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All papers authored by Manolis Pasparakis

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2022 Huipeng Jiao

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, Laurens Wachsmuth

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, Juliane Lohmann, Masahiro Nagata, Göksu Gökberk Kaya

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, Nikos Oikonomou

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, Vangelis Kondylis

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, Martin Diebold

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, Simon E. Tröder

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, Branko Zevnik

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, Christoph Schell, George R. Young

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and 2 other authors

ADAR1 averts fatal type I interferon induction by ZBP1

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2021 Annika Hausmann

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, Leo Kunz

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, Dorothée Lisa Berthold

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, Nathan Sébastien Zangger

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, Toshihiro Nakamura

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, Tamas Dolowschiak

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, Stefan Alexander Fattinger

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, Katerina Vlantis

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, Markus Furter

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, Laurens Wachsmuth

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and 12 other authors

Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF

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2020 Huipeng Jiao, Laurens Wachsmuth

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, Snehlata Kumari

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, Robin Schwarzer, Juan Lin, Remzi Onur Eren, Amanda Fisher, Rebecca Lane, George R. Young

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, George Kassiotis, William J. Kaiser, Manolis Pasparakis

ORCID

Publisher Correction: Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation

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Huipeng Jiao, Laurens Wachsmuth

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, Snehlata Kumari

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, Robin Schwarzer, Juan Lin, Remzi Onur Eren, Amanda Fisher, Rebecca Lane, George R. Young

ORCID

, George Kassiotis, William J. Kaiser, Manolis Pasparakis

ORCID

Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation

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2019 Najoua Lalaoui, Steven E. Boyden, Hirotsugu Oda, Geryl M. Wood, Deborah L. Stone, Diep Chau, Lin Liu, Monique Stoffels, Tobias Kratina, Kate E. Lawlor, Kristien J. M. Zaal, Patrycja M. Hoffmann, Nima Etemadi, Kristy Shield-Artin, Christine Biben and 39 other authors

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

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Thomas MacVicar, Yohsuke Ohba, Hendrik Nolte, Fiona Carola Mayer, Takashi Tatsuta, Hans-Georg Sprenger, Barbara Lindner, Yue Zhao, Jiahui Li, Christiane Bruns, Marcus Krüger, Markus Habich, Jan Riemer, Robin Schwarzer, Manolis Pasparakis

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and 4 other authors

Lipid signalling drives proteolytic rewiring of mitochondria by YME1L

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Melanie Fritsch, Saskia D. Günther, Robin Schwarzer, Marie-Christine Albert, Fabian Schorn, J. Paul Werthenbach, Lars M. Schiffmann, Neil Stair, Hannah Stocks, Jens M. Seeger, Mohamed Lamkanfi, Martin Krönke, Manolis Pasparakis

ORCID

, Hamid Kashkar

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

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Lien Verboom, Arne Martens, Dario Priem, Mozes Sze, Hanna Vikkula, Lisette Van Hove, Sofie Voet, Jana Roels, Jonathan Maelfait, Alain de Bruin, Charlotte L. Scott, Yvan Saeys, Manolis Pasparakis

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, Bertrand Mj, Geert van Loo and 4 other authors

OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis

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Christina Eftychi, Robin Schwarzer, Katerina Vlantis, Laurens Wachsmuth

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, Marijana Basic, Prerana Wagle, Markus F. Neurath, Christoph Becker

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, André Bleich, Manolis Pasparakis

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Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment

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Santosh Krishna-Subramanian

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, Stephan Singer, Marietta Armaka

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, Jesus M. Banales

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, Kerstin Holzer, Peter Schirmacher, Henning Walczak

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, George Kollias

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, Manolis Pasparakis

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, Vangelis Kondylis

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RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury

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Jessica Gräb, Isabelle Suárez, Edeltraud van Gumpel, Sandra Winter, Fynn Schreiber, Anna Esser, Christoph Hölscher, Melanie Fritsch, Marc Herb

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, Michael Schramm, Laurens Wachsmuth

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, Christian Pallasch

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, Manolis Pasparakis

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, Hamid Kashkar, Jan Rybniker

Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition

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Vasiliki Koliaraki, Niki Chalkidi, Ana Henriques, Christos Tzaferis, Apostolos Polykratis, Ari Waisman, Werner Muller, David J. Hackam, Manolis Pasparakis

ORCID

, George Kollias

Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis

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2018 Gianmaria Liccardi, Laura Ramos Garcia, Tencho Tenev, Alessandro Annibaldi, Arnaud J. Legrand, David Robertson, Rebecca Feltham, Holly Anderton, Maurice Darding, Nieves Peltzer, Marius Dannappel, Hannah Schünke, Luca L. Fava, Manuel D. Haschka, Timo Glatter and 10 other authors

RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation

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Akshay A. D'Cruz, Mary Speir, Meghan Bliss-Moreau, Sylvia Dietrich, Alyce A. Chen, Mathilde Gavillet, Kate E. Lawlor, James E. Vince, Michelle Kelliher, Razq Hakem, Manolis Pasparakis

ORCID

, David A. Williams, Maria Ericsson, Ben A. Croker

Padi4 Regulates NET Formation and Inflammatory Cell Death Downstream of Mlkl

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Alessandro Torgovnick, Jan Michel Heger, Vasiliki Liaki, Jörg Isensee, Anna Schmitt, Gero Knittel, Arina Riabinska, Filippo Beleggia, Lucie Laurien, Uschi Leeser, Christian Jüngst

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, Florian Siedek, Wenzel Vogel, Niklas Klümper, Hendrik Nolte and 13 other authors

The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression

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Konrad Aden, Florian Tran

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, Go Ito, Raheleh Sheibani-Tezerji, Simone Lipinski

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, Jan W. Kuiper, Markus Tschurtschenthaler

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, Svetlana Saveljeva, Joya Bhattacharyya

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, Robert Häsler, Kareen Bartsch, Anne Luzius, Marlene Jentzsch, Maren Falk-Paulsen, Stephanie T. Stengel and 11 other authors

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING

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Lucia Taraborrelli, Nieves Peltzer, Antonella Montinaro, Sebastian Kupka, Eva Rieser, Torsten Hartwig, Aida Sarr, Maurice Darding, Peter Draber, Tobias L. Haas, Ayse Akarca, Teresa Marafioti, Manolis Pasparakis

ORCID

, John Bertin, Peter J. Gough

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and 5 other authors

LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L

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Manolis Pasparakis

ORCID

, Michelle Kelliher

Connecting immune deficiency and inflammation

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Marietta Armaka

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, Caroline Ospelt, Manolis Pasparakis

ORCID

, George Kollias

The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts

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Lorenzo Galluzzi, Ilio Vitale

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, Stuart A. Aaronson, John M. Abrams, Dieter Adam, Patrizia Agostinis, Emad S. Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, Margherita Annicchiarico-Petruzzelli, Alexey V. Antonov, Eli Arama, Eric H. Baehrecke, Nickolai A. Barlev and 154 other authors

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

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