University of Cambridge
55 papers found
The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression.
Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast.
Epigenetic resetting of human pluripotency
The blueprint of primate preimplantation development
Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators.
Tracking the embryonic stem cell transition from ground state pluripotency
EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells
Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass
Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause
Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex
Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis
Glioblastoma Stem Cells Respond to Differentiation Cues but Fail to Undergo Commitment and Terminal Cell-Cycle Arrest
Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human
The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification
Citrullination regulates pluripotency and histone H1 binding to chromatin
Systematic evaluation of spliced alignment programs for RNA-seq data.
A High-Content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-Like Kinase 1
Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor
SMIM1 underlies the Vel blood group and influences red blood cell traits
Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner
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