Najmeh Edraki
0000-0001-8306-2642
36 papers found
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Multifunctional iminochromene-2H-carboxamide derivatives containing different aminomethylene triazole with BACE1 inhibitory, neuroprotective and metal chelating properties targeting Alzheimer's disease
Synthesis and biological evaluation of quinazolinone-based hydrazones with potential use in Alzheimer’s disease
Multi-structure docking analysis of BACE1 crystal structures and non-peptidic ligands
Long Chain Alkyl Esters of Hydroxycinnamic Acids as Promising Anticancer Agents: Selective Induction of Apoptosis in Cancer Cells
Synthesis, docking study and neuroprotective effects of some novel pyrano[3,2- c ]chromene derivatives bearing morpholine/phenylpiperazine moiety
Derivatives of caffeic acid, a natural antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic agents
Molecular dynamics simulation and molecular docking studies of 1,4-Dihydropyridines as P-glycoprotein’s allosteric inhibitors
Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study
Synthesis of novel chromenones linked to 1,2,3-triazole ring system: Investigation of biological activities against Alzheimer’s disease
Discovery of neurotrophic agents based on hydroxycinnamic acid scaffold
2-Imino 2H-chromene and 2-(phenylimino) 2H-chromene 3-aryl carboxamide derivatives as novel cytotoxic agents: synthesis, biological assay, and molecular docking study
Design and synthesis of novel anti-Alzheimer’s agents: Acridine-chromenone and quinoline-chromenone hybrids
Structure-based design, synthesis, molecular docking study and biological evaluation of 1,2,4-triazine derivatives acting as COX/15-LOX inhibitors with anti-oxidant activities
Design, synthesis, and biological evaluation of new series of 2-amido-1,3,4-thiadiazole derivatives as cytotoxic agents
Neuroprotective and Antioxidant Activities of 4-Methylcoumarins: Development of Structure–Activity Relationships
Synthesis and cytotoxic activity of novel poly-substituted imidazo[2,1- $c$ c ][1,2,4]triazin-6-amines
Hydroxycinnamic acid as a novel scaffold for the development of cyclooxygenase-2 inhibitors
Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[h]pyrano[3,2-c]chromene Derivatives: Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[h]pyrano[3,2-c]chromene Derivatives
Inhibitors of Alzheimer’s BACE-1 with 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridine structure
Synthesis, antileishmanial activity and QSAR study of (1,3,4-thiadiazol-2-ylthio) acetamides derived from 5-nitrofuran
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