, Thibault Mesplède

HIV-1 resistance against dolutegravir fluctuates rapidly alongside erratic treatment adherence: a case report

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This paper was not found in any repository, but could be made available legally by the author.

2020 Sandra Medina-Moreno, Juan C. Zapata, Fatah Kashanchi, Nhut M. Le, Said Hassounah, Thibault Mesplede

, Maureen Oliveira, Charles C. Davis, Alonso Heredia

Lamivudine-resistant HIVM184V is durably suppressed with dolutegravir plus lamivudine dual therapy in humanised mice

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2019 Yingshan Han

, Hanh T. Pham, Hongtao Xu, Yudong Quan, Thibault Mesplède

Antimalarial drugs and their metabolites are potent Zika virus inhibitors

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2018 Yingshan Han, Thibault Mesplède

Investigational drugs for the treatment of Zika virus infection: a preclinical and clinical update

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Hanh Thi Pham, Mark E. Goring, Thibault Mesplède

Reply to Achieng and Riedel

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2016 Ying-Shan Han, Thibault Mesplède

, Mark A. Wainberg

Differences among HIV-1 subtypes in drug resistance against integrase inhibitors

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Maureen Oliveira, Ruxandra I. Ibanescu, Hanh Thi Pham, Bluma Brenner, Thibault Mesplède

, Mark A. Wainberg

The M184I/V and K65R nucleoside resistance mutations in HIV-1 prevent the emergence of resistance mutations against dolutegravir:

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Thibault Mesplède

, Mark A. Wainberg

Will LEDGIN molecules be able to play a role in a cure for HIV infection?

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Hanh T. Pham, Thibault Mesplède

, Mark A. Wainberg

Effect on HIV-1 viral replication capacity of DTG-resistance mutations in NRTI/NNRTI resistant viruses

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Kaitlin Anstett, Vincent Cutillas, Robert Fusco, Thibault Mesplède

, Mark A. Wainberg

Polymorphic substitution E157Q in HIV-1 integrase increases R263K-mediated dolutegravir resistance and decreases DNA binding activity

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Bluma G. Brenner, Réjean Thomas, José Luis Blanco, Ruxandra-Ilinca Ibanescu, Maureen Oliveira, Thibault Mesplède

, Olga Golubkov, Michel Roger, Federico Garcia, Esteban Martinez, Mark A. Wainberg

Development of a G118R mutation in HIV-1 integrase following a switch to dolutegravir monotherapy leading to cross-resistance to integrase inhibitors

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Mark A. Wainberg, Ying-Shan Han, Thibault Mesplède

Might dolutegravir be part of a functional cure for HIV?

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2015 Mark A. Wainberg, Thibault Mesplede

Implications for the future of the HIV epidemic if drug resistance against dolutegravir cannot occur in first-line therapy

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Said A. Hassounah, Yannan Liu, Peter K. Quashie, Maureen Oliveira, Daniela Moisi, Bluma G. Brenner, Paul A. Sandstrom, Thibault Mesplède

, Mark A. Wainberg

Characterization of the Drug Resistance Profiles of Integrase Strand Transfer Inhibitors in Simian Immunodeficiency Virus SIVmac239

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Maureen Oliveira, Thibault Mesplède

, Daniela Moïsi, Ruxandra-Ilinca Ibanescu, Bluma Brenner, Mark A. Wainberg

The dolutegravir R263K resistance mutation in HIV-1 integrase is incompatible with the emergence of resistance against raltegravir

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Jiaming Liang, Thibault Mesplède

, Maureen Oliveira, Kaitlin Anstett, Mark A. Wainberg

The Combination of the R263K and T66I Resistance Substitutions in HIV-1 Integrase Is Incompatible with High-Level Viral Replication and the Development of High-Level Drug Resistance

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Kaitlin Anstett, Robert Fusco, Vincent Cutillas, Thibault Mesplède

, Mark A. Wainberg

Dolutegravir-Selected HIV-1 Containing the N155H and R263K Resistance Substitutions Does Not Acquire Additional Compensatory Mutations under Drug Pressure That Lead to Higher-Level Resistance and Increased Replicative Capacity

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Thibault Mesplède

, Mark A. Wainberg

Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV Persistence

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All papers authored by Thibault Mesplède