Vladimír Kryštof

All papers authored by Vladimír Kryštof

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2021 Neetu Dayal, Eva Řezníčková, Delmis E. Hernandez, Miroslav Peřina, Sandra Torregrosa-Allen, Bennett D. Elzey, Jana Škerlová, Haresh Ajani

, Stefan Djukic, Veronika Vojáčková, Martin Lepšík, Pavlína Řezáčová, Vladimír Kryštof

, Radek Jorda

, Herman O. Sintim

3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo

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2018 Tomáš Gucký, Eva Řezníčková, Tereza Radošová Muchová, Radek Jorda, Zuzana Klejová, Veronika Malínková, Karel Berka

, Václav Bazgier, Haresh Ajani

, Martin Lepšík, Vladimír Divoký, Vladimír Kryštof

Discovery of N2-(4-Amino-cyclohexyl)-9-cyclopentyl-N6-(4-morpholin-4-ylmethyl-phenyl)-9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations

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2017 Eva Řezníčková, Lukáš Tenora, Pavlína Pospíšilová, Juraj Galeta, Radek Jorda, Karel Berka

, Pavel Majer, Milan Potáček, Vladimír Kryštof

ALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4 H -pyrrolo[1,2- b ]pyrazoles

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2016 Lorenzo Allegri, Federica Baldan, Catia Mio, Cinzia Puppin, Diego Russo, Vladimir Kryštof

, Giuseppe Damante

Effects of BP-14, a novel cyclin-dependent kinase inhibitor, on anaplastic thyroid cancer cells

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Ladislava Vymětalová, Libor Havlíček, Antonín Šturc, Zuzana Skrášková, Radek Jorda, Tomáš Pospíšil, Miroslav Strnad, Vladimír Kryštof

5-Substituted 3-isopropyl-7-[4-(2-pyridyl)benzyl]amino-1(2)H-pyrazolo[4,3-d]pyrimidines with anti-proliferative activity as potent and selective inhibitors of cyclin-dependent kinases

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Christine B. Baltus, Radek Jorda, Christophe Marot, Karel Berka

, Václav Bazgier, Vladimír Kryštof

, Gildas Prié, Marie-Claude Viaud-Massuard

Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors

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Lukas Jedinak, Vladimir Krystof

, Petr Cankar

The Synthesis and Biological Evaluation of N-Substituted 1H-Benzimidazol-2-yl-1H-pyrazole-3,5-diamines

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2015 Anna Mrozek-Wilczkiewicz, Ewelina Spaczynska, Katarzyna Malarz, Wioleta Cieslik, Marzena Rams-Baron, Vladimír Kryštof

, Robert Musiol

Design, Synthesis and In Vitro Activity of Anticancer Styrylquinolines. The p53 Independent Mechanism of Action

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Avninder S. Bhambra, Mark Edgar, Mark R. J. Elsegood, Yuqi Li, George W. Weaver, Randolph R. J. Arroo, Vanessa Yardley, Hollie Burrell-Saward, Vladimir Krystof

Design, Synthesis and Antitrypanosomal Activities of 2,6-Disubstituted-4,5,7-Trifluorobenzothiophenes

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Veronika Malínková, Jakub Vylíčil, Vladimír Kryštof

Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 – 2014)

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Tomasz M. Wró Bel, Tomasz M. Wróbel, Michał Kiełbus, Agnieszka A. Kaczor

, Vladimír Kryštof

, Zbigniew Karczmarzyk, Waldemar Wysocki, Andrzej Fruziński, Andrzej Fruzin Ski, Sylwia K. Król, L. Sylwia K. Kró, Aneta Grabarska, Andrzej Stepulak, Dariusz Matosiuk

Discovery of nitroaryl urea derivatives with antiproliferative properties

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David Vanda, Radek Jorda, Barbora Lemrová, Tereza Volná, Vladimír Kryštof

, Claire McMaster, Miroslav Soural

Synthesis of Novel N9-Substituted Purine Derivatives from Polymer Supported α-Amino Acids

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Eva Řezníčková, Alexandr Popa, Tomáš Gucký, Marek Zatloukal, Libor Havlíček, Václav Bazgier, Karel Berka

, Radek Jorda, Igor Popa, Abdelmajeed Nasereddin

, Charles L. Jaffe, Vladimír Kryštof

, Miroslav Strnad

2,6,9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro

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Radek Jorda, Eva Schütznerová, Petr Cankař, Veronika Brychtová, Jana Navrátilová, Vladimír Kryštof

Novel arylazopyrazole inhibitors of cyclin-dependent kinases

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2014 Libor Havlíček, Daniela Moravcová, Vladimír Kryštof

, Miroslav Strnad

The Identification of a Novel Highly Condensed Pentacyclic Heteroaromatic Ring System 1,3,5,5b,6,8,10,10b-Octaazacyclopenta[h,i]Aceanthrylene and its Application in the Synthesis of 5,7-Substituted Pyrazolo[4,3-d]Pyrimidines: The Identification of a Novel Highly Condensed Pentacyclic Heteroaromatic Ring System 1,3,5,5b,6,8,10,10b-Octaazacyclopenta[h,i] Aceanthrylene and its

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Radek Jorda, Jana Navrátilová, Zlata Hušková, Eva Schütznerová, Petr Cankař, Miroslav Strnad, Vladimír Kryštof

Arylazopyrazole AAP1742 Inhibits CDKs and Induces Apoptosis in Multiple Myeloma Cells via Mcl-1 Downregulation

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Jitka Holcakova, Petr Muller, Peter Tomasec, Roman Hrstka, Marta Nekulova, Vladimir Krystof

, Miroslav Strnad, Gavin W. G. Wilkinson, Borivoj Vojtesek

Inhibition of Post-Transcriptional RNA Processing by CDK Inhibitors and Its Implication in Anti-Viral Therapy

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Petr Cankař, Lukáš Jedinák, Vladimír Kryštof

, Zdeněk Trávníček

Multicomponent and Regioselective Synthesis of Dihydropyrazolo[1,5-a]pyrimidines from Aromatic Aldehydes, Meldrum’s Acid, and Aminopyrazole CAN508

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Gyte Vilkauskaite, Patricia Schaaf, Algirdas Sackus, Vladimir Krystof

, Wolfgang Holzer

Synthesis of pyridyl substituted pyrazolo 4,3-c pyridines as potential inhibitors of protein kinases

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2013 Aleš Imramovský, Radek Jorda, Karel Pauk, Eva Rezníčková, Jan Dušek, Jiří Hanusek, Vladimír Kryštof

Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines

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All papers authored by Vladimír Kryštof