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Royal Society of Chemistry, Chemical Science, 2(9), p. 368-379, 2018
DOI: 10.1039/c7sc03450d
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Influences of the heme-lysine crosslink in cytochrome P460 over redox catalysis and nitric oxide sensitivity
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Abstract
A vital role has been identified for the heme-lysine cross-link unique to cytochromes P460: preventing enzyme deactivation during catalysis by the obligate nitrification metabolite nitric oxide.