Qiong Xie - Dissemin

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All papers authored by Qiong Xie

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2024 Zixiang Li, Rufeng Ye, Qian He, Jiashuo Lu, Yanting Sun, Xiujian Sun, Siyuan Tang, Shuyang Hu, Jingrui Chai, Linghui Kong

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, Xiaoning Liu, Jing Chen, Yun Fang, Yingjie Lan, Qiong Xie

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and 5 other authors

Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect

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Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu

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, Qiong Xie

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ORCID

Subtle Structural Changes across the Boundary between A_2AR/A_2BR Dual Antagonism and A_2BR Antagonism: A Novel Class of 2-Aminopyrimidine-Based Derivatives

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2021 Ji-An Chen, Hui Ma, Zehui Liu, Jinlong Tian, Sisi Lu, Wenqing Fang, Shuyin Ze, Weiqiang Lu

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, Qiong Xie

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, Jin Huang, Yonghui Wang

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Discovery of Orally Available Retinoic Acid Receptor-Related Orphan Receptor γ-t/Dihydroorotate Dehydrogenase Dual Inhibitors for the Treatment of Refractory Inflammatory Bowel Disease

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Ruomeng Qiu

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, Juwen Gong, Jinlong Tian, Yafei Huang, Yonghui Wang

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, Qiong Xie

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Discovery of tert-amine-based RORγt agonists

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En-Ming Tian, Ming-Cheng Yu, Mei Feng, Li-Xue Lu, Cheng-Long Liu, Li-An Shen, Yong-Hui Wang, Qiong Xie

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, Di Zhu

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RORγt agonist synergizes with CTLA-4 antibody to inhibit tumor growth through inhibition of Treg cells via TGF-β signaling in cancer

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Nannan Sun, Qiong Xie

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Agonist Lock Touched and Untouched Retinoic Acid Receptor-Related Orphan Receptor-γt (RORγt) Inverse Agonists: Classification Based on the Molecular Mechanisms of Action

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2020 Yuehan Xia, Mingcheng Yu, Yunpeng Zhao, Li Xia, Yafei Huang, Nannan Sun, Meiqi Song, Huimin Guo, Yunyi Zhang, Di Zhu, Qiong Xie

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Discovery of tetrahydroquinolines and benzomorpholines as novel potent RORγt agonists

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Fazhi Yu, Chenyu Zhu, Qiong Xie

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Adenosine A2A Receptor Antagonists for Cancer Immunotherapy

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Nannan Sun, Yafei Huang, Mingcheng Yu, Yunpeng Zhao, Ji-An Chen, Chenyu Zhu, Meiqi Song, Huimin Guo, Qiong Xie

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, Yonghui Wang

Discovery of carboxyl-containing biaryl ureas as potent RORγt inverse agonists

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2019 Yan Zhu, Nannan Sun, Mingcheng Yu, Huimin Guo, Qiong Xie

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Discovery of aryl-substituted indole and indoline derivatives as RORγt agonists

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2018 Xicheng Yang, Jian Shen, Lulu Jiang, Wei Li, Mingcheng Yu, Guanxing Pan, Yurong Yan, Chenghan Zhang, Wanwan Jia, Li Xiao, Haihua Yu, Hao Chen, Yilin Zheng, Linqian Yu, Qiong Xie

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and 2 other authors

Discovery, cocrystallization and biological evaluation of novel piperidine derivatives as high affinity Ls-AChBP ligands possessing α7 nAChR activities

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Yafei Huang, Mingcheng Yu, Nannan Sun, Ting Tang, Fazhi Yu, Xiaoxia Song, Qiong Xie

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, Wei Fu, Liming Shao, Yonghui Wang

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Discovery of carbazole carboxamides as novel RORγt inverse agonists

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2017 Li Xiao

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ORCID

, Qiong Xie

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ORCID

Palladium‐Catalyzed Cascade Saegusa–Heck Reaction: Synthesis of β,β‐Diarylacroleins from Arylpropanals and Aryl Iodides

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Qiong Xie

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, Liming Shao, Hongpeng Sun, Li Xiao, Wei Li

On-Water Silver(I)-Catalyzed Cycloisomerization of Acetylenic Free Amines/Amides towards 7-Azaindole/Indole/Isoquinolone Derivatives

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Qiong Xie

ORCID

, Zhaoxi Zheng, Biyun Shao, Wei Fu, Zheng Xia, Wei Li, Jian Sun, Wei Zheng, Weiwei Zhang, Wei Sheng, Qihong Zhang, Hongzhuan Chen, Hao Wang, Zhuibai Qiu

Pharmacophore-based design and discovery of (−)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis

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Dengqi Xue, Hao Chen, Yulong Xu, Haihua Yu, Linqian Yu, Wei Li, Qiong Xie

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ORCID

Microwave-assisted synthesis of hydroxyl-containing isoquinolines by metal-free radical cyclization of vinyl isocyanides with alcohols

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2013 Ting Liu, Zheng Xia, Wei Zhang, Jian-Rong Xu, Xin-Xing Ge, Juan Li, Yongyao Cui, Zhui-Bai Qiu, Jun Xu, Qiong Xie

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, Hao Wang, Hong-Zhuan Chen

Bis(9)-(−)-nor-meptazinol as a novel dual-binding AChEI potently ameliorates scopolamine-induced cognitive deficits in mice

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2012 Wei Zheng, Juan Li, Zhuibai Qiu, Zheng Xia, Wei Li, Lining Yu, Hailin Chen, Jianxing Chen, Yan Chen, Zhuqin Hu, Wei Zhou, Biyun Shao, Yongyao Cui, Qiong Xie

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, Hongzhuan Chen

Novel bis-(−)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property

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2009 Aviv Paz, Qiong Xie

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, Harry M. Greenblatt, Wei Fu, Yun Tang, Israel Silman, Zhuibai Qiu, Joel L. Sussman

The Crystal Structure of a Complex of Acetylcholinesterase with a Bis-(-)-nor-meptazinol Derivative Reveals Disruption of the Catalytic Triad

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2008 Qiong Xie

ORCID

, Hao Wang, Zheng Xia, Meiyan Lu, Weiwei Zhang, Xinghai Wang, Wei Fu, Yun Tang, Wei Sheng, Wei Li, Wei Zhou, Xu Zhu, Zhuibai Qiu, Hongzhuan Chen

Bis-(−)-nor-meptazinols as Novel Nanomolar Cholinesterase Inhibitors with High Inhibitory Potency on Amyloid-β Aggregation

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