All papers authored by Jim Hughes
Refreshing results…
2023
Damien J. Downes 
,
Alastair L. Smith ,
Magdalena A. Karpinska ,
Taras Velychko ,
Kevin Rue-Albrecht ,
David Sims,
Thomas A. Milne ,
James O. J. Davies ,
A. Marieke Oudelaar ,
Jim R. Hughes
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,
Alastair L. Smith ,
Magdalena A. Karpinska ,
Taras Velychko ,
Kevin Rue-Albrecht ,
David Sims,
Thomas A. Milne ,
James O. J. Davies ,
A. Marieke Oudelaar ,
Jim R. Hughes
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Mohsin Badat ,
Ayesha Ejaz,
Peng Hua ,
Siobhan Rice,
Weijiao Zhang,
Lance D. Hentges ,
Christopher A. Fisher,
Nicholas Denny ,
Ron Schwessinger,
Nirmani Yasara ,
Noemi B. A. Roy,
Fadi Issa ,
Andi Roy ,
Paul Telfer,
Jim Hughes
and 3 other authors
,
Ayesha Ejaz,
Peng Hua ,
Siobhan Rice,
Weijiao Zhang,
Lance D. Hentges ,
Christopher A. Fisher,
Nicholas Denny ,
Ron Schwessinger,
Nirmani Yasara ,
Noemi B. A. Roy,
Fadi Issa ,
Andi Roy ,
Paul Telfer,
Jim Hughes
and 3 other authors
Direct correction of haemoglobin E β-thalassaemia using base editors
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2021
Jennifer C. Herrmann,
Robert A. Beagrie ,
Jim R. Hughes
,
Jim R. Hughes
Making connections: enhancers in cellular differentiation
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Andrew J. King,
Duantida Songdej ,
Damien J. Downes ,
Robert A. Beagrie ,
Siyu Liu,
Megan Buckley ,
Peng Hua ,
Maria C. Suciu,
A. Marieke Oudelaar ,
Lars L. P. Hanssen,
Danuta Jeziorska,
Nigel Roberts ,
Stephanie J. Carpenter,
Helena Francis ,
Jelena Telenius
and 11 other authors
,
Damien J. Downes ,
Robert A. Beagrie ,
Siyu Liu,
Megan Buckley ,
Peng Hua ,
Maria C. Suciu,
A. Marieke Oudelaar ,
Lars L. P. Hanssen,
Danuta Jeziorska,
Nigel Roberts ,
Stephanie J. Carpenter,
Helena Francis ,
Jelena Telenius
and 11 other authors
Reactivation of a developmentally silenced embryonic globin gene
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Peng Hua ,
Mohsin Badat ,
Lars L. P. Hanssen ,
Lance D. Hentges ,
Nicholas Crump ,
Damien J. Downes ,
Danuta M. Jeziorska,
A. Marieke Oudelaar,
A. Marieke Oudelaar ,
Ron Schwessinger ,
Stephen Taylor ,
Thomas A. Milne ,
Jim R. Hughes ,
Doug R. Higgs ,
James O. J. Davies
,
Mohsin Badat ,
Lars L. P. Hanssen ,
Lance D. Hentges ,
Nicholas Crump ,
Damien J. Downes ,
Danuta M. Jeziorska,
A. Marieke Oudelaar,
A. Marieke Oudelaar ,
Ron Schwessinger ,
Stephen Taylor ,
Thomas A. Milne ,
Jim R. Hughes ,
Doug R. Higgs ,
James O. J. Davies
Defining genome architecture at base-pair resolution
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Damien J. Downes ,
Robert A. Beagrie ,
Matthew E. Gosden ,
Jelena Telenius,
Stephanie J. Carpenter,
Lea Nussbaum,
Sara De Ornellas,
Martin Sergeant,
Chris Q. Eijsbouts,
Ron Schwessinger ,
Jon Kerry,
Nigel Roberts ,
Arun Shivalingam,
Afaf El-Sagheer ,
A. Marieke Oudelaar
and 4 other authors
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,
Robert A. Beagrie ,
Matthew E. Gosden ,
Jelena Telenius,
Stephanie J. Carpenter,
Lea Nussbaum,
Sara De Ornellas,
Martin Sergeant,
Chris Q. Eijsbouts,
Ron Schwessinger ,
Jon Kerry,
Nigel Roberts ,
Arun Shivalingam,
Afaf El-Sagheer ,
A. Marieke Oudelaar
and 4 other authors
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2020
A. Marieke Oudelaar,
Robert A. Beagrie ,
Matthew Gosden ,
Sara de Ornellas ,
Emily Georgiades ,
Jon Kerry,
Daniel Hidalgo ,
Joana Carrelha,
Arun Shivalingam,
Afaf H. El-Sagheer ,
Jelena M. Telenius,
Tom Brown ,
Veronica J. Buckle ,
Merav Socolovsky ,
Douglas R. Higgs
and 1 other authors
,
Matthew Gosden ,
Sara de Ornellas ,
Emily Georgiades ,
Jon Kerry,
Daniel Hidalgo ,
Joana Carrelha,
Arun Shivalingam,
Afaf H. El-Sagheer ,
Jelena M. Telenius,
Tom Brown ,
Veronica J. Buckle ,
Merav Socolovsky ,
Douglas R. Higgs
and 1 other authors
Dynamics of the 4D genome during in vivo lineage specification and differentiation
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2019
