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Papers authored by Timothy Frayling

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2013 Andrew R. Wood, John R. B. Perry, Toshiko Tanaka, Dena G. Hernandez, Hou-Feng Zheng, David Melzer

ORCID

, J. Raphael Gibbs, J. Raphael Gibbs, Michael A. Nalls, Michael N. Weedon

ORCID

, Tim D. Spector, J. Brent Richards, J. Brent Richards, Stefania Bandinelli, Luigi Ferrucci and 2 other authors

Imputation of Variants from the 1000 Genomes Project Modestly Improves Known Associations and Can Identify Low-frequency Variant - Phenotype Associations Undetected by HapMap Based Imputation

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Hanieh Yaghootkar, Timothy M. Frayling

ORCID

Recent progress in the use of genetics to understand links between type 2 diabetes and related metabolic traits

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2012 T. M. Frayling

ORCID

Are the causes of obesity primarily environmental? No

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M. Islam, Th H. Jafar, Ar R. Wood, Nm M. G. De Silva, M. Caulfield, N. Chaturvedi, Tm M. Frayling

ORCID

Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis.

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2011 Yingleong Chan, Oddgeir L. Holmen, Andrew Dauber, Lars Vatten, Aki S. Havulinna, Frank Skorpen, Kirsti Kvaloy, Kaisa Silander, Thutrang T. Nguyen, Cristen Willer, Michael Boehnke, Markus Perola, Aarno Palotie, Veikko Salomaa, Kristian Hveem and 3 other authors

Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals

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Andrew R. Wood, Dena G. Hernandez, Michael A. Nalls, Hanieh Yaghootkar, J. Raphael Gibbs, J. Raphael Gibbs, Lorna W. Harries, Sean Chong, Matthew Moore, Michael N. Weedon

ORCID

, Jack M. Guralnik, Stefania Bandinelli, Anna Murray, Luigi Ferrucci, Andrew B. Singleton and 2 other authors

Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association

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Nm Maneka G. De Silva, N. Maneka G. De Silva, Rachel M. Freathy

ORCID

, Tom M. Palmer, Louise A. Donnelly, Jian'an Luan, Tom Gaunt

ORCID

, Claudia Langenberg, Michael N. Weedon

ORCID

, Beverley Shields, Beatrice A. Knight, Kirsten J. Ward, Manjinder S. Sandhu, Roger M. Harbord, Mark I. McCarthy and 8 other authors

Mendelian Randomization Studies Do Not Support a Role for Raised Circulating Triglyceride Levels Influencing Type 2 Diabetes, Glucose Levels, or Insulin Resistance

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Timothy M. Frayling

ORCID

, Ken Ong

Piecing together the FTO jigsaw

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2010 Joyce B. J. vVan Meurs, Joyce B. Jb van Meurs, Gert-Jan van Ommen, Cornelia M. van Duijn, Hana Lango Allen, Karol Estrada, Guillaume Lettre, Berndt Si, Hana Lango Allen, Weedon Mn, Sonja I. Berndt, Fernando Rivadeneira, Michael N. Weedon

ORCID

, Willer Cj, Jackson Au and 440 other authors

Hundreds of variants clustered in genomic loci and biological pathways affect human height

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N. Maneka G. De Silva, Timothy M. Frayling

ORCID

Novel biological insights emerging from genetic studies of type 2 diabetes and related metabolic traits:

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2009 ) E Zeggini (, John R. B. Perry, Perry ( Jr., Michael N. Weedon

ORCID

, Weedon ( ) Mn, Claudia Langenberg, ) C Langenberg (, Anne U. Jackson, Jackson ( ) Au, Valeriya Lyssenko, ) V Lyssenko (, Thomas Sparso, ) T Sparsø (, Gudmar Thorleifsson, ) G Thorleifsson ( and 104 other authors

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.

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Hana Lango Allen, Stefan Johansson, Sian Ellard, Beverley Shields, Jens K. Hertel, Helge Ræder, Kevin Colclough, Anders Molven, Timothy M. Frayling

ORCID

, Pål R. Njølstad, Andrew T. Hattersley, Michael N. Weedon

ORCID

Polygenic Risk Variants for Type 2 Diabetes Susceptibility Modify Age at Diagnosis in Monogenic HNF1A Diabetes

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Timothy M. Frayling

ORCID

Commentary: A new dawn for genetic epidemiology?

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Rachel M. Freathy

ORCID

, Susan M. Ring, Beverley Shields, Bruna Galobardes, Beatrice Knight, Michael N. Weedon

ORCID

, George Davey Smith, Timothy M. Frayling

ORCID

, Andrew T. Hattersley

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy

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John R. B. Perry, Perry Jr, Mi I. McCarthy, McCarthy Mi, At T. Hattersley, Hattersley At, Wellcome Trust Case Control Consortium, Eleftheria Zeggini, Matthew A. Brown, Linda Bradbury, Weedon Mn, Mn N. Weedon, Tm M. Frayling

ORCID

, Frayling Tm

Interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach.

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Luigi Ferrucci, John R. B. Perry, Amy Matteini, Markus Perola, Toshiko Tanaka, Kaisa Silander, Neil Rice, David Melzer

ORCID

, Anna Murray, Christie Cluett, Linda P. Fried, Demetrius Albanes, Anna-Maria Corsi, Antonio Cherubini, Jack Guralnik and 6 other authors

Common Variation in the β-Carotene 15,15′-Monooxygenase 1 Gene Affects Circulating Levels of Carotenoids: A Genome-wide Association Study

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Rachel M. Freathy

ORCID

, Freathy Rm, Bennett Aj, Amanda J. Bennett, Susan M. Ring, Ring Sm, Beverley Shields, Groves Cj, Christopher J. Groves, Timpson Nj, Nicholas J. Timpson

ORCID

, Weedon Mn, Michael N. Weedon

ORCID

, Eleftheria Zeggini

ORCID

, Lindgren Cm and 21 other authors

Type 2 diabetes risk alleles are associated with reduced size at birth

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2008 Michael N. Weedon

ORCID

, Timothy M. Frayling

ORCID

Reaching new heights: insights into the genetics of human stature

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C. S. Yajnik, C. S. Janipalli, S. Bhaskar, S. R. Kulkarni, R. M. Freathy

ORCID

, S. Prakash, K. R. Mani, M. N. Weedon

ORCID

, S. D. Kale, J. Deshpande, G. V. Krishnaveni, S. R. Veena, C. H. D. Fall, M. I. McCarthy, T. M. Frayling

ORCID

and 2 other authors

FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians

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Timpson Nj, G. {Davey Smith}, Frayling Tm, Nicholas J. Timpson

ORCID

, Pauline M. Emmett, Timothy M. Frayling

ORCID

, Rogers Is, Imogen Rogers, Hattersley At, Andrew T. Hattersley, Mark I. McCarthy, McCarthy Mi, George Davey Smith, George Davey Smith

The fat mass- and obesity-associated locus and dietary intake in children

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