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Oxford University Press, Nucleic Acids Research, D1(43), p. D376-D381, 2014

DOI: 10.1093/nar/gku947

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CATH: comprehensive structural and functional annotations for genome sequences

Journal article published in 2014 by Ian Sillitoe, Tony E. Lewis, Alison Cuff, Sayoni Das, Paul Ashford, Natalie L. Dawson, Nicholas Furnham, Roman A. Laskowski ORCID, David Lee, Jonathan G. Lees, Sonja Lehtinen, Romain A. Studer, Janet Thornton, Christine A. Orengo
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235 000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of our functional families (FunFams); the release of our ‘current’ putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages.