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American Society for Clinical Investigation, Journal of Clinical Investigation, 11(122), p. 3857-3859, 2012

DOI: 10.1172/jci65929

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Amazing IL-9: revealing a new function for an “old” cytokine

Journal article published in 2012 by Edgar Schmitt, Tobias Bopp
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The incidence of melanoma — the most aggressive form of skin cancer — is dramatically increasing, while the development of innovative therapeutic strategies continues to be challenging, especially due to a lack of knowledge about the molecular mechanisms underlying melanoma progression as well as antitumor immunity. In this issue of the JCI, Yong Lu and colleagues report a central role for Th9 cells in antitumor immunity.