Facebook, Twitter, Snapchat, Instagram … It is easy to see that society is in a tide or successive waves of social media. All of this is linked to mobile technology and the expanding role that it plays in people’s lives. This chapter takes a close look at the role of technology in the lives of young people and more specifically in the lives of vulnerable youth. The first section of this chapter examines the ways that social media and mobile technology impact adolescents and young adults, and considers some of the emerging ethical considerations for mental health clinicians and researchers. Next, it examines subsets of youth who are marginalized, including young people with mental illness or autism, and lesbian, gay, bisexual, and transgender (LGBT) youth. Finally, it considers the ethical and neuroethical issues that surround homeless youth and their use of technology.