Oxford University Press (OUP), Bioinformatics, 17(30), p. i587-i593
DOI: 10.1093/bioinformatics/btu469
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Motivation: Recently, confocal light sheet microscopy has enabled high-throughput acquisition of whole mouse brain 3D images at the micron scale resolution. This poses the unprecedented challenge of creating accurate digital maps of the whole set of cells in a brain.