Andreas Plückthun

Papers authored by Andreas Plückthun

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2013 Christian Reichen, Simon Hansen, Andreas Plückthun

Modular Peptide Binding: From a Comparison of Natural Binders to Designed Armadillo Repeat Proteins.

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V. Chandana Epa, V. Chandana Epa, Olan Dolezal, Larissa Doughty, Xiaowen Xiao, Christian Jost

, Andreas Plückthun

, Timothy E. Adams

Structural Model for the Interaction of a Designed Ankyrin Repeat Protein with the Human Epidermal Growth Factor Receptor 2

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Lutz Kummer, Daniel J. Scott, Andreas Plückthun

, Dirk Tremmel

Stabilizing membrane proteins through protein engineering

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Christian Jost

, Johannes Schilling, Rastislav Tamaskovic, Martin Schwill, Annemarie Honegger, A. Plueckthun, Andreas Plückthun

Structural basis for eliciting a cytotoxic effect in HER2-overexpressing cancer cells via binding to the extracellular domain of HER2

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Katrin Friedrich, Jan Rh H. Hanauer, Steffen Prüfer, Robert C. Münch, Christodoulos Filippis, Iris Völker, Kay-Martin Hanschmann, Christian Jost

, Roberto Cattaneo, Kah-Whye Peng, Christian J. Buchholz, Andreas Plückthun

, Klaus Cichutek, Michael D. Mühlebach

DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety

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Benoît Gigant, Birgit Dreier, Weiyi Wang, Qiyang Jiang, Ludovic Pecqueur, Andreas Plückthun

, Chunguang Wang, Marcel Knossow

Structure of a kinesin-tubulin complex and implications for kinesin motility

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Andreas Plückthun

, Karola M. Schlinkmann

Directed evolution of G-protein-coupled receptors for high functional expression and detergent stability

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Mikaela Friedman, Gucci Jijuan Gu, Kai Johnsson, Christian Jost

, Masood Kamali-Moghaddam, Ulf Landegren, Andreas Plückthun

, Ola Söderberg

Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation

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Manuel Simon, Andreas Plückthun

, Nikolas Stefan, Uwe Zangemeister-Wittke

Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy

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Birgit Dreier, Annemarie Honegger, Christian Hess, Markus G. Grütter, Peer R. E. Mittl, Gabriela Nagy-Davidescu, Natalya Belousova, Galina Mikheeva, Victor Krasnykh, Andreas Plückthun

Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters

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Manuel Simon, Raphael Frey, Andreas Plückthun

, Uwe Zangemeister-Wittke

Orthogonal assembly of a designed ankyrin repeat protein-cytotoxin conjugate with a clickable serum albumin module for half-life extension

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Andreas Plückthun

, Daniel J. Scott

Direct molecular evolution of detergent-stable G protein-coupled receptors using polymer encapsulated cells

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Lutz Kummer, Onur Dagliyan, Chia-Wen Hsu, Christopher Macnevin, Melanie Kaufholz, Nikolay V. Dokholyan, Bastian Zimmermann, Klaus M. Hahn, Andreas Plückthun

Knowledge-based design of a biosensor to quantify localized ERK activation in living cells

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Axel Mann, Nikolas Friedrich, Anders Krarup, Jacqueline Weber, Birgit Dreier, Emanuel Stiegeler, Pavel Pugach, Melissa Robbiani, Tina Riedel, Kerstin Moehle, John A. Robinson, Peter Rusert, Andreas Plückthun

, Alexandra Trkola

Conformation-dependent recognition of HIV gp120 by designed ankyrin repeat proteins provides access to novel HIV entry inhibitors

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2012 Ap Frei, Oy Jeon, Samuel Kilcher, Hansjoerg Moest, Lm Henning, Christian Jost

, Andreas Plückthun

, Jason Mercer, Ruedi Aebersold, Em Carreira

, Bernd Wollscheid

Direct identification of ligand-receptor interactions on living cells and tissues.

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Lutz Kummer, Petra Parizek, Peter Rube, Bastian Millgramm, Peer R. E. Mittl, Anke Prinz, Melanie Kaufholz, Friedrich W. Herberg, Bastian Zimmermann, Andreas Plückthun

Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein libraries

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Ingrid Mignot, Ludovic Pecqueur, Audrey Dorléans, Manikandan Karuppasamy, Raimond B. G. Ravelli, Birgit Dreier, Benoît Gigant, Marcel Knossow, Andreas Plückthun

Design and Characterization of Modular Scaffolds for Tubulin Assembly*

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Ludovic Pecqueur, Christian Duellberg, Birgit Dreier, Qiyang Jiang, Chunguang Wang, Andreas Plückthun

, Thomas Surrey

, Benoît Gigant, Marcel Knossow

A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end

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Karola M. Schlinkmann, Matthias Hillenbrand, Alexander Rittner, Madeleine Künz, Ralf Strohner, Andreas Plückthun

Maximizing Detergent Stability and Functional Expression of a GPCR by Exhaustive Recombination and Evolution

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Karola M. Schlinkmann, Annemarie Honegger, Esin Türeci, Keith E. Robison, Daša Lipovšek, Andreas Plückthun

Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-all mutations

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Papers authored by Andreas Plückthun