Jeremy C. Mottram

Papers authored by Jeremy C. Mottram

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1998 Jeremy C. Mottram

Leishmania mexicana cysteine proteinase-deficient mutants have attenuated virulence for mice and potentiate a Th1 response.

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Jeremy C. Mottram

, Graham H. Coombs

Leishmania Cysteine Proteinases: Virulence Factors in Quest of a Function—Reply

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Jeremy C. Mottram

, Darren R. Brooks, Graham H. Coombs

Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions

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1997 Genevieve Bart, Mhairi J. Frame, Roderick Carter, Graham H. Coombs, Jeremy C. Mottram

Cathepsin B-like cysteine proteinase-deficient mutants of Leishmania mexicana

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Jeremy C. Mottram

, Mhairi J. Frame, Darren R. Brooks, Laurence Tetley, J. Elizabeth Hutchison, Souza Ae, Augustine E. Souza, Graham H. Coombs

The Multiple cpb Cysteine Proteinase Genes ofLeishmania mexicana Encode Isoenzymes That Differ in Their Stage Regulation and Substrate Preferences

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G. H. Coombs, Jeremy C. Mottram

Parasite proteinases and amino acid metabolism: possibilities for chemotherapeutic exploitation.

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J. H. Kinnaird, J. C. Mottram

Plasmodium cdc2-related kinases: Do they regulate stage differentiation?

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1996 Jeremy C. Mottram

, B. Philomena McCready, Kathryn G. Brown, Karen M. Grant

Gene disruptions indicate an essential function for the LmmCRK1 cdc2-related kinase of Leishmania mexicana

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Jeremy C. Mottram

, Karen M. Grant

Leishmania mexicana p12cks1, a homologue of fission yeast p13suc1, associates with a stage-regulated histone H1 kinase.

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J. C. Mottram

, A. E. Souza, J. E. Hutchison, R. Carter, M. J. Frame, G. H. Coombs

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

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1995 Jeremy C. Mottram

, Gareth Smith

A family of trypanosome cdc2-related protein kinases

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Genevieve Bart, Graham H. Coombs, Jeremy C. Mottram

Isolation of lmcpc, a gene encoding a Leishmania mexicana cathepsin-B-like cysteine proteinase

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Markus Wolfram, Thomas Ilg, Jeremy C. Mottram

, Peter Overath

Antigen presentation byLeishmania mexicana-infected macrophages: Activation of helper T cells specific for amastigote cysteine proteinases requires intracellular killing of the parasites

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1994 Augustine E. Souza, Paul A. Bates, Graham H. Coombs, Jeremy C. Mottram

Null mutants for the lmcpa cysteine proteinase gene in Leishmania mexicana

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J. C. Mottram

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1993 B. R. Shiels, J. H. Kinnaird, Jeremy C. Mottram

, A. Tait, J. D. Barry

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1992 Augustine E. Souza, Sheila Waugh, Graham H. Coombs, Jeremy C. Mottram

Characterization of a multi-copy gene for a major stage-specific cysteine proteinase ofLeishmania mexicana

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Howard A. Baylis, Anne Megson, Jeremy C. Mottram

, Roger Hall

Characterisation of a gene for a cysteine protease from Theileria annulata

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Jeremy C. Mottram

, Colin D. Robertson, Graham H. Coombs, J. David Barry

A developmentally regulated cysteine proteinase gene of Leishmania mexicana

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1991 R. G. Nelson, S. D. Bell, Jeremy C. Mottram

, J. D. Barry

tRNAs of Trypanosoma brucei. Unusual gene organization and mitochondrial importation.

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Papers authored by Jeremy C. Mottram