A. Marieke Oudelaar ,
Caroline L. Harrold ,
Lars L. P. Hanssen ,
Jelena M. Telenius ,
Douglas R. Higgs ,
Jim R. Hughes
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,
Caroline L. Harrold ,
Lars L. P. Hanssen ,
Jelena M. Telenius ,
Douglas R. Higgs ,
Jim R. Hughes
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Laura Godfrey ,
Nicholas T. Crump ,
Ross Thorne,
I.-Jun Lau,
Emmanouela Repapi ,
Dimitra Dimou,
Alastair L. Smith ,
Joe R. Harman ,
Jelena M. Telenius,
A. Marieke Oudelaar ,
Damien J. Downes,
Paresh Vyas ,
Jim R. Hughes ,
Thomas A. Milne
,
Nicholas T. Crump ,
Ross Thorne,
I.-Jun Lau,
Emmanouela Repapi ,
Dimitra Dimou,
Alastair L. Smith ,
Joe R. Harman ,
Jelena M. Telenius,
A. Marieke Oudelaar ,
Damien J. Downes,
Paresh Vyas ,
Jim R. Hughes ,
Thomas A. Milne
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation
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Joke G. van Bemmel ,
Rafael Galupa ,
Chris Gard,
Nicolas Servant ,
Christel Picard,
James Davies ,
Anthony James Szempruch,
Yinxiu Zhan ,
Jan J. Żylicz ,
Elphège P. Nora ,
Sonia Lameiras,
Elzo de Wit ,
David Gentien ,
Sylvain Baulande ,
Luca Giorgetti
and 5 other authors
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,
Rafael Galupa ,
Chris Gard,
Nicolas Servant ,
Christel Picard,
James Davies ,
Anthony James Szempruch,
Yinxiu Zhan ,
Jan J. Żylicz ,
Elphège P. Nora ,
Sonia Lameiras,
Elzo de Wit ,
David Gentien ,
Sylvain Baulande ,
Luca Giorgetti
and 5 other authors
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Pei Jin Lim,
Tiago L. Duarte ,
João Arezes,
Daniel Garcia-Santos,
Amel Hamdi,
Sant-Rayn Pasricha,
Andrew E. Armitage ,
Hema Mehta,
Sarah Wideman ,
Ana G. Santos,
Andreia Santos-Gonçalves,
Alireza Morovat ,
Jim R. Hughes ,
Elizabeth Soilleux,
Chia-Yu Wang
and 9 other authors
,
João Arezes,
Daniel Garcia-Santos,
Amel Hamdi,
Sant-Rayn Pasricha,
Andrew E. Armitage ,
Hema Mehta,
Sarah Wideman ,
Ana G. Santos,
Andreia Santos-Gonçalves,
Alireza Morovat ,
Jim R. Hughes ,
Elizabeth Soilleux,
Chia-Yu Wang
and 9 other authors
Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin
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2018
A. Marieke Oudelaar,
James O. J. Davies,
Lars L. P. Hanssen ,
Jelena M. Telenius ,
Ron Schwessinger ,
Yu Liu ,
Jill M. Brown ,
Damien J. Downes,
Andrea M. Chiariello,
Simona Bianco ,
Mario Nicodemi ,
Veronica J. Buckle ,
Job Dekker ,
Douglas R. Higgs ,
Jim R. Hughes
,
Jelena M. Telenius ,
Ron Schwessinger ,
Yu Liu ,
Jill M. Brown ,
Damien J. Downes,
Andrea M. Chiariello,
Simona Bianco ,
Mario Nicodemi ,
Veronica J. Buckle ,
Job Dekker ,
Douglas R. Higgs ,
Jim R. Hughes
Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains
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2017
Sachith Mettananda ,
Chris A. Fisher,
Deborah Hay,
Lynn Quek,
Kevin Clark,
Philip Hublitz,
Damien Downes,
Jon Kerry,
Matthew Gosden,
Jelena Telenius,
Jackie A. Sloane-Stanley,
Paula Faustino,
Andreia Coelho,
Jessica Doondeea,
Batchimeg Usukhbayar
and 7 other authors
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,
Chris A. Fisher,
Deborah Hay,
Lynn Quek,
Kevin Clark,
Philip Hublitz,
Damien Downes,
Jon Kerry,
Matthew Gosden,
Jelena Telenius,
Jackie A. Sloane-Stanley,
Paula Faustino,
Andreia Coelho,
Jessica Doondeea,
Batchimeg Usukhbayar
and 7 other authors
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2016
Wen Fong Ooi,
Manjie Xing,
Chang Xu,
Xiaosai Yao ,
Muhammad Khairul Ramlee,
Mei Chee Lim,
Fan Cao,
Kevin Lim ,
Deepak Babu,
Lai-Fong Poon,
Joyce Lin Suling,
Aditi Qamra,
Astrid Irwanto,
James Qu Zhengzhong,
Tannistha Nandi
and 20 other authors
,
Muhammad Khairul Ramlee,
Mei Chee Lim,
Fan Cao,
Kevin Lim ,
Deepak Babu,
Lai-Fong Poon,
Joyce Lin Suling,
Aditi Qamra,
Astrid Irwanto,
James Qu Zhengzhong,
Tannistha Nandi
and 20 other authors
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity
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