Adam Shapiro - Dissemin

All papers authored by Adam Shapiro

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2017 Thomas F. Durand-Réville, Satenig Guler, Janelle Comita-Prevoir, Brendan Chen, Neil Bifulco, Hoan Huynh, Sushmita Lahiri, Adam B. Shapiro

, Sarah M. McLeod, Nicole M. Carter, Samir H. Moussa

, Camilo Velez-Vega, Nelson B. Olivier, Robert McLaughlin, Ning Gao and 11 other authors

ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2016 David C. McKinney, Charles J. Eyermann, Rong-Fang Gu, Jun Hu, Steven L. Kazmirski, Sushmita D. Lahiri, Andrew R. McKenzie, Adam B. Shapiro

, Gloria Breault

Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping

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Adam B. Shapiro

Investigation of β-lactam antibacterial drugs, β-lactamases, and penicillin-binding proteins with fluorescence polarization and anisotropy: a review

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This paper was not found in any repository, but could be made available legally by the author.

2015 Sebastian Imstepf, Vanessa Pierroz, Paula Raposinho, Matthias Bauwens, Michael Felber, Thomas Fox, Adam B. Shapiro

, Robert Freudenberg, Célia Fernandes, Sofia Gama, Gilles Gasser

, Felix Motthagy, Isabel R. Santos, Roger Alberto

Nuclear Targeting with an Auger Electron Emitter Potentiates the Action of a Widely Used Antineoplastic Drug

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Jonathan A. Rose, Sushmita D. Lahiri, David C. McKinney, Rob Albert, Marshall L. Morningstar, Adam B. Shapiro

, Stewart L. Fisher, Paul R. Fleming

Novel broad-spectrum inhibitors of bacterial methionine aminopeptidase

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Michael R. Hale, Claire Brassington, Dan Carcanague, Kevin Embrey, Charles J. Eyermann, Robert A. Giacobbe, Lakshmaiah Gingipalli, Madhusudhan Gowravaram, Jenna Harang, Tina Howard, Georgine Ioannidis, Haris Jahic, Amy Kutschke, Valerie A. Laganas, James Loch

and 7 other authors

From fragments to leads: novel bacterial NAD+-dependent DNA ligase inhibitors

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Kerry E. Murphy-Benenato, Pratik R. Bhagunde, April Chen, Hajnalka E. Davis, Thomas F. Durand-Réville, David E. Ehmann, Vincent Galullo, Jennifer J. Harris, Holia Hatoum-Mokdad, Haris Jahić, Aryun Kim, M. R. Manjunatha, Erika L. Manyak, John Mueller, Sara Patey and 11 other authors

Discovery of EfficaciousPseudomonas aeruginosa-Targeted Siderophore-Conjugated Monocarbams by Application of a Semi-mechanistic Pharmacokinetic/Pharmacodynamic Model

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William F. Penwell, William A. Penwell, Adam B. Shapiro

, Robert A. Giacobbe, Rong-Fang Gu, Ning Gao, Jason Thresher, Robert E. McLaughlin, Michael D. Huband, Boudewijn L. M. DeJonge, David E. Ehmann, Alita A. Miller

Molecular Mechanisms of Sulbactam Antibacterial Activity and Resistance Determinants in Acinetobacter baumannii

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2014 Adam B. Shapiro

, Ning Gao, Nichole O'Connell, Nichole O’Connell, Jun Hu, Jason Thresher, Rong-Fang Gu, Ross Overman

, Ian M. Hardern, Graham G. Sproat

Quantitative investigation of the affinity of human respiratory syncytial virus phosphoprotein C-terminus binding to nucleocapsid protein

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Asha S. Nayar, Thomas J. Dougherty, Folkert Reck, Jason Thresher, Ning Gao, Adam B. Shapiro

, David E. Ehmann

Target-Based Resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a Novel Bacterial Type II Topoisomerase Inhibitor

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Adam B. Shapiro

, Ning Gao, Rong-Fang Gu, Jason Thresher

Fluorescence anisotropy-based measurement of Pseudomonas aeruginosa penicillin-binding protein 2 transpeptidase inhibitor acylation rate constants

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Adam B. Shapiro

, Rong-Fang Gu, Ning Gao

Dimerization of isolated Pseudomonas aeruginosa lipopolysaccharide transporter component LptA

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Ayome Abibi, Andrew D. Ferguson, Paul R. Fleming, Ning Gao, Laurel I. Hajec, Jun Hu, Valerie A. Laganas, David C. McKinney, Sarah M. McLeod, D. Bryan Prince, Adam B. Shapiro

, Ed T. Buurman

The Role of a Novel Auxiliary Pocket in Bacterial Phenylalanyl-tRNA Synthetase Druggability

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Adam B. Shapiro

Complete steady-state rate equation for DNA ligase and its use for measuring product kinetic parameters of NAD+-dependent DNA ligase from Haemophilus influenzae

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2013 Adam B. Shapiro

, Caroline A. Austin

A high-throughput fluorescence anisotropy-based assay for human topoisomerase II β-catalyzed ATP-dependent supercoiled DNA relaxation

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Adam B. Shapiro

, Rong-Fang Gu, Ning Gao, Stephania Livchak, Jason Thresher

Continuous fluorescence anisotropy-based assay of BOCILLIN FL penicillin reaction with penicillin binding protein 3

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Adam B. Shapiro

, Joseph Newman, Kosalaram Goteti, Marie-Eve Beaudoin, Rane Harrison, Sussie Hopkins, Nikunj Agrawal, Olga Rivin

Improvement of the Pharmacokinetics andIn VivoAntibacterial Efficacy of a Novel Type IIa Topoisomerase Inhibitor by Formulation in Liposomes

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Adam B. Shapiro

A high-throughput-compatible, fluorescence anisotropy-based assay for ATP-dependent supercoiled DNA relaxation by human topoisomerase IIα

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2012 Adam B. Shapiro

, Ning Gao, Laurel Hajec, David C. McKinney

Time-dependent, reversible, oxaborole inhibition of Escherichia coli leucyl-tRNA synthetase measured with a continuous fluorescence assay

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Suzanne S. Stokes, Robert Albert, Ed T. Buurman, Beth Andrews, Adam B. Shapiro

, Oluyinka M. Green, Andrew R. McKenzie, Ludovic R. Otterbein

Inhibitors of the acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridylyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 2: Optimization of physical properties leading to antibacterial aryl sulfonamides

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All papers authored by Adam Shapiro