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Elsevier, Psychiatry Research: Neuroimaging, 2(182), p. 187-190

DOI: 10.1016/j.pscychresns.2010.01.006

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Insular cortex volume in established bipolar affective disorder: a preliminary MRI study

Journal article published in 2010 by Tsutomu Takahashi, Gin S. Malhi, Stephen J. Wood, Murat Yucel ORCID, Mark Walterfang, Ryoichiro Tanino, Michio Suzuki, Christos Pantelis ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

This structural magnetic resonance imaging study investigated insular cortex volume in 26 patients with bipolar I disorder and 24 matched controls. While insular volume did not differ between these groups, exploratory analyses demonstrated that the number of depressive episodes correlated negatively with the anterior insular volume in the patients, suggesting it may have a role in the pathophysiology of bipolar disorder.